Class 2 OTC DrugEye Drops
Sante Medical Plus Guard EX
Eye drops formulated for eye fatigue and blur related to age, dryness, and similar concerns
✦ With Vitamin A✦ Tear Film Stabilization✦ Focus Adjustment Support✦ Corneal Protection & Moisture Retention
Who It’s For & When to Use
👁
Those concerned about age-related eye strain
When a formula suited to eye fatigue and blur that tend to be more noticeable with age is needed.
💧
Those bothered by dry or stinging eyes
For discomfort linked to dryness, or when eye inflammation associated with dryness is a concern.
🌫️
Those with lingering blur or difficulty seeing clearly
An OTC medicine for eye discomfort accompanied by blur, such as when discharge is excessive.
😣
Those bothered by redness or itching
When the goal is relief of symptoms included in the labeled indications, such as conjunctival hyperemia and itchy eyes.
Product Overview
Sante Medical Plus Guard EX is a Class 2 OTC eye drop formulated for eye fatigue and blur related to age, dryness, and similar concerns. It combines active ingredients including vitamin A and others involved in corneal protection and moisture retention, inflammation control, tissue metabolism, focus adjustment, and relief of itching and redness—making it a convenient choice when eye discomfort is a concern. Read the package insert before use, and consult a physician, pharmacist, or registered seller if symptoms do not improve.
Product Features
01
Vitamin A to help support tear film stability
Tear Film Stabilization
Formulated with retinol palmitate (vitamin A). A key feature is a formula intended to stabilize the tear film when dryness or age-related eye strain is a concern.
02
Supports improvement of focus adjustment
Accommodation
Contains neostigmine methylsulfate in a design intended to help improve near–far focus adjustment. Suited to times when eye fatigue or blur is a concern.
03
Multi-faceted formula for corneal protection, inflammation, redness, and more
Combination Formula
Combines sodium chondroitin sulfate ester for corneal protection and moisture retention, epsilon-aminocaproic acid and related ingredients for inflammation control, plus antihistamine and decongestant components—addressing eye discomfort from multiple angles.
✦
Ingredients that support tissue metabolism
Contains d-α-tocopherol acetate (vitamin E), potassium L-aspartate, and taurine.
✦
Itch- and redness-relieving ingredients
Contains chlorpheniramine maleate and tetrahydrozoline hydrochloride.
✦
Easy-to-use eye drop format
An eye drop type for everyday eye discomfort.
Indications
Eye fatigue
Conjunctival hyperemia
Prevention of eye disease (e.g., after swimming, or when dust or sweat enters the eyes)
Ophthalmia due to ultraviolet or other light
Blepharitis (sore eyelids)
Itchy eyes
Blurred vision (e.g., when eye discharge is excessive)
Dry eyes
Discomfort while wearing hard contact lenses
Dosage and Administration
| Age |
Dose per use |
Times per day |
| Adults (15 years and older) |
1–3 drops per use |
Instill 3–6 times daily |
| Under 15 years |
Do not use |
— |
Strictly follow the dosage and administration. For details on age and dose, and whether use in children is permitted, follow the package insert. When instilling, take care that the tip of the container does not touch the eye, eyelid, or eyelashes. Read the package insert carefully before use, and consult a pharmacist or registered seller if anything is unclear.
⚠️ Precautions for Use
- This product is a Class 2 OTC drug. Always read the package insert before use.
- The following people should consult a physician, pharmacist, or registered seller before use: those under a physician’s care; those who have had allergic symptoms to medicines or similar products; those with the following symptom (severe eye pain); those diagnosed with the following condition (glaucoma).
- If any of the following symptoms appear after use, they may be side effects. Stop use immediately and consult a physician, pharmacist, or registered seller with the package insert: skin (rash/redness, itching); eyes (redness, itching, swelling, pain).
- The following symptoms may occur after use. If they persist or worsen, stop use and consult a physician, pharmacist, or registered seller: stinging, blurred vision.
- Do not use while wearing soft contact lenses (for use related to discomfort while wearing hard contact lenses, confirm within the labeled indications in the package insert).
- Use only as eye drops.
- Follow the stated dosage and administration.
- If symptoms do not improve or worsen, stop use and consult a physician, pharmacist, or registered seller.
📦 Storage Precautions
- Store tightly closed in a cool place away from direct sunlight.
- Keep out of reach of children.
- Do not transfer to another container (may cause misuse or quality changes).
- Do not share with others.
- To maintain quality, avoid unnecessary opening and closing, high temperatures, and freezing.
- Do not use products past their expiration date.
● Features
For stinging※1 and eye inflammation※2 caused by dryness, etc.
Contains the maximum concentration※5 of seven active ingredients※4 including corneal repair and protection components※3
Troublesome eye problems such as stinging※1 and unpleasant eye inflammation※2 may be caused in part by daily damage＊ to the cornea (surface of the eye) due to friction from contact lenses, ultraviolet rays, dryness, and other irritants.
