Boraginol PREMIUM Suppository
Boraginol's highest amount of active ingredients ever
For pain, bleeding, swelling, and itching mainly caused by internal hemorrhoids inside the anus
💊 Product overview
Boraginol PREMIUM Suppository is a Designated Class 2 OTC Drug for hemorrhoids suppository manufactured by Tendo Pharmaceutical Co., Ltd. and sold by Daiichi Sankyo Healthcare. Released in November 2025 as a premium series with the concept of "Boraginol's highest amount of active ingredients ever," it is a dosage form specialized mainly for internal hemorrhoids inside the anus. Five active ingredients comprehensively act on pain, bleeding, swelling, and itching caused by hemorrhoids and anal fissures.
This 5-ingredient formula contains a high concentration of steroid ingredient prednisolone acetate ester (Weak class) and local anesthetic lidocaine, plus non-steroidal anti-inflammatory glycyrrhetinic acid, tissue repair allantoin, and blood circulation promoting vitamin E acetate. The base uses oil-based hard fat that melts quickly at body temperature (about 37°C), allowing the melted medicine to spread inside the anus and directly reach the affected area.
⭐ 4 features
Compared to the conventional Boraginol A series, this premium formula contains more steroid ingredients, lidocaine, and vitamin E acetate. Five active ingredients, including the non-steroidal anti-inflammatory glycyrrhetinic acid, effectively act on painful internal hemorrhoids and anal fissures.
The oil-based base "hard fat" begins to melt quickly at rectal temperature (about 37°C), spreading inside the anus and delivering medicine directly to the affected area. It has low irritation, is easy to insert, protects the injured area, and helps smooth bowel movements.
By inserting the suppository into the rectum, it delivers medicine to internal hemorrhoids and internal anal fissures that are hard to reach from outside the anus. This dosage form addresses inflammation, bleeding, swelling, and itching from inside the body.
By combining two types of anti-inflammatory approaches: steroidal anti-inflammatory ingredient prednisolone acetate ester and non-steroidal anti-inflammatory ingredient glycyrrhetinic acid, it comprehensively calms inflammation, swelling, and itching of hemorrhoids.
🔬 Ingredients and amounts (per 1 piece 1.75g)
| Ingredient name | Amount | Function | Classification |
|---|---|---|---|
| Prednisolone Acetate Ester | 1mg | Suppresses inflammation and relieves bleeding, swelling, and itching | Steroidal anti-inflammatory ingredient (Weak class) |
| Lidocaine | 60mg | Calms local pain and itching | Local anesthetic ingredient |
| Glycyrrhetinic Acid | 10mg | Relieves inflammation causing itching and pain | Non-steroidal anti-inflammatory ingredient |
| Allantoin | 20mg | Helps wound healing and repairs tissue | Tissue repair ingredient |
| Vitamin E acetate (Tocopherol Acetate) |
60mg | Improves peripheral blood circulation and helps relieve congestion | Blood circulation promoting ingredient |
*Hard fat is an oil-based base that melts quickly at body temperature and helps spread the medicine inside the anus. It has low irritation and is easy to insert.
✅ Indications and effects
Effective in relieving the following symptoms of hemorrhoids and anal fissures.
Indications: Hemorrhoids (internal and external hemorrhoids) and anal fissures. This product (suppository) is mainly suitable for hemorrhoids inside the anus (internal hemorrhoids). *No disinfectant effect (if disinfection is needed, consider ointment or suppository ointment (for application)).
📋 Dosage and administration
| Age | Amount per use | Number of uses per day | How to use |
|---|---|---|---|
| Adults (15 years and older) | 1 piece | 1 to 2 times | Insert into the anus excluding the wrapping |
| Under 15 years old | Do not use | ||
📊 Boraginol PREMIUM Series Dosage Form Comparison
Please choose the dosage form according to the hemorrhoid location, symptoms, and lifestyle.
