Hada Labo Premium®
Medicated penetrating whitening lotion
Moist type
Directly approaches melanocytes, the source of spots.
Serum-grade moist whitening lotion with double active ingredients × two types of hyaluronic acid.
Product overview
Hada Labo Premium® Medicated Penetrating Whitening Lotion (moist type) is the top whitening line of Rohto Pharmaceutical's "Hada Labo®" brand. Designed for those who want to pursue both moisture and whiteness simultaneously with a rich, serum-like formula.
Compared to the regular Hada Labo series, the biggest feature is the double formulation of active ingredients. Whitening active ingredient White Tranexamic Acid® (Tranexamic Acid) suppresses the production of inflammatory substances in the early stage of spot formation, and the additional anti-inflammatory active ingredient Glycyrrhizic Acid 2K supports the prevention of rough skin and acne.
Contains two moisturizing ingredients: Nano Hyaluronic Acid (Hydrolyzed Hyaluronic Acid) and Hyaluronic Acid Na-2. Combined with skin conditioning and moisturizing ingredients Vitamin C derivative and Vitamin E, it penetrates deep into the stratum corneum damaged by UV rays and directly approaches melanocytes, the source of spots. Formulated to be weakly acidic, fragrance-free, colorant-free, mineral oil-free, alcohol (ethanol)-free, and paraben-free.
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Four features
Double active ingredients to block spots and rough skin
Whitening active ingredient White Tranexamic Acid® suppresses the production of inflammatory substances that cause spots from the initial stage. Anti-inflammatory active ingredient Glycyrrhizic Acid 2K further prevents rough skin and acne, creating a clear skin base with double active ingredients. This is the biggest differentiating point from the regular Hada Labo version.
Direct approach to melanocytes
Penetrates deep into the stratum corneum of skin damaged by UV rays and directly acts on pigment cells (melanocytes) that cause spots. As the name "penetrating whitening" suggests, it features a deep approach beyond surface care.
Moist rich formula with two types of hyaluronic acid
Nano Hyaluronic Acid, which is micronized to about 1/100 the particle size of regular hyaluronic acid, penetrates deep into the stratum corneum, and Hyaluronic Acid Na-2, which holds 6L of water per gram, broadly maintains moisture on the skin surface. The moist, rich texture delivers satisfying hydration even for those concerned about dryness.
Skin conditioning and moisturizing ingredients that refine skin texture
Vitamin C Phosphate Mg (Vitamin C derivative) conditions the skin from inside the stratum corneum, and Vitamin E conditions it from the outside, preventing dryness caused by UV damage. It replenishes moisture and firmness, leading to smooth skin with refined texture.
Difference between Hada Labo and Hada Labo Premium
🔵 Hada Labo Medicated Whitening Lotion
- Active ingredient: Tranexamic Acid (single)
- Contains Allantoin (prevents rough skin)
- Skin conditioning and moisturizing ingredients: Vitamin C derivative, Vitamin E, Job's tears extract, and others
- Available in refreshing to moist types
- Entry line, cost performance focused
✦ Hada Labo Premium Medicated Penetrating Whitening Lotion
- Active ingredients: Tranexamic Acid + Glycyrrhizic Acid 2K (Double active ingredients)
- Contains two types of hyaluronic acid (Nano HA + HA Na-2)
- Skin conditioning and moisturizing ingredients: Vitamin C derivative, Vitamin E
- Serum-grade rich formula (moist)
- Deep approach to melanocytes
Ingredients
| Ingredient name | Category | Main functions |
|---|---|---|
| Whitening active Tranexamic Acid (White Tranexamic Acid®) | Whitening active ingredient | Suppresses the initial stage of melanin production (inflammatory substance production) to prevent spots and freckles. Also has anti-inflammatory effects that prevent redness and rough skin caused by UV rays. |
| Anti-inflammatory active Glycyrrhizic Acid 2K | Anti-inflammatory active ingredient | Suppresses inflammation and prevents rough skin and acne. Synergistically blocks spot formation with whitening ingredients. |
| Moisturizing Hydrolyzed Hyaluronic Acid (Nano Hyaluronic Acid) | Moisturizing Ingredient | Particles of hyaluronic acid micro-sized to less than 1/100th penetrate deep into the stratum corneum, delivering moisture from within. |
| Moisturizing Sodium Hyaluronate-2 | Moisturizing Ingredient | Has high water retention capacity, holding 6L of water per gram, widely moisturizing the skin surface and preventing dryness. |
| Skin Conditioning Magnesium Ascorbyl Phosphate (Vitamin C derivative) | Skin Conditioning Moisturizing Ingredient | Penetrates inside the stratum corneum, preventing dryness from UV damage while refining skin texture. |
| Skin Conditioning Vitamin E | Skin Conditioning Moisturizing Ingredient | Improves skin from the outer stratum corneum and prevents dryness caused by UV damage. |
| Concentrated Glycerin, Diglycerin | Moisturizer | Basic moisturizing ingredient that firmly hydrates the skin and prevents dryness. |
| BG (Butylene Glycol) | Moisturizer / Solvent | Helps ingredient penetration and enhances formulation stability and moisturizing power. |
| Pentylene Glycol | Moisturizer / Preservative Aid | Enhances moisturizing effect while improving product preservative performance. |
| PEG (30), PEG-8 | Moisturizer / Emulsifying Aid | Creates a moist feel while aiding ingredient dissolution and stability. |
| POE (24) POP (24) Glyceryl Ether | Emulsifier | Uniformly emulsifies oil and water components to maintain a stable formulation. |
| Lauric Acid POE (20) Sorbitan | Emulsifier | Nonionic surfactant that helps disperse and stabilize ingredients. |
| Carbomer | Thickener | Creates a rich "serum-grade" texture and enhances adhesion to the skin. |
| VP-Styrene Copolymer Emulsion | Film-forming Agent | Forms a thin film on the skin surface to lock in moisture. |
| Phenoxyethanol, Sodium Pyrosulfite | Preservative / Antioxidant | Prevents microbial contamination and oxidative deterioration while stably maintaining product quality. |
| Edetate | Chelating Agent | Chelates metal ions to maintain ingredient stability and quality. |
* Active ingredients: Tranexamic Acid, Dipotassium Glycyrrhizinate / Other ingredients: Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate-2, Magnesium Ascorbyl Phosphate, Vitamin E, BG, Concentrated Glycerin, Diglycerin, Pentylene Glycol, PEG (30), PEG-8, POE (24) POP (24) Glyceryl Ether, Edetate, Lauric Acid POE (20) Sorbitan, VP-Styrene Copolymer Emulsion, Sodium Pyrosulfite, Carbomer, Phenoxyethanol
* Ingredient information is based on Rohto Online Shop and Matsukiyo listings. There may be changes depending on product lot. Please check the latest information in the attached document.
