Hada Labo Shirojyun
Medicated Whitening Lotion
For clear, bright skin with White Tranexamic Acid.
Moisturizing and whitening in one bottle.
Product Overview
Hada Labo Shirojyun Medicated Whitening Lotion is a Quasi-drug skincare lotion from Rohto Pharmaceutical's "Hada Labo®" series, developed under the concept of "Perfect Simple." Renewed and relaunched in March 2024, it contains double active ingredients: whitening agent White Tranexamic Acid® and skin-soothing Allantoin.
Contains two moisturizing ingredients, Nano hyaluronic acid (Hydrolyzed hyaluronic acid) and Hyaluronic acid Na-2, to deliver deep hydration. Additionally, skin conditioning ingredients such as Vitamin C derivative (Vitamin C phosphate Mg), Vitamin E, Job's tears extract (Coix lacryma-jobi extract), and Fermented Job's tears liquid support smooth, translucent skin.
Formulated to be mildly acidic, fragrance-free, colorant-free, mineral oil-free, alcohol-free, and paraben-free. Patch tested and non-comedogenic tested for sensitive skin (does not suit everyone).
Four features
Double whitening active ingredients for translucency
Unique White Tranexamic Acid® suppresses melanin production to prevent spots and freckles while creating a clear, bright complexion free of dullness. This ingredient is recognized for efficacy and effects as a Quasi-drug.
Prevents rough skin for healthy skin
Active ingredient Allantoin soothes skin inflammation and prevents acne and rough skin. Supports a healthy skin environment that is less prone to irritation while aiming for whitening.
Seals in moisture with two types of hyaluronic acid
Ultra-fine particle Nano hyaluronic acid delivers moisture deep into the stratum corneum, and Hyaluronic acid Na-2 firmly retains moisture on the skin surface. Achieves fresh, plump skin.
Smooth with skin conditioning and moisturizing ingredients
Vitamin C phosphate Mg (Vitamin C derivative), Vitamin E, Job's tears extract (Coix lacryma-jobi extract), and Fermented Job's tears liquid refine skin texture and lead to smooth, translucent skin.










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Main Ingredients
| Ingredient Name | Category | Main Functions |
|---|---|---|
| Active Tranexamic acid (White Tranexamic Acid®) | Whitening active ingredient | Suppresses melanin production to prevent spots and freckles |
| Active Allantoin | Anti-inflammatory active ingredient | Soothes skin inflammation and prevents acne and rough skin |
| Moisturizing Hydrolyzed hyaluronic acid (Nano hyaluronic acid) | Moisturizing ingredients | Ultra-fine particles penetrate deep into the stratum corneum to deliver moisture |
| Moisturizing Hyaluronic acid Na-2 | Moisturizing ingredients | Keeps skin surface moisturized and prevents dryness |
| Skin conditioning Vitamin C phosphate Mg (Vitamin C derivative) | Skin conditioning ingredients | Refines skin texture for brighter, smoother skin |
| Skin conditioning Vitamin E | Skin conditioning ingredients | Protects skin from oxidative stress and conditions skin condition |
| Skin conditioning Job's tears extract (Coix lacryma-jobi extract) | Plant-based skin conditioning ingredients | Refines skin texture and improves smoothness |
| Skin conditioning Fermented Job's tears liquid | Plant-based skin conditioning ingredients | Ingredients produced during fermentation smooth and condition the skin |
| BG (Butylene glycol) | Moisturizers and solvents | Helps ingredient penetration and retains moisture |
| DPG (Dipropylene glycol) | Moisturizers and solvents | Improves formulation stability and moisture retention |
| Sugar squalane | Emollient ingredients | Provides soft moisture to the skin and supports barrier function |
| Tri(caprylic/capric acid) glycerin | Emollient ingredients | Enhances smooth texture and skin compatibility |
| POE hardened castor oil | Emulsifier | Emulsifies and stabilizes ingredients evenly |
| Phenoxyethanol | Preservative | Preserves product quality and prevents microbial contamination |
| Citric acid, Sodium citrate | pH Adjusters | Keeps the product mildly acidic to reduce skin irritation |
*Active ingredients: Tranexamic acid, Allantoin / Other ingredients: Hydrolyzed hyaluronic acid, Hyaluronic acid Na-2, Vitamin C phosphate Mg, Vitamin E, Job's tears extract, Fermented Job's tears liquid, BG, DPG, Sugar squalane, Tri(caprylic/capric acid) glycerin, POE hardened castor oil, Phenoxyethanol, Anhydrous citric acid, Benzoate salts, Edetate salts, Citric acid, Sodium citrate, etc.
