

Fluid buildup in the knee
What causes it?
Why does "fluid build up in the knee"? Intense exercise like sports, injuries, and aging cause worn cartilage (①), which leads to joint inflammation. The inflammation stimulates synovial cells (②), causing excessive production of “synovial fluid (③),” the lubricant of the knee joint, resulting in fluid buildup in the knee.

*Our company survey FA (February 2025) N=85 (men and women aged 20-69 who have experienced fluid buildup in the knee within the past year)
*Voices matching our company’s planning intent are excerpted and edited for introduction

Mizunain's
Effects and Mechanism
Mizunain is a Kampo formula called "Eppikajutsubuto," made from 7 types of herbal medicines, which calms inflammation caused by fluid buildup in the knee, reduces the fluid accumulated in the knee, and improves painful and distressing knee symptoms.

Knee
Calming inflammation and reducing fluidBy
Recurring"Pain and difficulty moving"
Effective for!

Mizunain Product Information

Easy-to-take Tablet type |
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- Ingredients and Quantity
- Daily amount (12 Tablets): 2.6g of Eppikajutsubuto extract
Ephedra, Gypsum, Atractylodes, Aconite powder, Ginger, Licorice, Jujube
Contains anhydrous silica, silica Al, CMC-Ca, lactose, and magnesium stearate as additives - Indications and Effects
- For those with moderate or higher physical strength who experience coldness, swelling, thirst, sweating, and sometimes reduced urine output, the following symptoms: swelling, joint swelling and pain, muscle pain, eczema/dermatitis, bedwetting, eye itching and pain
- Dosage and Administration
- Adults (15 years and older): Take 4 Tablets per dose, 3 times a day before or between meals with water or hot water. (Do not take if under 15 years old)












































































