







Smile 40 Mediclear DX
Eye drops specialized for eye troubles that care for itching and redness with double herbal ingredients
For these people and situations
Product overview
Smile 40 Mediclear DX is a Class 2 OTC Drug eye drop specialized in caring for itching and redness, part of Lion Corporation’s Smile DX series. It contains two herbal-derived anti-inflammatory ingredients, berberine chloride hydrate and dipotassium glycyrrhizinate, directly supporting eye resistance. Additionally, it includes seven active ingredients in total for itch suppression, redness removal, and metabolism promotion to comprehensively care for eye trouble symptoms.
Vitamin A (10,000 units) acts on the cornea to retain tears and support corneal repair. Features a cool type with refreshing level 4 sensation for a crisp eye drop feel. Contains no preservatives (such as benzalkonium chloride), with preservative effect ensured by Lion’s unique technology. Please consult a doctor, pharmacist, or registered seller if you have any questions.
Product features
Double herbal-derived anti-inflammatory ingredients
Berberine chloride hydrate + Dipotassium glycyrrhizinateContains two types of herbal-derived ingredients with antibacterial and anti-inflammatory effects. Directly supports eye resistance against troubles like itching and redness.
Immediate care for itch suppression and redness removal
Chlorpheniramine maleate + Tetrahydrozoline hydrochlorideContains antihistamine ingredients to care for eye itching and vasoconstrictor ingredients to remove redness. Directly addresses bothersome itching and redness symptoms.
Vitamin A included to support corneal repair
Retinyl palmitate 10,000 unitsContains Vitamin A that acts directly on the cornea. Retains tears and supports corneal repair, addressing the root causes of itching and redness.
Preservative-free, refreshing level 4
Lion’s unique preservative power technologyNo preservatives such as benzalkonium chloride are added; Lion’s unique technology ensures preservative effect. Provides a refreshing level 4 cool sensation for a crisp eye drop experience.
Active ingredients (per 100mL)
| Ingredient name | Content amount | Action classification |
|---|---|---|
| Retinyl palmitate (Vitamin A) | 10,000 units | Corneal repair |
| d-α-Tocopheryl acetate (natural Vitamin E) | 0.05g | Metabolism promotion |
| Pyridoxine hydrochloride (Vitamin B6) | 0.08g | Metabolism promotion |
| Chlorpheniramine maleate | 0.03g | Itch suppression |
| Tetrahydrozoline hydrochloride | 0.02g | Redness removal |
| Berberine chloride hydrate | 0.01g | Antibacterial and anti-inflammatory (herbal medicine) |
| Dipotassium glycyrrhizinate | 0.25g | Anti-inflammatory (herbal medicine) |
Efficacy and effects
Dosage and administration
| Amount per application | Number of daily applications |
|---|---|
| 1 to 3 drops | 3 to 6 times |
・When used by children, use under the guidance and supervision of a guardian.
・Do not let the tip of the container touch your eyes, eyelids, or eyelashes (this can cause contamination or foreign matter intrusion). Do not use if the solution is cloudy.
・Do not use while wearing soft contact lenses.
・For ophthalmic use only.
Smile DX Series Comparison
| Comparison items | 【Smile 40 MediClear DX】 |
Smile The Medical A DX |
Smile 40 Premium DX |
Smile The Medical A DX Contact |
|---|---|---|---|---|
| Classification | Class 2 OTC Drug | Class 3 OTC Drug | Class 2 OTC Drug | Class 3 OTC Drug |
| Main target symptoms | Itching, redness, inflammation, blurriness | Dryness, fatigue from overuse, blurriness | Eye fatigue, blurriness, redness, itching | Dryness, fatigue from overuse, blurriness |
| Number of active ingredients | 7 types | 3 types | 10 types | 4 types |
| Vitamin A content | 10,000 units | 50,000 units (maximum amount) | 50,000 units (maximum amount) | 50,000 units (maximum amount) |
| Herbal-derived anti-inflammatory ingredients | Berberine chloride hydrate + dipotassium glycyrrhizinate (double formulation) | None | None (contains epsilon-aminocaproic acid) | None |
| Itch relief ingredient | Chlorpheniramine maleate | None | Chlorpheniramine maleate | None |
| Redness relief ingredient | Tetrahydrozoline hydrochloride | None | Tetrahydrozoline hydrochloride | None |
| Cooling sensation | Level 4 (Cool) | Level 0 (Mild) | Level 4 (Cool) | Level 0 (Mild) |
| Use while wearing contacts | Hard lenses only | Hard lenses only | Hard lenses only | Compatible with all contacts (except colored CL) |
| Preservative-free | Additive-free | Additive-free | Additive-free | Additive-free |
| Recommended for | For those especially troubled by itching and redness who want care with herbal-derived ingredients | For those whose main concerns are dryness and fatigue and are looking for eye drops that don’t sting | For those concerned about a wide range of symptoms from eye fatigue to redness and itching | For those who want to easily apply eye drops while wearing contacts |
🌱 Brand Story
Lion Corporation’s "Smile" is an ophthalmic drug brand loved in Japan for many years. Our unique "Cornea Research Institute" continues to study the cornea, the key to eye health, and the DX series realizes the concept of "healing from the cornea." MediClear DX is one product in the series focusing on care for symptoms like itching and redness, blending herbal ingredients based on traditional Eastern medicine with a modern eye drop formulation.
- Consult a doctor, pharmacist, or registered seller before use: Those receiving medical treatment. Those who have had allergic reactions to medicines. Those with severe eye pain. Those diagnosed with glaucoma.
- If rash, redness, itching, eye redness, itching, swelling, stinging, or pain occurs after use, stop immediately and consult a doctor, pharmacist, or registered seller.
- If eye blurriness does not improve or symptoms do not get better after 5 to 6 days of use, stop using and consult a doctor, pharmacist, or registered seller.
- Do not use while wearing soft contact lenses.
- Excessive use may cause abnormal glare or even lead to redness.
- Do not let the tip of the container touch your eyes, eyelids, or eyelashes. Do not use if the solution is cloudy.
- Avoid direct sunlight and store in a cool place as much as possible.
- Keep out of reach of children.
- Do not transfer to other containers (this may cause misuse or change the quality).
- Do not use products past their expiration date.
- Please use as soon as possible after opening.




















































































