Class 3 OTC DrugEye Drops
Sante de U Plus E Alpha
Eye drops formulated with a focus on ciliary muscle fatigue to ease eye strain, redness, blurred vision, and more
✦ Contains vitamin B12✦ Contains natural vitamin E✦ 5 active ingredients✦ Also for discomfort while wearing hard contacts
For people like this · Situations like these
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Those concerned about eye strain
When eyes tire easily from prolonged screen work, reading, and similar activities
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Those concerned about conjunctival redness or blurred vision
When eyes are bloodshot or vision is blurred due to excess discharge
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Those concerned about itching or eyelid sores
For itchy eyes or symptoms of blepharitis (sore eyelids)
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Those with discomfort while wearing hard contacts
When you want to ease discomfort while wearing hard contact lenses
Product Overview
Sante de U Plus E Alpha is an eye drop formulated with a focus on excessive fatigue of the ciliary muscle, considered one factor in eye strain. It combines five active ingredients: cyanocobalamin (vitamin B12), which acts on the ciliary muscle to help restore nerve function in the eyes; d-α-tocopherol acetate (natural vitamin E), intended to help maintain peripheral blood flow; neostigmine methylsulfate; chlorpheniramine maleate; and dipotassium glycyrrhizinate. Use for officially indicated symptoms and situations such as eye strain, conjunctival hyperemia, blurred vision, itching, and prevention of eye disease.
Product Features
01
Formulation focused on the ciliary muscle
Vitamin B12
To address overuse of the ciliary muscle—considered one factor in eye strain—cyanocobalamin (red vitamin B12) is included to help restore nerve function in the eyes.
02
Contains natural vitamin E
Blood flow support
Formulated with d-α-tocopherol acetate (natural vitamin E), intended to help maintain blood flow in peripheral vessels.
03
Five active ingredients for multiple eye discomforts
5 ingredients
Combines active ingredients that address eye strain, redness, itching, and more—including neostigmine methylsulfate, the antihistamine chlorpheniramine maleate, and dipotassium glycyrrhizinate.
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While wearing hard contact lenses
Can also be used for discomfort while wearing hard contact lenses (do not use while wearing soft contact lenses).
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Also for eye disease prevention situations
Can be used in situations included in the official indications for eye disease prevention, such as after swimming or when dust or sweat gets in the eyes.
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A sweet taste may be noticed after instillation
This is caused by dipotassium glycyrrhizinate flowing into the mouth via the tear ducts and does not indicate a quality issue.
Indications
Eye strain
Prevention of eye disease (e.g., after swimming, when dust or sweat gets in the eyes)
Conjunctival hyperemia
Blurred vision (e.g., when there is excess eye discharge)
Itchy eyes
Blepharitis (sore eyelids)
Ophthalmia due to ultraviolet or other rays (e.g., snow blindness)
Discomfort while wearing hard contact lenses
Dosage and Administration
| Age |
Dose per use |
Times per day |
| Adults, children, etc. (no age categories stated in the directions) |
1–3 drops per use |
Instill 5–6 times daily |
When used in children, use under the guidance and supervision of a guardian. Do not let the tip of the container touch the eye, eyelid, or eyelashes. Do not use if the solution is cloudy. Do not use while wearing soft contact lenses. Use only as eye drops.
❓ Frequently Asked Questions
QIs a sweet taste in the mouth after instillation abnormal?
AAfter using this product, you may sometimes notice a sweet taste in the mouth. This is caused by one of the ingredients, dipotassium glycyrrhizinate, flowing into the mouth via the tear ducts and is not due to any quality issue.
QCan I use it while wearing soft contact lenses?
ADo not use while wearing soft contact lenses. It can be used for discomfort while wearing hard contact lenses.
QWhy are the solution and container red?
AThe red color of this product comes from vitamin B12 (cyanocobalamin). Depending on storage conditions, red crystals of the ingredient may form around the dropper tip or inside the cap. In that case, gently wipe with clean gauze before use. If the solution spills during use and stains clothing, wash immediately with water.
QWhen should I consult someone about symptoms?
AConsult a physician, pharmacist, or registered seller before use if you are receiving medical treatment, have previously experienced allergic symptoms to medicines, have severe eye pain, or have been diagnosed with glaucoma. If symptoms such as skin rash/redness/itching, or eye redness/itching/swelling/stinging pain appear after use, discontinue use and consult. Also discontinue use and consult if blurred vision does not improve, or if symptoms do not improve after about 2 weeks of use.
⚠️ Precautions for Use
- Consult a physician, pharmacist, or registered seller before use if: you are receiving medical treatment; you have previously experienced allergic symptoms to medicines; you have severe eye pain; or you have been diagnosed with glaucoma.
- Because side effects may occur, if any of the following symptoms appear after use, immediately discontinue use and consult a physician, pharmacist, or registered seller with this document. Skin: rash/redness, itching / Eyes: redness, itching, swelling, stinging pain.
