Nichinichi pharmaSKU: 4515158190726

Protesan S3

¥59,162 JPY

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31 packets 186 packets

Product variants

Protesan S3

¥59,162 JPY

selection

31 packets 186 packets

Nichinichi Pharmaceutical · Highest concentration in the Protesan series

Protesan S3

Patented lactic acid bacteria material FK-23 · Equivalent to 12 trillion per packet · Equivalent to 1,200L of yogurt

🦠 Equivalent to 12 trillion per packet 🥛 Equivalent to 1,200L of yogurt ✅ Allergen-free 🏆 FK-23 Patent achievements

🔬 What is the lactic acid bacteria material "FK-23" used in Protesan S3?

FK-23 is a lactic acid bacteria material derived from the human intestinal bacteria Enterococcus faecalis, uniquely selected by Nichinichi Pharmaceutical and heat-treated to maximize functionality. The heat-sterilized bacterial bodies are efficiently absorbed from the Peyer's patches in the small intestine and also serve as nourishment for the diverse resident bacteria in the gut flora. It is characterized by the ability to concentrate an amount of bacteria impossible with live bacteria into one packet and holds six patents in the health and beauty fields. It has been researched and manufactured for over 30 years since the company's founding in 1987.

🏆

Three times Protesan S, highest concentration in the series!

Protesan S3 was developed based on Nichinichi Pharmaceutical's long-selling product "Protesan S" (equivalent to 4 trillion per packet) in response to customer requests for "wanting to take more." The lactic acid bacteria amount per packet is tripled to 12 trillion equivalent, and it is a new type that dissolves in water. It boasts the highest concentration of lactic acid bacteria material in the Protesan series (Stick Granules type).

🟡 About the product

"Protesan S3" is the highest concentration product in the long-selling "Protesan" series manufactured by Nichinichi Pharmaceutical for over 30 years since its founding in 1987. It contains an ultra-high concentration of lactic acid bacteria material FK-23 equivalent to 12 trillion per packet (3.3g), which corresponds to 1,200 liters of yogurt.

Ingredients are only FK-23 (heat-treated lactic acid bacteria), maltose, and thickener (CMC). No fragrances or sweeteners used. The formula is allergen-free, containing none of the 28 specified food allergens. Suitable for a wide range of ages from infants to Elderly.

Dissolvable type: dissolve one packet (3.3g) in about 100mL of water and consume. Recommended intake is 1 to 6 packets per day. Can also be mixed into juice, tea, miso soup, or yogurt.

✨ Four features

🦠

Equivalent to 12 trillion per packet, highest concentration

Contains three times the amount of lactic acid bacteria as Protesan S in just one packet. Contains the highest concentration of FK-23 in the Protesan series (Stick Granules).

✅

Free from all 28 specified allergens

Completely allergen-free formula containing none of the 28 specified food allergens. No fragrances or sweeteners used, so a wide range of people can consume it safely.

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Dissolvable type to drink by mixing in water

A new type to dissolve in about 100mL of water before drinking. Can also be mixed into juice, tea, miso soup, or yogurt. Designed to be easy to drink with almost no taste or smell.

👨👩👧👦

Supports a wide range of ages and purposes

Suitable for all ages from infants to Elderly. Intake can be adjusted from 1 to 6 packets per day, allowing use according to your condition and purpose.

🌟 Expected health support

🦠 Supplementation of high-concentration FK-23 lactic acid bacteria 🌿 Support for intestinal environment and gut flora 💪 Daily health maintenance 🍃 For those concerned about seasonal and environmental changes 👨👩👧👦 Suitable for infants to Elderly

* This product is a food (lactic acid bacteria-containing food) and is not intended for diagnosis, treatment, or prevention of diseases.

