Hada Labo Shirojyun Premium
Medicated penetrating whitening Cream
Deeply approaches melanocytes, the source of spots. The serum-grade double active ingredients provide clarity and moisture in this medicated whitening Cream.
"Hada Labo Shirojyun Premium Quasi-drug Penetrating Whitening Cream" is a medicated whitening Cream that focuses on moisture and brightness, with a rich feel that is non-sticky and penetrates smoothly. It penetrates deeply into the stratum corneum damaged by UV rays, approaches melanocytes that cause spots, and leads to moist, bright skin. It has the same weak acidity as healthy bare skin. The formula is designed with gentleness to the skin in mind.
Two active ingredients for whitening + anti-inflammatory
Whitening active ingredient white tranexamic acid★ approaches melanocytes. Additionally, anti-inflammatory active ingredient dipotassium glycyrrhizate addresses inflammation-related dullness.
Tranexamic acid + dipotassium glycyrrhizateMoisture penetration with two types of hyaluronic acid
Contains nano hyaluronic acid (hydrolyzed hyaluronic acid) and sodium hyaluronate-2. Fine particles penetrate deeply into the stratum corneum, maintaining a plump moisturizing feel for a long time.
Nano HA + Sodium hyaluronate-2Rich yet light feel with shea butter + squalane
Contains moisturizing oils shea butter and sugar squalane. Despite the rich Cream texture, it smoothly blends into the skin with a non-sticky finish.
Contains shea butter and sugar squalaneGentle design of "Perfect Simple®"
A 5-free formula: fragrance-free, colorant-free, mineral oil-free, alcohol (ethanol)-free, and paraben-free. A design philosophy unique to Rohto Hada Labo that thoroughly considers sensitive skin.
5-free formula




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| Ingredient name | Category | General function |
|---|---|---|
| Tranexamic acid (White tranexamic acid★) | Active ingredient (whitening) | Approaches melanocytes to suppress melanin production, preventing spots and freckles |
| Dipotassium glycyrrhizate | Active ingredient (anti-inflammatory) | Suppresses inflammation caused by UV damage and prevents dullness and rough skin |
| Hydrolyzed hyaluronic acid (nano hyaluronic acid)☆ | Other ingredients | Fine particles penetrate deeply into the stratum corneum, providing high moisturizing effect |
| Sodium hyaluronate-2☆ | Other ingredients | Retains moisture on the skin surface and maintains smooth skin |
| Magnesium ascorbyl phosphate (Vitamin C derivative)* | Other ingredients | Skin conditioning, moisturizing effect, and antioxidant support |
| Vitamin E | Other ingredients | Skin conditioning, antioxidant support, and moisturizing support |
| Shea butter | Other ingredients | Emollient (moisturizing oil that softens the stratum corneum and prevents water evaporation) |
| Sugar squalane | Other ingredients | Plant-derived squalane. An emollient ingredient that absorbs well into the skin and is non-greasy |
| Meadowfoam seed Oil | Other ingredients | Plant-based Oil that enhances skin flexibility and smoothness |
| DPG and diglycerin | Other ingredients | Polyhydric alcohols blended as moisturizers and solvents |
| Dimethicone | Other ingredients | Silicone-based emollient that smooths the skin surface |
| Carboxyvinyl polymer and xanthan gum-based | Other ingredients | Forms the texture of the Cream (thickening and gelling) |
| Phenoxyethanol | Other ingredients | Preserves product quality as a preservative |
★ Product name: "Rohto HP Medicated Whitening Cream a" ☆ Two types of hyaluronic acid * Vitamin C derivative (Vitamin C phosphate Mg)
* "General functions" describe the general functions of the ingredients and do not indicate the efficacy of this product.
* "Whitening" refers to suppressing melanin production to prevent spots and freckles. This is displayed within the scope of efficacy based on Japan's Pharmaceutical and Medical Device Act (Quasi-drug).
| Steps | Method & Tips |
|---|---|
| ① After cleansing, condition with lotion | Use after cleansing and conditioning your skin with lotion or similar. |
| ② Take an appropriate amount on the palm | Take an appropriate amount (about the size of a pearl) on the palm. |
| ③ Gently spread over the entire face | Gently spread over the entire face and press in smoothly to blend. |
| ④ About crystals on the cap | If crystals of the whitening ingredient stick to the cap, please wipe them off with a clean gauze or similar before use. |
| ⑤ Use in the morning and at night | Can be used as the final step of morning and night skincare (instead of lotion) or layered after serum. |
Hada Labo is a skincare brand launched by Rohto Pharmaceutical in 2004. Under the philosophy of "Perfect Simple®", which means "no unnecessary ingredients, only pursuing what is necessary," it consistently maintains a fragrance-free, colorant-free, alcohol (ethanol)-free, mineral oil-free, and paraben-free formulation.
The Hakuju Premium series was developed with the concept of "preventing spots and rough skin while providing moisture and aiming for naturally clear skin." In addition to the whitening active ingredient tranexamic acid, it includes the anti-inflammatory active ingredient dipotassium glycyrrhizate to address inflammation and dullness caused by UV damage. It is not just a "moisturizing cream" but condenses serum-level functions into one cream.
Rohto Pharmaceutical is a leading comprehensive healthcare manufacturer based in Osaka, Japan, conducting research and development in a wide range of fields including pharmaceuticals, skincare, and eye care. Since 2005, Hada Labo has gained wide support not only in Japan but throughout Asia, including Southeast Asia.
- Use with care, paying close attention to any abnormalities on your skin. If redness, swelling, itching, irritation, discoloration (such as white spots), or darkening occurs during or after use when exposed to sunlight, stop using and consult a dermatologist. Continuing use may worsen symptoms.
- Do not use on wounds, swelling, eczema, or other abnormal areas.
- Be careful not to get it in your eyes. If it does, rinse immediately with water or lukewarm water. If abnormalities persist, consult an ophthalmologist.
- Discontinue use if it does not suit your skin.
- Avoid storing in direct sunlight, high temperatures, or low temperatures.
- Always tightly close the cap after use and store it cleanly.
- Keep out of reach of infants and young children.
- Crystals of the whitening ingredient may stick to the cap, but there is no problem with the quality. Please wipe them off with a clean gauze or similar before use.











































































