Works long with twice-daily dosing.
Sustained-Release Pabron.
Feature 1
Taken twice daily, morning and evening, for long-lasting effects!
Sustained-Release Pabron Tablets are designed considering the needs and conditions of cold medicine. Taken twice daily, morning and evening, the effects last long through the day and night to early morning. Non-caffeine, making it easy to take at night.
Feature 2
Effective against 11 troublesome cold symptoms!
Six active ingredients, including ibuprofen which acts on the source of pain and fever, ambroxol hydrochloride which cares for airway mucosa, and d-chlorpheniramine maleate which suppresses sneezing, runny nose, and nasal congestion, work effectively to relieve 11 troublesome cold symptoms.
Feature 3
Dissolves quickly and works long! Time-lag action tablets
Sustained-Release Pabron Tablets are the first OTC medicine to simultaneously sustain two active ingredients (ibuprofen and ambroxol hydrochloride). This is a sustained-release cold medicine taken twice a day that provides long-lasting, excellent effects.
Feature 4
Small tablets designed for easy swallowing
Our unique formulation technology achieves sustained release of active ingredients while reducing the tablet size!
● Features
◆ Jizokusei Paburon Tablets combine six active ingredients including the antipyretic analgesic ingredient ibuprofen and the airway mucosa care ingredient ambroxol hydrochloride, and are cold medicine effective for 11 distressing cold symptoms such as sore throat, cough, runny nose, and fever.
◆ The "time-difference action tablet," consisting of a fast-dissolving layer and a slow-dissolving layer, provides sustained effects with twice-daily doses in the morning and evening.
◆ These are easy-to-swallow small tablets and caffeine-free cold medicine.
【Designated Class 2 OTC Drug】
● Efficacy/Effects
Relief of various cold symptoms (sore throat, cough, phlegm, runny nose, nasal congestion, sneezing, fever, chills (chills due to fever), headache, joint pain, muscle pain)
＜Precautions related to Efficacy/Effects＞
● Dosage and Administration
Take the following amount with water or lukewarm water.
Take within 30 minutes after breakfast and dinner as much as possible.
［Age: Single dose: Number of doses］
Adults (15 years and older): 3 tablets: 2 times a day
Under 15 years old: Do not take
＜Precautions related to Dosage and Administration＞
(1) Strictly follow the prescribed dosage and administration.
(2) Do not split, crush, or grind the tablets; take them whole without chewing.
(3) How to remove tablets
Press firmly on the raised part of the PTP sheet containing the tablets with your fingertip to break the aluminum foil on the back, then take out and take the tablet.
(Swallowing it accidentally as is may cause unexpected accidents such as piercing the esophageal mucosa.)
● Ingredients/Quantity
Per 6 tablets
Ibuprofen 400 mg
d-Chlorpheniramine Maleate 3.5 mg
Dihydrocodeine Phosphate 16 mg
dl-Methylephedrine Hydrochloride 60 mg
Ambroxol Hydrochloride 45 mg
Riboflavin 8 mg
〔Additives〕
Cellulose, anhydrous silica, calcium hydrogen phosphate, hypromellose (hydroxypropyl methylcellulose), sodium starch glycolate, magnesium stearate, citric acid
＜Precautions related to Ingredients/Quantity＞
Urine may turn yellow after taking this medicine, but this is due to the vitamin B2 in this medicine and is not a cause for concern.
● Dosage Form
Tablets (oral tablets)
● Precautions for Use
■Do not do (Contraindications)
(If not followed, current symptoms may worsen or side effects/accidents may occur more easily)
1. Do not take if you fall under any of the following:
(1) Those who have had allergic reactions to this medicine or its ingredients.
(2) Those who have had asthma attacks after taking this medicine or other cold medicines or antipyretic analgesics.
(3) Children under 15 years old.
(4) Pregnant women within 12 weeks before the expected delivery date.
2. Do not use any of the following medicines while taking this medicine:
Other cold medicines, antipyretic analgesics, sedatives, antitussives and expectorants, oral medicines containing antihistamines (oral medicines for rhinitis, motion sickness medicines, allergy medicines, etc.)
