Works quickly and effectively,
No drowsiness-causing ingredients included
Point1 Effective quickly and well for menstrual cramps and headaches
Adopts a double formulation of two analgesic ingredients, "ibuprofen" and "acetaminophen." It quickly blocks pain from both the central and peripheral nervous systems.
Point2 No drowsiness-causing ingredients included
Even if the pain subsides, you want to avoid feeling "sleepy" or "sluggish." Therefore, it does not contain ingredients that cause drowsiness.
Point3 Small and easy to swallow
We focused on selecting active ingredients and the manufacturing process, successfully creating small, easy-to-swallow tablets.
Point4 Gentle on the stomach
Contains the stomach mucosa protective ingredient "dry aluminum hydroxide gel." It also addresses concerns for those worried about stomach burden.
Why double formulation?
Menstrual cramps and headaches each have their own "source of pain," and pain occurs when signals are "transmitted" to the brain from these sources. That is why it is important to target these two points: the "source of pain" and the "transmission."
● Features
Bufferin has products with different active ingredients. The antipyretic analgesic ingredients of this product are ibuprofen and acetaminophen. When consulting a doctor, dentist, pharmacist, or registered seller, please inform them of ibuprofen and acetaminophen.
■ Works quickly and effectively
・Contains ibuprofen and acetaminophen
・Quickly dissolving "Quick Melt Tablets"＊
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■ Does not contain ingredients that cause drowsiness
■ Small and easy to swallow
■ Gentle on the stomach
＊Manufacturing patent No. 4065902 Granulated particles, tablets, and manufacturing method of granulated particles
【Designated Class 2 OTC Drug】
● Efficacy/Effects
Relief of menstrual pain (period pain), headache, lower back pain, stiff shoulders pain, muscle pain, joint pain, bruising pain, fracture pain, sprain pain, toothache, pain after tooth extraction, neuralgia, ear pain, trauma pain, sore throat pain. Antipyretic for chills and fever.
＜Precautions related to Efficacy/Effects＞
● Dosage and Administration
Avoid taking on an empty stomach as much as possible, and keep an interval of 4 hours or more between doses. Take the following amount with water or lukewarm water.
［Age: Dose per time: Number of doses per day］
Adults (15 years and older): 2 tablets: up to 3 times
Under 15 years: Do not take
＜Precautions related to Dosage and Administration＞
(1) Strictly follow the dosage and administration.
(2) How to take out the tablets: Press strongly on the convex part of the PTP sheet containing the tablets with your fingertip to break the aluminum foil on the back, take out the tablet, and then take it (swallowing it accidentally as is may cause unexpected accidents such as piercing the esophageal mucosa).
● Ingredients/Quantity
Per 2 tablets
Ibuprofen 130 mg
Acetaminophen 130 mg
Anhydrous caffeine 80 mg
Dried aluminum hydroxide gel 70 mg
〔Additives〕
Hydroxypropyl cellulose, D-mannitol, lactic acid, magnesium stearate, polyvinyl alcohol (partially saponified), talc, titanium oxide, glycerin fatty acid ester, sodium lauryl sulfate
＜Precautions related to Ingredients/Quantity＞
● Dosage Form
Film-coated tablets (oral - tablets)
● Precautions for Use
■Do not do (Contraindications)
(If not followed, current symptoms may worsen or side effects/accidents may occur more easily)
1. Do not take if you fall under the following:
(1) Have had allergic symptoms caused by this drug or its ingredients.
(2) Have had asthma caused by this drug or other antipyretic analgesics or cold medicines.
(3) Children under 15 years old.
(4) Pregnant women within 12 weeks before the expected delivery date.
2. Do not take any of the following medicines while taking this drug:
Other antipyretic analgesics, cold medicines, sedatives
3. Do not drink alcohol before or after taking this medicine.
4. Do not take continuously for a long time.
■Consult
1. Consult a doctor, dentist, pharmacist, or registered seller before taking if you fall under the following:
(1) Receiving treatment from a doctor or dentist.
