


Cabagin Kowa α Plus
For stomachs weakened by aging. A comprehensive gastrointestinal medicine containing MMSC, a gastric mucosa repair ingredient derived from cabbage.
For these people and occasions
Product overview
Cabagin Kowa α Plus is a trusted comprehensive gastrointestinal medicine developed and improved by Kowa Co., Ltd. for over 60 years since 1960. Centered on the gastric mucosa repair ingredient MMSC (methylmethionine sulfonium chloride) discovered from cabbage juice, it combines stomach-strengthening herbs (Houpo, Soyou, Swertia), antacids, and digestive enzymes to support repair of damaged gastric mucosa and recovery of weakened stomach function from multiple angles.
The tablet adopts a unique "double layer (double-layer structure)." The outer layer antacid first neutralizes stomach acid to relieve pain, then the inner core tablet slowly dissolves, allowing each active ingredient to work more effectively. Suitable for those feeling age-related stomach decline or who often overeat or overdrink for gastrointestinal care.
Product features
Gastric mucosa repair action + antacid action
MMSC, sodium bicarbonate, magnesium hydroxideMMSC (methylmethionine sulfonium chloride), discovered from cabbage juice, cares for damaged gastric mucosa. Three types of antacids neutralize excess stomach acid and protect the stomach from acid irritation.
Stomach-strengthening + digestive action
Houpo, Soyou, Swertia, Lipase AP12Contains stomach-strengthening herbs Houpo, Soyou, and Swertia to revitalize weakened stomach function. Lipase AP12 promotes fat digestion and supports relief from indigestion caused by fatty meals.
Double layer (double-layer structure)
Outer layer: antacid / Inner layer: active ingredientsThe double-layer structure of the outer layer and core tablet allows each active ingredient to work stepwise and effectively. First, the outer layer antacid neutralizes stomach acid, then the inner layer slowly dissolves to activate stomach-strengthening and repair ingredients.
Can be taken from 8 years old
Take after each meal / Dosage by ageAdults (15 years and older) take 2 tablets per dose, 8 years to under 15 years take 1 tablet per dose, 3 times a day after meals. Designed for a wide age range. Do not give to children under 8 years old.
Active ingredients
| Ingredient name | Content (per 6 tablets) | Classification |
|---|---|---|
| Methylmethionine sulfonium chloride (MMSC) | 150.0mg | Gastric mucosa repair agent |
| Sodium bicarbonate | 600.0mg | Antacid |
| Magnesium hydroxide | 210.0mg | Antacid |
| Precipitated calcium carbonate | 1,340.0 mg | Antacid |
| Rohto extract triple powder (30.0 mg as Rohto extract) | 90.0mg | Antacid |
| Dried Soyou extract (180.0 mg as Soyou) | 20.0mg | Stomach-strengthening medicinal herbs |
| Dried Houpo extract (180.0 mg as Houpo) | 15.0mg | Stomach-strengthening medicinal herbs |
| Swertia powder | 30.0mg | Stomach-strengthening medicinal herbs |
| Biodiastase 2000 | 24.0mg | Digestive enzymes |
| Lipase AP12 | 15.0mg | Digestive enzymes |
Efficacy and effects
Dosage and administration
| Age | Dose per time | Number of doses per day | Timing of administration |
|---|---|---|---|
| Adults (15 years and older) | 2 tablets | 3 times | After every meal |
| 8 years old to under 15 years old | 1 tablet | 3 times | After every meal |
| Under 8 years old | Do not take | ||
Comparison with other products
| Comparison items | [Cabagin Kowa α Plus] | Ohta's Isan |
Taisho Kampo Gastrointestinal Medicine |
|---|---|---|---|
| Drug classification | Class 2 OTC Drug | Class 2 OTC Drug | Class 2 OTC Drug |
| Dosage form | Tablet (double-layer structure) | Powder (packets) | Fine granules (packets) |
| Manufacturer | Kowa Co., Ltd. | Ohta's Isan Co., Ltd. | Taisho Pharmaceutical Co., Ltd. |
| Main characteristic ingredients | MMSC (gastric mucosa repair) + 3 types of stomach-strengthening medicinal herbs + digestive enzymes | 7 types of stomach-strengthening medicinal herbs + 3 types of antacids + digestive enzymes | Anchusan + Shaoyao Gancao extract (2 types of herbal medicine formula) |
| Gastric mucosa repair ingredient | Contains MMSC | No active ingredients | No active ingredients |
