Hada Labo Gokujyun®
Medicated Firming Cream
Niacinamide offers a dual approach to wrinkle improvement + spot prevention.
With a rich cream of 3 types of hyaluronic acid × Shea Butter,
For firm, plump skin.
Product Overview
Hada Labo Gokujyun® Medicated Firming Cream is a cream from Rohto Pharmaceutical's "Hada Labo®" Gokujyun Aging Care Series. Developed as a Quasi-drug cream for aging skin that achieves "wrinkle improvement + spot prevention + high moisture" all in one. The product name is Rohto H Medicated Wrinkle Cream a.
The active ingredient Niacinamide improves wrinkles by promoting epidermal turnover and collagen production in the dermis, while also preventing spots and freckles by inhibiting melanin transfer to melanocytes. Its greatest feature is the ability to simultaneously address wrinkle improvement and spot prevention with a single active ingredient.
Contains moisturizing ingredients including 3 types of hyaluronic acid (Hyaluronic Acid Na-2, Hydrolyzed Hyaluronic Acid, Acetylated Hyaluronic Acid Sodium) and Acetyl Glucosamine. It also includes Shea Butter and Hardened Oil to replenish oils needed for aging skin, plant-based skin conditioning ingredient Oubaku Extract, and antioxidant d-δ-Tocopherol (natural Vitamin E), delivering rich moisture and firmness to dry adult skin. Formulated to be weakly acidic, fragrance-free, colorant-free, mineral oil-free, alcohol-free, and paraben-free.
Four Features
Improve wrinkles with Niacinamide
With age, collagen in the dermis decreases, making wrinkles more noticeable. The active ingredient Niacinamide promotes epidermal turnover and further stimulates collagen production in the dermis, delivering wrinkle improvement effects approved as a Quasi-drug, not just a functional food.
Inhibits melanin transfer to prevent spots
Niacinamide inhibits the process of melanin transfer from melanocytes to surrounding skin cells, suppressing melanin production to prevent spots and freckles. It is a rare active ingredient that offers a dual approach to wrinkle improvement and whitening care in one.
High-density hydration with 3 types of hyaluronic acid + Acetyl Glucosamine
Three types of hyaluronic acid that widely moisturize the skin surface: Hyaluronic Acid Na-2 (holds 6L of water per 1g), Acetylated Hyaluronic Acid Sodium (Super Hyaluronic Acid) with twice the usual moisture retention, and Hydrolyzed Hyaluronic Acid (Nano Hyaluronic Acid) that penetrates deep into the stratum corneum, plus Acetyl Glucosamine that promotes hyaluronic acid production in the body, provide multifaceted hydration.
Shea Butter & Oubaku Extract replenish oils and prevent roughness in aging skin
For aging skin prone to dryness due to decreased sebum secretion with age, plant-derived oil Shea Butter replenishes oils and prevents moisture evaporation. Plant-based skin conditioning ingredient Oubaku Extract (Phellodendron Extract) prevents rough skin and conditions the skin. d-δ-Tocopherol (natural Vitamin E) protects the skin from oxidative stress.
Niacinamide's Dual Approach
Wrinkle Improvement Mechanism
As collagen in the dermis decreases with age, the skin's foundation weakens, causing wrinkles. Niacinamide promotes epidermal turnover and simultaneously stimulates collagen production in the dermis, restoring skin elasticity and firmness, delivering wrinkle improvement recognized as a Quasi-drug.
Spot Prevention Mechanism
Melanin pigment produced in melanocytes due to UV stimulation and other factors is transferred to surrounding cells (keratinocytes), accumulating as spots. Niacinamide inhibits this melanin transfer process, suppressing melanin production to prevent spots and freckles.
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Ingredients
| Ingredient Name | Category | Main Functions |
|---|---|---|
| Active Niacinamide | Active Ingredients (Wrinkle Improvement & Whitening) | Double effect of wrinkle improvement by promoting collagen production and prevention of spots and freckles by inhibiting melanin transfer with one ingredient. |
| Moisturizing Sodium Hyaluronate-2 | Moisturizing ingredients | Has high water retention capacity, holding 6L of water per gram, providing and maintaining moisture on the skin surface. |
| Moisturizing Hydrolyzed Hyaluronic Acid (Nano Hyaluronic Acid) | Moisturizing ingredients | Ultrafine particles about 1/100th the size penetrate deep into the stratum corneum to deliver moisture from within. |
| Moisturizing Acetylated Sodium Hyaluronate (Super Hyaluronic Acid) | Moisturizing ingredients | Has twice the water retention capacity of regular hyaluronic acid. Holds moisture tightly while blending with the skin's lipid film. |
| Moisturizing Acetyl Glucosamine | Moisturizing ingredients (exclusive to aging care) | Promotes hyaluronic acid production in the body. Included only in the Gokujyun Aging Care series. |
| Skin conditioning Phellodendron Extract | Plant-based skin conditioning ingredients | Plant-derived skin conditioning ingredients that prevent rough skin and improve skin condition. |
| Oil Shea Butter | Emollient ingredients (plant-derived) | Supplies oil to dry aging skin, prevents moisture evaporation, and keeps skin soft and hydrated. |
| Antioxidant d-δ-Tocopherol | Natural Vitamin E | Antioxidant ingredients that remove free radicals, protect the skin from oxidative stress, and prevent skin aging. |
| Hardened Oil & Tri(caprylic/capric acid) Glyceryl | Emollient & Oil base | Forms a smooth cream texture and contributes to oil replenishment and prevention of moisture evaporation. |
| α-Olefin Oligomer | Emollient ingredients | Synthetic oils that blend well with the skin, providing a light feel and moisture. |
| Concentrated Glycerin & BG | Moisturizers | Basic moisturizing ingredients that directly hydrate the skin and enhance formulation stability and moisturizing power. |
| Pullulan | Film-forming & Skin conditioning ingredients | Polysaccharide components that form a thin film on the skin surface to lock in moisture. |
| Behenyl Alcohol & Stearyl Alcohol | Emulsifier & Texture adjuster | High-grade alcohol components that adjust cream stability and spreadability. |
| Carbomer & TEA | Thickening agent & pH adjuster | Forms a dense cream texture while maintaining weak acidity. |
| Phenoxyethanol & Edetate | Preservatives & Chelating agents | Maintains product quality and safety, preventing microbial contamination and deterioration caused by metal ions. |
* Active ingredient: Niacinamide / Other ingredients: Sodium Hyaluronate-2, Hydrolyzed Hyaluronic Acid, Acetylated Sodium Hyaluronate (*3 types of Hyaluronic Acid), Acetyl Glucosamine, Phellodendron Extract, Shea Butter, d-δ-Tocopherol, Concentrated Glycerin, BG, Hardened Oil, Tri(caprylic/capric acid) Glyceryl, α-Olefin Oligomer, 1,2-Pentanediol, Polyglyceryl-3 Triisostearate, Isostearic Acid POE (20) Sorbitan, Polyoxyethylene Behenyl Ether, Dimethicone, Pullulan, Carbomer, TEA, Edetate, Anhydrous Citric Acid, Behenyl Alcohol, Stearyl Alcohol, Phenoxyethanol
* Ingredient list is based on Rohto Online Shop and Matsukiyo information. Please check the latest information in the attached document.