Sante Medical Plus Guard EX contains the maximum concentration※5 of seven active ingredients including flavin adenine dinucleotide sodium (active vitamin B2) which promotes corneal repair, allantoin, panthenol which activates corneal tissue metabolism, and chondroitin sulfate ester sodium which moisturizes and protects the cornea, totaling 10 active ingredients. This eye drop repairs and protects corneal damage＊ and is effective for eye troubles such as eye inflammation※2 and prevention of eye diseases※6.
※1 Discomfort when wearing hard contact lenses
※2 Eye inflammation caused by ultraviolet rays and other light (such as snow blindness)
※3 Flavin adenine dinucleotide sodium (active vitamin B2), allantoin, chondroitin sulfate ester sodium
※4 Flavin adenine dinucleotide sodium (active vitamin B2), chondroitin sulfate ester sodium, neostigmine methyl sulfate, chlorpheniramine maleate, dipotassium glycyrrhizinate, panthenol, allantoin
※5 Maximum concentration according to the standards for approval of general ophthalmic drugs (the approval standards refer to the range of pharmaceuticals established by the Ministry of Health, Labour and Welfare to streamline approval procedures)
※6 After swimming, when dust or sweat gets into the eyes, etc.
＊ Condition where the cornea is inflamed (such as snow blindness) due to ultraviolet rays, etc.
【Class 2 OTC Drug】
●Efficacy/Effects
Eye inflammation caused by ultraviolet rays and other light (such as snow blindness), blepharitis (eyelid inflammation), prevention of eye diseases (such as after swimming, when dust or sweat gets into the eyes), eye fatigue, eye itching, blurred vision (such as when there is a lot of eye discharge), conjunctival hyperemia, discomfort when wearing hard contact lenses
＜Precautions related to Efficacy/Effects＞
●Dosage and Administration
Instill 1 to 3 drops per dose, 5 to 6 times a day.
＜Precautions related to Dosage and Administration＞
●Please observe the following precautions.
(1) Excessive use may cause abnormal glare or worsen redness.
(2) When used by children, use under the guidance and supervision of a guardian.
(3) Do not let the tip of the container touch the eyes, eyelids, or eyelashes (to prevent contamination or clouding of the solution due to eye discharge or bacteria). Do not use if the solution is cloudy.
(4) Do not use while wearing soft contact lenses.
(5) For ophthalmic use only.
●Ingredients/Quantity
Flavin adenine dinucleotide sodium 0.05%
Allantoin 0.3%
Chondroitin sulfate ester sodium 0.5%
Aminoethylsulfonic acid (taurine) 0.5%
Panthenol 0.1%
L-aspartic acid potassium 0.5%
Neostigmine methyl sulfate 0.005%
Chlorpheniramine maleate 0.03%
Dipotassium glycyrrhizinate 0.25%
Tetrahydrozoline hydrochloride 0.01%
〔Additives〕
Epsilon-aminocaproic acid, edetate sodium hydrate, chlorobutanol, geraniol, dextran, sodium hyaluronate, hydroxyethyl cellulose, benzalkonium chloride solution, polysorbate 80, d-borneol, l-menthol, isotonic agent, pH adjuster
＜Precautions related to Ingredients/Quantity＞
This product may sometimes cause a sweet taste in the mouth after instillation. This is due to dipotassium glycyrrhizinate, one of the ingredients, flowing into the mouth through the tear duct, and is not due to any abnormality in quality.
●Dosage Form
Eye drops (external use [ophthalmic and otorhinolaryngologic agent] - liquid)
●Precautions for Use
■Consult
1. Consult a doctor, pharmacist, or registered seller before use if you:
(1) Are receiving treatment from a doctor
(2) Have had allergic reactions to medicines, etc.
(3) Have any of the following symptoms:
Severe eye pain
(4) Have been diagnosed with:
Glaucoma
2. If the following symptoms appear after use, they may be side effects. Stop use immediately and consult a doctor, pharmacist, or registered seller with this document.
［Affected area: Symptoms］
Skin: rash, redness, itching
Eyes: redness, itching, swelling, stinging pain
3. Stop use and consult a doctor, pharmacist, or registered seller with this document if:
(1) Blurred vision does not improve
(2) Symptoms do not improve after 5 to 6 days of use
●Precautions for Storage and Handling
(1) Store tightly closed in a cool place away from direct sunlight. To maintain product quality, do not leave in places that become hot such as inside a car or near heating appliances. Do not use if the container is deformed or the solution leaks or deteriorates due to being left in a hot place.
(2) Keep out of reach of children.
(3) Do not transfer to other containers. (This may cause misuse or change in quality.)
(4) Do not share with others.
(5) Do not use products past the expiration date. Even within the expiration date, use as soon as possible after opening.
(6) Depending on storage conditions, crystals of ingredients may form yellow deposits around the eye dropper tip or inside the cap. In such cases, gently wipe with clean gauze before use.
(7) The yellow color of this product is due to flavin adenine dinucleotide sodium (active vitamin B2). If the solution spills during instillation and stains clothing, wash immediately with water.