| Comparison items |
This product
PREMIUM Suppository |
PREMIUM Ointment |
PREMIUM Suppository ointment |
|---|---|---|---|
| Drug classification | Designated Class 2 OTC Drug | Designated Class 2 OTC Drug | Designated Class 2 OTC Drug |
| Dosage form | Suppository (individually wrapped) | Ointment (tube) | Suppository ointment (with individually wrapped nozzle) |
| Number of active ingredients | 5 types | 6 types | 6 types |
| Steroid (Prednisolone Acetate Ester) |
✅ 1mg/1.75g | ✅ 1mg/1g | ✅ 1mg/2g |
| Lidocaine (Local Anesthetic) |
60mg/1.75g | 30mg/1g | 60mg/2g |
| Glycyrrhetinic Acid (Non-Steroidal Anti-Inflammatory) |
✅ 10mg/1.75g | — | ✅ 10mg/2g |
| Chlorpheniramine Maleate Salt (Antihistamine) |
— | ✅ 2mg/1g | — |
| Isopropyl Methylphenol (Sterilization and Disinfection) |
— | ✅ 1mg/1g | ✅ 2mg/2g |
| Allantoin (Tissue repair) |
20mg/1.75g | 10mg/1g | 20mg/2g |
| Vitamin E acetate (Promotes blood circulation) |
60mg/1.75g | 30mg/1g | 60mg/2g |
| Disinfectant effect | — | ✅ Yes | ✅ Yes (only when applying) |
| Suitable hemorrhoid location | Mainly internal hemorrhoids (Internal hemorrhoids) |
Mainly outside near the anus (External hemorrhoids and anal fissures) |
Inside and outside Suitable for both |
| Usage | Insert into anus 1 to 2 times a day |
Apply 1 to 3 times a day |
Insert: 1 to 2 times a day Apply: 1 to 3 times a day |
| Base and texture | Hard fat Melts and spreads at body temperature |
Oil ointment Apply from tube |
Oil-based base Hygienic insertion with nozzle |
| Carrying and storage | Melts at body temperature Recommended to store in a cool place |
Easy storage in a tube No temperature control needed |
Convenient individual packaging for carrying No temperature control needed |
| For people like this | For internal hemorrhoids from inside the body Want to approach firmly |
For external hemorrhoids and anal fissures Want to apply directly and disinfect |
Difficult to determine inside or outside, For those who prioritize ease of use even when out |
❓ Frequently Asked Questions (Official Q&A)
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Which should I choose: suppository, ointment, or suppository ointment?Suppositories are mainly suitable for internal hemorrhoids inside the anus, ointments for external hemorrhoids and anal fissures near the anus. Suppository ointments can be used for both inside and outside, but use only on one side per application (do not use what was applied externally for insertion).
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When is the best time to use the suppository?If using twice a day, the recommended times are morning (after bowel movement) and evening (after bathing or before bed). After bowel movements or bathing, the affected area is clean, making it easier for the medicine to penetrate.
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The suppository melts and comes out quickly; does it still work?Suppositories naturally settle in the rectal ampulla. The melted medicine spreads to reach the affected area, so some effect can be expected even if some liquid comes out. However, if insertion is insufficient, the suppository may come out as is. Please make sure to insert it fully.
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Is the steroid included a strong ingredient?The prednisolone acetate included is classified as a weak class steroid topical medicine. It is a synthetic ingredient based on adrenal cortex hormone, but if used properly, there is no need for excessive concern. However, avoid long-term use, and if no improvement is seen after about 10 days, consult a doctor.
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Can I use this with other OTC hemorrhoid medicines?Concomitant use with other hemorrhoid treatments is not recommended. There may be overlapping ingredients, and this product is designed to be effective when used alone. There are no prohibitions or restrictions on using it with other OTC drugs besides hemorrhoid treatments, but if concerned, please consult a pharmacist or registered seller.
Boraginol is a leading Japanese hemorrhoid treatment brand manufactured by Tento Pharmaceutical Co., Ltd. For many years, it has supported people troubled by hemorrhoids and anal fissures with a wide range of products from topical to oral medications.
In November 2025, aiming to better address symptoms, the Boraginol PREMIUM series was launched. It is available in three forms: suppository, ointment, and suppository ointment, all containing the largest amount of active ingredients in Boraginol's history. The premium suppository maximizes the suppository's characteristic of directly approaching internal hemorrhoids from inside the body, quickly melting at body temperature and spreading with a hard fat oil-based base, ensuring reliable drug delivery to the affected area.
Tento Pharmaceutical Co., Ltd. has specialized in the hemorrhoid field for many years, continuously supporting users' comfortable daily lives.
⚠️ Usage and storage precautions
- Those who have had allergic reactions to this product or its ingredients
- Those with suppurating affected areas
- Children under 15 years old
- Those receiving medical treatment
- Those who are pregnant or think they might be pregnant
- Those who are breastfeeding (consult your primary doctor before use)
- Those who have had allergic reactions to medicines
- Do not use for a long period.
- If symptoms do not improve after about 10 days of use, stop use and consult a doctor, pharmacist, or registered seller.
- Use only on the anus.
- If side effects such as rash, itching, or worsening irritation occur, stop use and consult a doctor.
- Avoid direct sunlight and store in a cool place. Since suppositories melt at body temperature, avoid storing them in high-temperature places (such as inside a car in summer or places exposed to direct sunlight).
- If it becomes too soft, cool it for a while before use.
- Keep out of reach of children.
- Do not use the product after the expiration date.
- Do not transfer to another container.