Efficacy & Effects
This product is recognized as a Quasi-drug with the following efficacies and effects.
* This product is not a medicine and is not intended for diagnosis, treatment, or prevention of diseases.
* The efficacy of "improving wrinkles" is approved as a Quasi-drug. However, it does not completely erase deep wrinkles (furrows), and effects vary by individual.
* "Whitening" means suppressing melanin production to prevent spots and freckles; it does not remove already formed spots (treatment effect).
* Aging care means moisturizing care according to your age.
How to use / Directions
| Items | Contents |
|---|---|
| Usage timing | Use as the final step of skincare after preparing your skin with lotion (or milk lotion). Can be used both morning and night. More effective when focused on at night. |
| Recommended amount | Take an appropriate amount (about the size of a small bean to a pearl) on your palm and gently blend it all over your face. You may increase the amount on dry areas. |
| Basic usage | ① After washing your face, replenish plenty of moisture with lotion (Quasi-drug Harilotion) ② Apply milk lotion (Quasi-drug Harimilk) as needed ③ Spread an appropriate amount of Quasi-drug Hari Cream on your palm and gently apply it all over your face ④ Gently blend with fingertips on areas of concern such as around the eyes and mouth |
| Using the series | Morning: Quasi-drug Harilotion → Quasi-drug Harimilk or Hari Cream Night (Intensive care): Quasi-drug Harilotion (apply 2-3 times) → Quasi-drug Harimilk → Quasi-drug Hari Cream Time-saving: Hariperfect Gel (All-in-One) can be used alone |
| Content & Price | 50g (Open price) Reference Price: ¥1,826 (tax included / Rohto Online Shop) *No refill currently available |
| JAN Code / Product Name | JAN: 4987241171316 Product Name: Rohto H Medicated Wrinkle Cream a Manufacturer and Distributor: Rohto Pharmaceutical Co., Ltd. (1-7-5 Shiba, Minato-ku, Tokyo) |
Frequently Asked Questions
*Source: Rohto Pharmaceutical official FAQ (https://faq.rohto.com/faq_detail.html?id=1468&category=84&page=1)
*Source: Based on recommended usage from Rohto Pharmaceutical's official Gokujyun Aging Care page
Brand Story
Birth of "Gokujyun Aging Care" for mature skin
Hada Labo®, created by Rohto Pharmaceutical in 2004 with the philosophy of "Perfectly Simple," is a national brand that has grown to be Japan's No.1 in domestic sales volume for 14 consecutive years in the skincare cosmetics category (Intage SRI/SRI+ data), delivering only the necessary ingredients at the highest purity.
The Gokujyun Aging Care series was developed to directly address the two major skin concerns that become apparent with age: wrinkles and spots. The active ingredient Niacinamide (a type of Vitamin B3) is recognized as effective for both wrinkle improvement and spot treatment as a Quasi-drug. Combined with Rohto Pharmaceutical's hyaluronic acid research, it achieves "wrinkle improvement + spot treatment + high moisture retention" in one product.
The aging care series known as "Red Gokujyun" continues to support mature skin under the Hada Labo® sustainability policy, promoting refill options and the use of environmentally friendly materials.
Usage Precautions
⚠ Usage Precautions
- Do not use on wounds, swelling, eczema, or other abnormal areas.
- Use with care, paying close attention to any skin abnormalities. If redness, swelling, itching, irritation, discoloration (such as white spots), or darkening occurs during or after use when exposed to sunlight, stop use and consult a dermatologist. Continuing use may worsen symptoms.
- Avoid contact with eyes; if it gets into eyes, rinse immediately with water or lukewarm water. Consult an ophthalmologist if abnormalities persist.
- Discontinue use if it does not suit your skin.
- For external use only. Do not ingest.
Storage Precautions
📦 Storage and Handling Precautions
- After use, close the cap tightly and store.
- Avoid direct sunlight, high temperatures, and low temperatures; store at room temperature.
- Keep out of reach of infants and young children.
- Do not transfer to other containers (may cause misuse or quality changes).
- This product is not classified as an aviation hazardous material under the Aviation Law (follow each airline's regulations for carry-on).