Efficacy and Effects
This product is recognized as a Quasi-drug with the following efficacy and effects.
(Based on the attached document and product labeling)
*This product is not a medicine and is not intended for diagnosis, treatment, or prevention of diseases. *It does not have the effect of removing already formed spots (no therapeutic effect).
How to Use / Directions
| Items | Contents |
|---|---|
| Usage Timing | Use after washing your face as the first step of skincare. It is recommended to use lotion → emulsion or gel in that order. |
| Recommended Amount | Take a 500-yen coin size amount (about 1.5–2mL) into your palm and gently apply over the entire face. You may layer on areas prone to dryness. |
| Basic Usage | ① Take an appropriate amount into the palm ② Spread evenly over the entire face by cupping with both hands ③ Gently blend into small areas like around the nose and eyes with fingertips ④ Seal in moisture with emulsion or gel afterward |
| Variants and Volume | 170mL Bottle (JAN: 4987241157549) 170mL Refill (JAN: 4987241157556) 400mL Pump (JAN: 4987241194476) *Available in refreshing type and moist type |
| Product Name | Rohto H Quasi-drug Whitening Lotion La |
Frequently Asked Questions
*Source: Rohto Pharmaceutical official FAQ (https://faq.rohto.com/faq_detail.html?id=1468&category=84&page=1)
*Source: Based on Rohto Pharmaceutical official product page and Rohto online shop information
Brand Story
Hada Labo® born from the philosophy of "Perfect Simple"
Hada Labo® was born in 2004 under Rohto Pharmaceutical Co., Ltd. with the concept of "Perfect Simple", which means "removing unnecessary ingredients and delivering only the essential ingredients to the skin in minimal amounts and highest purity." It is also known for its development story where young staff got hints from ingredient cosmetics at drugstores and commercialized the product in just six months. It gained explosive support immediately after launch and has grown into a national brand boasting 14 consecutive years as Japan's No.1 in domestic sales volume in the skincare cosmetics category (Intage SRI/SRI+ data).
The Hada Labo Shirojyun series is a Quasi-drug whitening line born from Hada Labo®. It centers on Rohto Pharmaceutical's unique White Tranexamic Acid® as the core ingredient, aiming to achieve both clarity and moisture simultaneously. The formula was renewed in spring 2024 to provide higher whitening effects and skin irritation prevention. As part of environmental efforts, since launching refill products in 2005, the series has continued sustainable product development, including the introduction of biomass containers (plant-derived).
Usage Precautions
⚠ Usage Precautions
- Do not use on areas with wounds, swelling, eczema, or other skin abnormalities.
- If it does not suit your skin (redness, swelling, itching, irritation, loss of color/white spots, darkening, etc.), discontinue use and consult a dermatologist. Continuing use may worsen symptoms.
- Be careful not to get it in your eyes. If it gets into your eyes, rinse immediately with water or lukewarm water. If abnormalities persist, consult an ophthalmologist.
- If it gets on clothing or other items, wash off immediately with water. It may cause discoloration or deterioration.
- For external use only. Do not ingest.
Storage Precautions
📦 Storage and Handling Precautions
- Make sure to close the cap tightly after use.
- Avoid direct sunlight, high temperatures, and low temperatures; store at room temperature.
- Keep out of reach of infants and young children.
- Do not transfer to other containers (this may cause misuse or quality changes).
- This product is not classified as dangerous goods for air transport (there are no restrictions on carrying it on board or in luggage, but please follow the regulations of each airline).













































