3. Do not drive vehicles or operate machinery after taking this medicine
(Drowsiness or other symptoms may appear)
4. Nursing mothers should either not take this medicine or avoid breastfeeding while taking it.
5. Do not drink alcohol before or after taking this medicine.
6. Do not take for more than 5 days.
■Consult
1. Consult a doctor, pharmacist, or registered seller before taking if you fall under any of the following:
(1) Those receiving treatment from a doctor or dentist.
(2) Pregnant women or those who may be pregnant.
(3) Elderly people.
(4) Those who have had allergic reactions to medicines.
(5) Those with the following symptoms:
High fever, difficulty urinating
(6) Those diagnosed with the following:
Thyroid dysfunction, diabetes, heart disease, hypertension, liver disease, kidney disease, glaucoma, systemic lupus erythematosus, mixed connective tissue disease, respiratory dysfunction, obstructive sleep apnea syndrome, obesity
(7) Those who have had the following diseases:
Gastric or duodenal ulcer, ulcerative colitis, Crohn's disease
2. If any of the following symptoms appear after taking this medicine, they may be side effects. Stop taking immediately and consult a doctor, pharmacist, or registered seller with this leaflet.
［Affected area: Symptoms］
Skin: Rash, redness, itching, swelling, bruising
Digestive system: Nausea, vomiting, loss of appetite, stomach discomfort, stomach pain, stomatitis, heartburn, indigestion, gastrointestinal bleeding, abdominal pain, diarrhea, bloody stool, stomach/abdominal bloating
Nervous system: Dizziness, numbness
Circulatory system: Palpitations
Respiratory system: Shortness of breath
Urinary system: Difficulty urinating
Others: Blurred vision, tinnitus, swelling, nosebleed, bleeding gums, bleeding that is hard to stop, bleeding, back pain, excessive body temperature drop, fatigue
Rarely, the following serious symptoms may occur. In such cases, seek medical attention immediately.
［Name of Symptom: Symptom］
Shock (Anaphylaxis): Immediately after taking, itching of the skin, hives, hoarseness, sneezing, throat itching, difficulty breathing, palpitations, clouding of consciousness, etc. appear.
Stevens-Johnson Syndrome (skin mucous membrane eye syndrome): High fever, eye redness, eye discharge, lip erosion, sore throat, widespread rash/redness of the skin persist or rapidly worsen.
Toxic Epidermal Necrolysis: High fever, eye redness, eye discharge, lip erosion, sore throat, widespread rash/redness of the skin persist or rapidly worsen.
Liver dysfunction: Fever, itching, rash, jaundice (yellowing of skin and whites of eyes), dark urine, general fatigue, loss of appetite, etc. appear.
Kidney disorder: Fever, rash, decreased urine output, generalized swelling, general fatigue, joint pain, diarrhea, etc. appear.
Aseptic meningitis: Severe headache with neck stiffness, fever, nausea, vomiting, etc. appear. (These symptoms are often reported especially in people receiving treatment for systemic lupus erythematosus or mixed connective tissue disease.)
Interstitial pneumonia: Shortness of breath or difficulty breathing when climbing stairs or exerting slightly, dry cough, fever, etc. appear suddenly or persist.
Asthma: Wheezing or whistling sounds when breathing, difficulty breathing, etc. appear.
Aplastic anemia: Bruising, nosebleeds, bleeding gums, fever, pale skin or mucous membranes, fatigue, palpitations, shortness of breath, dizziness, hematuria, etc. appear.
Agranulocytosis: Sudden high fever, chills, sore throat, etc. appear.
Respiratory depression: Shortness of breath, difficulty breathing, etc. appear.
3. The following symptoms may appear after taking this medicine. If these symptoms persist or worsen, stop taking and consult a doctor, pharmacist, or registered seller with this leaflet:
Constipation, dry mouth, drowsiness
4. If symptoms do not improve after 3 to 4 doses, stop taking and consult a doctor, pharmacist, or registered seller with this leaflet.
(Especially if fever lasts more than 3 days or recurs)
●Precautions for Storage and Handling
(1) Store in a cool, dry place away from direct sunlight.
(2) Keep out of reach of children.
(3) Do not transfer to another container. (This may cause misuse or change the quality.)
(4) Do not take products past the expiration date. Even within the expiration date, take within 6 months after opening. (For quality maintenance)
