{"product_id":"heparize-plus2","title":"Heparize Plus II","description":"\u003cstyle\u003e\n.pd-wrap {\n  --acc:       #8b1a1a;\n  --acc-dark:  #5a0f0f;\n  --acc-light: #f8eaea;\n  --acc-mid:   #c06060;\n}\n\u003c\/style\u003e\n\n\u003cdiv class=\"pd-wrap\"\u003e\n\n\u003cdiv class=\"pd-hero\"\u003e\n  \u003cdiv class=\"pd-hero__badges\"\u003e\n    \u003cspan class=\"pd-hero__badge\"\u003eClass 3 OTC Drug\u003c\/span\u003e\n    \u003cspan class=\"pd-hero__badge\"\u003eSugar-coated Tablet\u003c\/span\u003e\n    \u003cspan class=\"pd-hero__badge\"\u003eZeria Pharmaceutical\u003c\/span\u003e\n  \u003c\/div\u003e\n  \u003ch1 class=\"pd-hero__title\"\u003eHeparize Plus II\u003c\/h1\u003e\n  \u003cp class=\"pd-hero__tagline\"\u003eContains liver hydrolysate. For nutrition supply during daily fatigue or digestive system discomfort.\u003c\/p\u003e\n  \u003cdiv class=\"pd-hero__pills\"\u003e\n    \u003cspan class=\"pd-hero__pill\"\u003e✦ Contains 600mg liver hydrolysate\u003c\/span\u003e\n    \u003cspan class=\"pd-hero__pill\"\u003e✦ Contains inositol\u003c\/span\u003e\n    \u003cspan class=\"pd-hero__pill\"\u003e✦ Contains vitamin B2 and E\u003c\/span\u003e\n    \u003cspan class=\"pd-hero__pill\"\u003e✦ OK before or after meals\u003c\/span\u003e\n  \u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pd-for-whom\"\u003e\n  \u003ch2 class=\"pd-section__title\"\u003eFor these people and situations\u003c\/h2\u003e\n  \u003cdiv class=\"pd-for-whom__grid\"\u003e\n    \u003cdiv class=\"pd-for-whom__item\"\u003e\n      \u003cdiv class=\"pd-for-whom__icon\"\u003e😓\u003c\/div\u003e\n      \u003cdiv class=\"pd-for-whom__text\"\u003e\n        \u003cstrong\u003eFor those who easily feel tired\u003c\/strong\u003e\n        \u003cspan\u003eFor nutrition supply when socializing or overtime work continues and you feel bodily fatigue.\u003c\/span\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"pd-for-whom__item\"\u003e\n      \u003cdiv class=\"pd-for-whom__icon\"\u003e🍽️\u003c\/div\u003e\n      \u003cdiv class=\"pd-for-whom__text\"\u003e\n        \u003cstrong\u003eFor those concerned about digestive system condition\u003c\/strong\u003e\n        \u003cspan\u003eFor nutrition supply when you have no appetite or feel your digestive system is not in good condition.\u003c\/span\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"pd-for-whom__item\"\u003e\n      \u003cdiv class=\"pd-for-whom__icon\"\u003e🏥\u003c\/div\u003e\n      \u003cdiv class=\"pd-for-whom__text\"\u003e\n        \u003cstrong\u003eFor those during and after illness or in recovery\u003c\/strong\u003e\n        \u003cspan\u003eFor nutrition supply when physical strength is reduced due to febrile wasting diseases or during and after illness.\u003c\/span\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"pd-for-whom__item\"\u003e\n      \u003cdiv class=\"pd-for-whom__icon\"\u003e🌸\u003c\/div\u003e\n      \u003cdiv class=\"pd-for-whom__text\"\u003e\n        \u003cstrong\u003eFor nutrition supply during pregnancy and breastfeeding\u003c\/strong\u003e\n        \u003cspan\u003eSupports nutrition supply during periods when the body needs nourishment, such as pregnancy and breastfeeding.\u003c\/span\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pd-section\"\u003e\n  \u003ch2 class=\"pd-section__title\"\u003eProduct Overview\u003c\/h2\u003e\n  \u003cp\u003eHeparize Plus II is a Class 3 OTC Drug containing \"liver hydrolysate,\" which is natural, high-quality liver broken down for easy digestion and absorption as its main ingredient. It activates liver metabolism and provides tonic effects. In addition to liver hydrolysate, it contains inositol to support metabolism, and vitamin B2 and vitamin E acetate ester essential for overall metabolism. This medicine supports nourishment and tonic effects for those with busy daily lives. It is designed as reddish-brown sugar-coated tablets for easy intake.\u003c\/p\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pd-section\"\u003e\n  \u003ch2 class=\"pd-section__title\"\u003eProduct Features\u003c\/h2\u003e\n  \u003cdiv class=\"pd-grid pd-grid--2col\"\u003e\n    \u003cdiv class=\"pd-card pd-card--feature\"\u003e\n      \u003cspan class=\"pd-card__num\"\u003e01\u003c\/span\u003e\n      \u003ch3 class=\"pd-card__title\"\u003eLiver components in an easy-to-digest and absorb form\u003c\/h3\u003e\n      \u003cspan class=\"pd-card__pill\"\u003eLiver hydrolysate\u003c\/span\u003e\n      \u003cp class=\"pd-card__text\"\u003eNatural, high-quality liver hydrolyzed by adding digestive enzymes and broken down into amino acids and peptides. Contains 18 types of amino acids and nucleic acid precursors, supporting metabolism.