📦 Size variations

📦

31 packets included

Content: 102.3g (3.3g × 31 packets)
About 10 to 31 days supply using 1 to 3 packets per day
For first-time users or
Recommended for trial

JAN: 4515158190726

🏷️

186 packets included

Content: 613.8g (3.3g × 186 packets)
About 62 to 186 days supply using 1 to 3 packets per day
For those who continue use
Save by buying in bulk

JAN: 4515158190559

🔬 Learn about Nichinichi Pharmaceutical's three lactic acid bacteria materials

Nichinichi Pharmaceutical's lactic acid bacteria supplements use three types of lactic acid bacteria materials processed differently. All are made from the same bacteria called Enterococcus faecalis, but their properties and names differ depending on the depth of processing.

🔥

FK-23

Heat treatment only

A material where Enterococcus faecalis is heat sterilized and concentrated. The bacterial bodies remain intact and are absorbed from the Peyer's patches in the small intestine. Used in the Protesan series (B, R, S, S3). Holds six patents.

⚗️

LFK (FK-23 bacterial extract)

Heat treatment + enzyme treatment

A material where FK-23 is further treated with enzymes to dissolve the bacterial cell walls and extract internal components (nucleic acids, vitamins, minerals, etc.). Used in the Chisa series (Ferna and White). Holds six patents.

✨

MK-116

Both FK-23 and LFK processed

A unique special processed lactic acid bacteria material from Nichinichi Pharmaceutical that combines the characteristics of both FK-23 and LFK. Used in Protesan Every II.

📊 Nichinichi Pharmaceutical Lactic Acid Bacteria Supplements Full Series Comparison

Compare the full lineup of Nichinichi Pharmaceutical's lactic acid bacteria supplements including Protesan S3. Choose the product that suits you based on differences in materials, concentration, and formulation.

Comparison items	FK-23 material (heat treatment)				LFK material (heat + enzyme treatment)		MK-116 (FK-23 + LFK)
Comparison items	Protesan B	Protesan R	Protesan S	🟡 Protesan S3 (this product)	Chisa Ferna	Chisa White	Every II
Lactic acid bacteria material	FK-23	FK-23	FK-23	FK-23	LFK	LFK	MK-116
Processing method	Heat treatment only			Heat treatment only	Heat treatment + enzyme treatment		Heat treatment + enzyme treatment (Both FK-23 and LFK)
Amount per packet	300 billion	1 trillion	4 trillion	12 trillion	2.2 trillion	650 billion	1.2 trillion
Yogurt Equivalent	30L	100L	400L	1,200L	220L	65L	120L
Amount per packet	1.0g	1.2g	1.5g	3.3g (dissolvable type)	1.5g	1.0g	1.0g
Quantity	31 packets	62 packets	62 packets	31 packets / 186 packets	30 packets	30 packets	62 packets
Oligosaccharides	✅	✅	✅	—	—	—	✅
Indigestible Dextrin	✅	✅	—	—	—	—	✅
No water intake	✅ Allowed	✅ Allowed	✅ Allowed	❌ Requires dissolution	✅ Allowed	✅ Allowed	✅ Allowed
Allergens	Free	Free	Free	Free	Egg	Egg & Gelatin	Egg

🧭 Which one to choose? — Guide by purpose

🌱 Protesan B — For beginners and children

For first-time FK-23 users, infants, and those with weak health. The mildest concentration starting from 1 packet per day (300 billion). Contains oligosaccharides and dietary fiber for gentle support.

🔵 Protesan R — Standard for daily use

Contains the equivalent of 1 trillion FK-23 per packet. Balanced formula with oligosaccharides and indigestible dextrin. Popular as a standard for daily health and beauty care.

🟢 Protesan S — Convenient high-concentration FK-23

Contains the equivalent of 4 trillion FK-23 per packet. Stick Granules type that can be taken as is without dissolving in water. The main high-concentration type in the Protesan series.

🟡 Protesan S3 (this product) — Highest concentration in the series

Contains the equivalent of 12 trillion FK-23 per packet. Three times the concentration of Protesan S. Available in water-soluble types with 31 and 186 packets. Allergen-free and suitable for a wide age range. For those who want to concentrate FK-23 intake to the maximum.