- In the following cases, discontinue use and consult a physician, pharmacist, or registered seller with this document: if blurred vision does not improve; if symptoms do not improve after about 2 weeks of use.
- When used in children, use under the guidance and supervision of a guardian.
- Do not let the tip of the container touch the eye, eyelid, or eyelashes (eye discharge or bacteria may contaminate or cloud the solution). Do not use if the solution is cloudy.
- Do not use while wearing soft contact lenses.
- Use only as eye drops.
📦 Storage Precautions
- Store tightly capped in a cool place away from direct sunlight. Do not leave in high-temperature locations such as inside a car or near heating appliances. Do not use products left in high-temperature locations, as the container may deform and leak, or the quality of the solution may deteriorate.
- Store out of reach of children.
- Do not transfer to another container. (This may cause misuse or a change in quality.)
- Do not share with others.
- Do not use products past the expiration date. Even within the expiration date, use as soon as possible after opening.
- Depending on storage conditions, red crystals of the ingredient may form around the dropper tip or inside the cap. In that case, gently wipe with clean gauze before use.
- The red color of this product comes from vitamin B12 (cyanocobalamin). If the solution spills during use and stains clothing, wash immediately with water.
● Features
Eye fatigue is largely caused by excessive strain (overuse) of the "ciliary muscle" that supports the crystalline lens.
Sante Dou Plus E Alpha is an eye drop that contains five active ingredients, including red vitamin B12, which acts directly on the ciliary muscle to restore eye nerve function, and natural vitamin E, which improves peripheral blood flow. It is effective for improving eye fatigue and preventing eye diseases. Please use it to support your "healthy pupils" lifestyle.
【Class 3 OTC Drug】
● Efficacy/Effects
Eye fatigue, prevention of eye diseases (such as after swimming or when dust or sweat gets into the eyes), conjunctival congestion, blurred vision (such as when there is a lot of eye discharge), eye itching, blepharitis (inflammation of the eyelids), eye inflammation caused by ultraviolet or other rays (such as snow blindness), discomfort when wearing hard contact lenses
＜Precautions related to Efficacy/Effects＞
● Dosage and Administration
Instill 1 to 3 drops per application, 5 to 6 times a day.
＜Precautions related to Dosage and Administration＞
● Please observe the following precautions.
(1) When using for children, use under the guidance and supervision of a guardian.
(2) Do not let the tip of the container touch the eyes, eyelids, or eyelashes (to prevent contamination or clouding of the solution due to eye discharge or bacteria). Do not use if the solution becomes cloudy.
(3) Do not use while wearing soft contact lenses.
(4) Use only for eye drops.
● Ingredients/Quantity
Cyanocobalamin 0.015%
d-α-Tocopherol acetate 0.02%
Neostigmine methyl sulfate 0.002%
Chlorpheniramine maleate 0.01%
Dipotassium glycyrrhizinate 0.1%
〔Additives〕
Aminocaproic acid, edetate sodium hydrate, chlorobutanol, benzalkonium chloride solution, polyoxyethylene hardened castor oil, d-borneol, l-menthol, isotonic agent, pH adjuster
＜Precautions related to Ingredients/Quantity＞
This product may sometimes cause a sweet taste in the mouth after instillation. This is due to dipotassium glycyrrhizinate, one of the ingredients, flowing into the mouth through the tear duct, and is not due to any abnormality in quality.
● Dosage Form
Eye drops (external use [ophthalmic and otorhinolaryngologic agent] - liquid)
● Precautions for Use
■ Consult
1. Consult a doctor, pharmacist, or registered seller before use if you:
(1) Are receiving medical treatment from a doctor
(2) Have had allergic reactions to medicines
(3) Have any of the following symptoms:
Severe eye pain
(4) Have been diagnosed with:
Glaucoma
2. If any of the following symptoms appear after use, stop using immediately and consult a doctor, pharmacist, or registered seller with this document, as they may be side effects.
［Affected area: Symptoms］
Skin: rash, redness, itching
Eyes: congestion, itching, swelling, stinging pain
3. Stop use and consult a doctor, pharmacist, or registered seller with this document if:
(1) Blurred vision does not improve
(2) Symptoms do not improve after about 2 weeks of use
●Precautions for Storage and Handling
(1) Store tightly closed in a cool place away from direct sunlight. To maintain product quality, do not leave it in places that become hot, such as inside a car or near heating appliances. Do not use if the container is deformed or the solution leaks or deteriorates due to exposure to high temperatures.
(2) Keep out of reach of children.
(3) Do not transfer to other containers. (This may cause misuse or quality changes.)
(4) Do not share with others.
(5) Do not use products past the expiration date. Even within the expiration date, use as soon as possible after opening.
(6) Depending on storage conditions, crystals of ingredients may appear red around the dropper tip or inside the cap. In such cases, gently wipe with clean gauze before use.
(7) The red color of this product is due to vitamin B12 (cyanocobalamin). If the solution spills during instillation and stains clothing, wash immediately with water.