Efficacies and Effects
This product is recognized as a Quasi-drug with the following efficacies and effects.
* This product is not a medicine and is not intended for diagnosis, treatment, or prevention of diseases.
* This product does not remove already formed spots (not a treatment effect).
* "Whitening" means suppressing melanin production to prevent spots and freckles.
* Effects may vary from person to person.
How to Use / Directions
| Items | Contents |
|---|---|
| Usage Timing | Use as the first step in your skincare routine after washing your face. It is recommended to seal in moisture with an emulsion or cream after applying lotion. |
| Recommended Amount | Take an appropriate amount (about the size of a 500-yen coin, approximately 1.5–2mL) in your palm and gently blend over the entire face. You may apply additional layers on areas that feel particularly dry. |
| Basic Usage | ① Use immediately after washing your face ② Take an appropriate amount in the palm ③ Gently blend over the entire face as if wrapping it ④ Use fingertips to blend into detailed areas like around the eyes and nose ⑤ Press in to absorb before proceeding to step ② |
| Variant | Bottle 170mL (JAN: 4987241168491) Refill 170mL (JAN: 4987241168477) * Refreshing type (JAN: 4987241168446) also sold separately |
| Product Name | Rohto HP Quasi-drug Whitening Lotion Ra |
| Manufacturer | Rohto Pharmaceutical Co., Ltd. 1-8-1 Tatsuminishi, Ikuno-ku, Osaka City, Osaka Prefecture TEL: 06-6758-1230 |
Frequently Asked Questions
*Source: Rohto Pharmaceutical official FAQ (https://faq.rohto.com/faq_detail.html?id=1468&category=84&page=1)
*This product is not a medicine.
Brand Story
Restore your natural translucency. The philosophy of Hakuju Premium®
Rohto Pharmaceutical's "Hada Labo®" was born in 2004 under the philosophy of "Perfectly Simple." The concept of removing unnecessary elements and delivering only the essential ingredients to the skin at the highest purity is proven by its achievement of 14 consecutive years as Japan's No.1 in domestic sales volume in the skincare cosmetics category (Intage SRI/SRI+ data).
The vision of Hakuju Premium® is "to aim for the natural translucent skin you inherently have." For example, the uniform skin tone and translucency of skin that has not been damaged by UV rays, like the inside of the upper arm which is less exposed to sunlight—that is the natural skin Rohto Pharmaceutical aims for. Rohto's unique research has revealed that visible spots increase at a rate 2.3 times faster after age 35, making early intervention on melanocytes important. Hakuju Premium® condenses this scientific knowledge into its products.
Also, Hada Labo® places great importance on environmental responsibility and has continued sustainable product development since launching refill packs in 2005, including adopting biomass containers made from plant-derived materials.
Usage Precautions
⚠ Usage Precautions
- Do not use on wounds, swelling, eczema, or other abnormal areas.
- Use with care, paying close attention to any abnormalities on the skin. If redness, swelling, itching, irritation, discoloration (such as white spots), or darkening occurs during or after use when exposed to sunlight, discontinue use and consult a dermatologist. Continuing use may worsen symptoms.
- Avoid contact with eyes; if it gets into eyes, rinse immediately with water or lukewarm water. If abnormalities persist, consult an ophthalmologist.
- If it gets on clothing or other items, wash off immediately with water (may cause discoloration or deterioration).
- For external use only. Do not ingest.
Storage Precautions
📦 Storage and Handling Precautions
- After use, close the cap tightly and store.
- Avoid direct sunlight, high temperatures, and low temperatures; store at room temperature.
- Keep out of reach of infants and young children.
- Do not transfer to other containers (may cause misuse or quality changes).
- This product is not classified as an aviation hazardous material under the Aviation Law (follow each airline's regulations for carry-on and checked baggage).