(2) Pregnant or suspected to be pregnant.
(3) Breastfeeding.
(4) Elderly.
(5) Have had allergic symptoms caused by drugs, etc.
(6) Diagnosed with heart disease, kidney disease, liver disease, systemic lupus erythematosus, mixed connective tissue disease.
(7) Have had stomach/duodenal ulcer, ulcerative colitis, Crohn's disease.
2. If the following symptoms appear after taking, they may be side effects, so stop taking immediately and consult a doctor, dentist, pharmacist, or registered seller with this document.
［Affected area: Symptoms］
Skin: Rash, redness, itching, bruising
Digestive system: Nausea, vomiting, loss of appetite, stomach discomfort, stomach pain, stomatitis, heartburn, indigestion, gastrointestinal bleeding, abdominal pain, diarrhea, bloody stool
Nervous system: Dizziness
Circulatory system: Palpitations
Respiratory system: Shortness of breath
Others: Blurred vision, tinnitus, swelling, nosebleed, bleeding gums, bleeding that is hard to stop, bleeding, back pain, excessive body temperature drop, fatigue
Rarely, the following serious symptoms may occur. In such cases, seek medical attention immediately.
［Name of Symptom: Symptom］
Shock (Anaphylaxis): Immediately after taking, itching of the skin, hives, hoarseness, sneezing, throat itching, difficulty breathing, palpitations, clouding of consciousness, etc. appear.
Stevens-Johnson syndrome: High fever, eye redness, eye discharge, lip erosion, sore throat, widespread rash/redness on the skin, small bumps (small pustules) on the reddened skin, general fatigue, loss of appetite, etc. persist or worsen rapidly.
Toxic epidermal necrolysis: High fever, eye redness, eye discharge, lip erosion, sore throat, widespread rash/redness on the skin, small bumps (small pustules) on the reddened skin, general fatigue, loss of appetite, etc. persist or worsen rapidly.
Acute generalized exanthematous pustulosis: High fever, eye redness, eye discharge, lip erosion, sore throat, widespread rash/redness on the skin, small bumps (small pustules) on the reddened skin, general fatigue, loss of appetite, etc. persist or worsen rapidly.
Drug hypersensitivity syndrome: Widespread redness of the skin, systemic rash, fever, fatigue, swelling of lymph nodes (neck, armpits, groin, etc.) appear.
Liver dysfunction: Fever, itching, rash, jaundice (yellowing of skin and whites of eyes), brown urine, general fatigue, loss of appetite, etc. appear.
Kidney disorder: Fever, rash, decreased urine output, generalized swelling, general fatigue, joint pain, diarrhea, etc. appear.
Aseptic meningitis: Severe headache with neck stiffness, fever, nausea, vomiting, etc. appear (these symptoms are frequently reported especially in people receiving treatment for systemic lupus erythematosus or mixed connective tissue disease).
Interstitial pneumonia: Shortness of breath or difficulty breathing when climbing stairs or exerting slightly, dry cough, fever, etc. appear suddenly or persist.
Asthma: Wheezing or whistling sounds when breathing, difficulty breathing, etc. appear.
Aplastic anemia: Bruising, nosebleeds, bleeding gums, fever, pale skin and mucous membranes, fatigue, palpitations, shortness of breath, dizziness, hematuria, etc. appear.
Agranulocytosis: Sudden high fever, chills, sore throat, etc. appear.
3. The following symptoms may appear after taking; if these symptoms persist or worsen, stop taking and consult a doctor, pharmacist, or registered seller with this document.
Constipation
4. If symptoms do not improve after 5 to 6 doses, stop taking and consult a doctor, dentist, pharmacist, or registered seller with this document.
●Precautions for Storage and Handling
(1) Store in a cool, dry place away from direct sunlight.
(2) Keep out of reach of children.
(3) Do not transfer to other containers (may cause misuse or quality changes).
(4) Do not use products past the expiration date.
(5) To prevent deterioration, do not damage the aluminum foil on the back of tablets that you do not take.
