Heparize Plus II
Contains liver hydrolysate. For nutrition supply during daily fatigue or digestive system discomfort.
For these people and situations
Product Overview
Heparize Plus II is a Class 3 OTC Drug containing "liver hydrolysate," which is natural, high-quality liver broken down for easy digestion and absorption as its main ingredient. It activates liver metabolism and provides tonic effects. In addition to liver hydrolysate, it contains inositol to support metabolism, and vitamin B2 and vitamin E acetate ester essential for overall metabolism. This medicine supports nourishment and tonic effects for those with busy daily lives. It is designed as reddish-brown sugar-coated tablets for easy intake.
Product Features
Liver components in an easy-to-digest and absorb form
Liver hydrolysateNatural, high-quality liver hydrolyzed by adding digestive enzymes and broken down into amino acids and peptides. Contains 18 types of amino acids and nucleic acid precursors, supporting metabolism.
Enhances metabolism
InositolWorks together with liver hydrolysate to provide tonic effects. It is an ingredient that supports the maintenance of liver and digestive system functions.
Supports overall nutrition supply
Vitamin E acetate esterWorks as a fat-soluble vitamin to promote overall metabolism. The amount included has been increased compared to the previous product (New Heparize Plus).
Supports energy metabolism
Vitamin B2A vitamin essential for carbohydrate, fat, and protein metabolism. Supports overall metabolism and helps with nutrition supply.
🫀 What is liver hydrolysate?
This is natural, high-quality liver hydrolyzed by adding digestive enzymes and broken down into amino acids and peptides. Since it is pre-digested in place of the human digestive system, it is in a form that is easy to digest and absorb.
Feature: Easy-to-digest and absorb form
Natural liver is hydrolyzed by adding digestive enzymes. By converting into amino acids and peptides, absorption into the body becomes smoother.
Action: 18 types of amino acids + nucleic acid precursors
Contains 18 types of amino acids including essential amino acids, and "nucleic acid precursors" necessary for cell regeneration, supporting metabolism.
😴 That fatigue might be caused by your liver or digestive system
"Even after resting, fatigue doesn't go away" or "You still feel sluggish when you wake up in the morning" — this might not just be muscle fatigue but could be caused by declining liver and digestive system function. When the liver and digestive system are tired, energy production decreases, leading to overall stamina depletion.
Liver Fatigue
The liver plays two major roles: "metabolism" and "detoxification." When its function declines, it becomes harder to convert nutrients from food into energy, and the breakdown of harmful substances slows down, leading to fatigue and sluggishness in the body.
Fatigue of the digestive system
When the digestive and absorptive capacity of the stomach and intestines declines, food cannot be efficiently converted into nutrients. Continued nutritional deficiency reduces nutrients reaching the liver, leading to overall energy shortage and fatigue.
- Low protein and nutritional deficiency: Energy sources for the liver are insufficient
- Weak stomach and indigestion: Reduced nutrient absorption leads to a shortage of energy sources for the liver
- High protein and high fat diet: The liver is burdened by processing excessive nutrients
- Lack of exercise: Blood stagnates due to decreased detoxification and metabolism
- Constipation: Increased detoxification burden from toxins (gas) produced in the intestines
- Lack of sleep: The liver cannot rest and continues working, making it prone to fatigue
Active ingredients
| Ingredient name | Per daily dose (6 Tablets) | Classification |
|---|---|---|
| Liver hydrolysate | 600mg | Tonic and metabolism |
| Inositol | 100mg | Metabolism support |
| Vitamin B2 (Riboflavin) | 12mg | Vitamin |
| Vitamin E acetate ester | 10mg | Vitamin |
Efficacy and Effects
Usage and Dosage
| Age | Amount per dose | Number of times per day |
|---|---|---|
| Adults (15 years and older) | 3 Tablets | 2 times |
| Under 15 years old | Do not take if | |
🌱 Brand Story
Zeria Pharmaceutical launched "Heparize Tablet" as a liver disorder treatment drug. Marked a new chapter in Japan's tonic market.
Launched "New Heparize Tablet" containing tonic and liver hydrolysate. Full-scale expansion as a Class 3 OTC Drug.
Launched "Heparize Oral Liquid" and "Heparize Drink." Expanded the lineup of easy-to-drink liquid medicines.
Heparize Plus II launched. Newly formulated with inositol and increased amount of vitamin E acetate ester. Evolved to a more enriched ingredient design.
The Heparize brand, with over 50 years of history, is based on the concept of "fatigue from the liver and digestive system." It continues to support the nutrition and tonic needs of busy modern people.
- If a rash appears on the skin after taking, it may be a side effect, so stop taking immediately and consult a doctor, pharmacist, or registered seller.
- If symptoms do not improve after taking for a while, stop taking it and consult a doctor, pharmacist, or registered seller.
- Follow the prescribed usage and dosage.
- This product is a medicine. If you have any questions, please consult a pharmacist or registered seller.
- Store away from direct sunlight, high temperature, and humidity.
- Keep out of reach of children.
- Do not transfer to other containers (this may cause misuse or change the quality).















































