🔵 Chisa Ferna — Simply high-concentration LFK

Contains the equivalent of 2.2 trillion LFK, which is FK-23 further enzyme-treated. Unlike heat-treated FK-23, it allows intake of internal bacterial components. For those who want pure, high-concentration LFK.

🌸 Chisa White — LFK + beauty ingredients together

In addition to LFK, contains beauty ingredients such as collagen, hyaluronic acid, vitamin C, and mandarin powder. For those who want to combine LFK with beauty care. Easy to drink with a yogurt flavor.

🟣 Protesan Every II — Both FK-23 and LFK properties

Contains MK-116 material specially processed with both FK-23 and LFK. Also includes oligosaccharides and indigestible dextrin. For those who want the benefits of both FK-23 and LFK.

Nutrition Facts Per packet (3.3g)

Nutritional Information	Per packet (3.3g)
Calories	11 kcal
Protein	1.7 g
Fat	0.076 g
Carbohydrates	0.94 g
Equivalent Salt Content	0.0024–0.0079 g
Potassium	47–100 mg
Phosphorus	100 mg

💧 Easy Drinking Method (Dissolvable Type)

🥛

Prepare a dry cup

Always use a dry container

📦

Add one packet

Add directly to the cup

💧

Pour about 100mL of water

Water or tea is also fine

🥄

Stir well before drinking

Drink immediately before sedimentation

⚠️ Important: Consuming this product as is (in powder form) can cause it to clump with moisture and pose a choking hazard. Always dissolve in water or another liquid before drinking. Sediment or floating particles may occur but do not affect quality.

💧 Water or lukewarm water 🍵 Tea 🧃 Juice 🍜 Miso Soup 🥛 Yogurt

* Recommended usage: 1 to 6 packets per day. Adjust the amount according to your condition and purpose.

📋 Product Specifications

Product Name	Lactic Acid Bacteria-Containing Food (Powdered Refreshing Drink)
Net Weight	[31 packets] 102.3g (3.3g × 31 packets) JAN: 4515158190726 [186 packets] 613.8g (3.3g × 186 packets) JAN: 4515158190559
Lactic Acid Bacteria Content (per packet)	Equivalent to 12 trillion (1,200L of yogurt)
Daily Recommended Amount	1–6 packets
Ingredients	Lactic acid bacteria (heat-treated) (domestically produced), maltose / thickener (CMC)
Allergens	No use of any of the 28 specified allergenic ingredients (Allergen-Free)
Storage Method	Store in a cool, dry place away from direct sunlight
Country of Manufacture	Japan
Manufacturer	Nichinichi Pharmaceutical Co., Ltd.

✅ Allergen-Free (No use of any of the 28 specified allergenic ingredients)

This product does not contain any of the 28 specified allergenic ingredients (egg, milk, wheat, shrimp, crab, peanuts, buckwheat, walnut, soy, beef, pork, chicken, gelatin, abalone, squid, salmon roe, orange, cashew nuts, kiwi fruit, sesame, salmon, mackerel, banana, peach, yam, apple, almond, matsutake mushroom). Safe for those with food allergies.

Usage Precautions

⚠️ Please check before use

This product is a food (lactic acid bacteria-containing food). It is not a medicine. It is not intended for diagnosis, treatment, or prevention of diseases.
Do not consume as is (in powder form). There is a risk of choking. Always dissolve in water or another liquid before drinking.
Follow the daily recommended amount (1–6 packets) and avoid excessive intake. Consuming large amounts will not cure diseases or improve health further.
If you feel it does not suit your constitution, reduce the amount used or discontinue use.
If you are pregnant, breastfeeding, under medical care, or taking medication, please consult your doctor before use.
Do not consume products past their expiration date.
Keep out of reach of infants and toddlers.
Consume as soon as possible after opening.
Maintain a balanced diet based on staple foods, main dishes, and side dishes.

📦 Storage Precautions

Store in a cool, dry place away from direct sunlight.
Consume as soon as possible after opening.
Keep out of reach of infants and toddlers.