| Antacid | Contains 4 types | Contains 3 types | Only Borei (oyster) |
| Digestive enzymes | Biodiastase and Lipase AP12 | Biodiastase | No active ingredients |
| Main effects (overview) | Indigestion, stomach pain, overeating, overdrinking, nausea, digestion promotion, etc. (17 symptoms) | Indigestion, stomach pain, overeating, overdrinking, heartburn, etc. (17 symptoms) | Indigestion, stomach discomfort, stomach pain, loss of appetite, abdominal pain, etc. (12 symptoms) |
| Timing of administration | After every meal | After or between meals | Before or between meals |
| Use in children | Suitable for 8 years and older | Suitable for 8 years and older | Suitable for 5 years and older |
| Pregnancy and breastfeeding | Do not take or avoid breastfeeding while taking during breastfeeding | Safe for use during pregnancy and breastfeeding (with caution) | Consult a doctor or pharmacist recommended |
| Distinctive approach | "Repair" + "Energy Recovery" two-step care (two-layer structure) | Powder with a refreshing taste from aromatic herbal medicines | Gastrointestinal care for constitutional improvement with two types of herbal formulas |
❓ Frequently Asked Questions
QWho is this recommended for?
AThis is recommended for those who feel indigestion after meals, have stomach pain unrelated to meals, or feel discomfort and cannot eat even after eating a little. It not only improves unpleasant symptoms such as indigestion, stomach pain, and nausea but also cares for damaged stomach mucosa and helps restore weakened stomach function to normal.
QIs it okay to take it every day?
AIf effective, you may continue taking it. However, if symptoms do not improve after about two weeks, stop taking it and consult a doctor, pharmacist, or registered seller.
QWhen should I take it?
ATake three times a day after each meal with water or warm water.
QCan I take this medicine while breastfeeding?
AIf you are breastfeeding, do not take this medicine or avoid breastfeeding while taking it. Rohto extract may pass into breast milk and cause a rapid heartbeat in the infant.
QCan children take this medicine?
ADo not give to children under 8 years old. For those 8 years and older, administer under the guidance and supervision of a guardian.
🌱 Brand Story
The effectiveness of MMSC (methylmethionine sulfonium chloride) contained in cabbage was discovered, starting the development of Cabagin.
Kowa Co., Ltd. launched the first "Cabagin Kowa Tablet." It was born as a gastrointestinal medicine to improve indigestion and discomfort caused by overeating and overdrinking. The name "Cabagin" comes from "cabbage in."
Added Lipase AP12 to aid fat digestion, responding to the Westernization of the Japanese diet.
Contains the stomachic herbal medicine Soyou, which improves weakened stomach function, enabling more comprehensive care.
Added the stomachic herbal medicine Kouboku, evolving into the current Cabagin Kowa α Plus. It has continued to evolve for over 65 years to meet the needs of the times.
- Do not use gastrointestinal analgesic antispasmodics while taking this medicine.
- If you are breastfeeding, do not take this medicine or avoid breastfeeding while taking it (Rohto extract may pass into breast milk and cause a rapid heartbeat in the infant).
- If symptoms do not improve after about two weeks of use, stop taking the medicine and consult a doctor, pharmacist, or registered seller.
- This medicine is to be taken after meals. Please follow the dosage and administration instructions.
- Consult a doctor, pharmacist, or registered seller if you are receiving medical treatment, have had allergic reactions to medicines, or are pregnant.
- If symptoms such as rash, redness, itching, dry mouth, or constipation appear after taking this medicine, stop taking it and consult a doctor, pharmacist, or registered seller.
- Store in a cool place, avoiding direct sunlight, high temperature, and humidity.
- Keep out of reach of children.
- Do not transfer to another container (may cause misuse or quality changes).






















































