\u003c\/p\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"pd-card pd-card--feature\"\u003e\n      \u003cspan class=\"pd-card__num\"\u003e02\u003c\/span\u003e\n      \u003ch3 class=\"pd-card__title\"\u003eEnhances metabolism\u003c\/h3\u003e\n      \u003cspan class=\"pd-card__pill\"\u003eInositol\u003c\/span\u003e\n      \u003cp class=\"pd-card__text\"\u003eWorks together with liver hydrolysate to provide tonic effects. It is an ingredient that supports the maintenance of liver and digestive system functions.\u003c\/p\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"pd-card pd-card--feature\"\u003e\n      \u003cspan class=\"pd-card__num\"\u003e03\u003c\/span\u003e\n      \u003ch3 class=\"pd-card__title\"\u003eSupports overall nutrition supply\u003c\/h3\u003e\n      \u003cspan class=\"pd-card__pill\"\u003eVitamin E acetate ester\u003c\/span\u003e\n      \u003cp class=\"pd-card__text\"\u003eWorks as a fat-soluble vitamin to promote overall metabolism. The amount included has been increased compared to the previous product (New Heparize Plus).\u003c\/p\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"pd-card pd-card--feature\"\u003e\n      \u003cspan class=\"pd-card__num\"\u003e04\u003c\/span\u003e\n      \u003ch3 class=\"pd-card__title\"\u003eSupports energy metabolism\u003c\/h3\u003e\n      \u003cspan class=\"pd-card__pill\"\u003eVitamin B2\u003c\/span\u003e\n      \u003cp class=\"pd-card__text\"\u003eA vitamin essential for carbohydrate, fat, and protein metabolism. Supports overall metabolism and helps with nutrition supply.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pd-section\"\u003e\n  \u003ch2 class=\"pd-section__title\"\u003e🫀 What is liver hydrolysate?\u003c\/h2\u003e\n  \u003cp\u003eThis is natural, high-quality liver hydrolyzed by adding digestive enzymes and broken down into amino acids and peptides. Since it is pre-digested in place of the human digestive system, it is in a form that is easy to digest and absorb.\u003c\/p\u003e\n  \u003cdiv class=\"pd-grid pd-grid--2col\"\u003e\n    \u003cdiv class=\"pd-card pd-card--feature\"\u003e\n      \u003cspan class=\"pd-card__num\"\u003e🌿\u003c\/span\u003e\n      \u003ch3 class=\"pd-card__title\"\u003eFeature: Easy-to-digest and absorb form\u003c\/h3\u003e\n      \u003cp class=\"pd-card__text\"\u003eNatural liver is hydrolyzed by adding digestive enzymes. By converting into amino acids and peptides, absorption into the body becomes smoother.\u003c\/p\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"pd-card pd-card--feature\"\u003e\n      \u003cspan class=\"pd-card__num\"\u003e⚡\u003c\/span\u003e\n      \u003ch3 class=\"pd-card__title\"\u003eAction: 18 types of amino acids + nucleic acid precursors\u003c\/h3\u003e\n      \u003cp class=\"pd-card__text\"\u003eContains 18 types of amino acids including essential amino acids, and \"nucleic acid precursors\" necessary for cell regeneration, supporting metabolism.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/div\u003e\n\u003c\/div\u003e\n  \u003cdiv class=\"pd-section\"\u003e\n  \u003ch2 class=\"pd-section__title\"\u003e😴 That fatigue might be caused by your liver or digestive system\u003c\/h2\u003e\n  \u003cp\u003e\"Even after resting, fatigue doesn't go away\" or \"You still feel sluggish when you wake up in the morning\" — this might not just be muscle fatigue but could be caused by \u003cstrong\u003edeclining liver and digestive system function\u003c\/strong\u003e. When the liver and digestive system are tired, energy production decreases, leading to overall stamina depletion.\u003c\/p\u003e\n\n  \u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0527\/4068\/5983\/files\/heparize_role1.jpg?v=1778717653\" alt=\"Diagram of the Relationship Between Liver, Digestive System, and Fatigue\" style=\"width:100%; border-radius:8px; margin:16px 0;\"\u003e\n\n  \u003cdiv class=\"pd-grid pd-grid--2col\"\u003e\n    \u003cdiv class=\"pd-card pd-card--feature\"\u003e\n      \u003cspan class=\"pd-card__num\"\u003e🫀\u003c\/span\u003e\n      \u003ch3 class=\"pd-card__title\"\u003eLiver Fatigue\u003c\/h3\u003e\n      \u003cp class=\"pd-card__text\"\u003eThe liver plays two major roles: \"metabolism\" and \"detoxification.\" When its function declines, it becomes harder to convert nutrients from food into energy, and the breakdown of harmful substances slows down, leading to fatigue and sluggishness in the body.\u003c\/p\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"pd-card pd-card--feature\"\u003e\n      \u003cspan class=\"pd-card__num\"\u003e🫃\u003c\/span\u003e\n      \u003ch3 class=\"pd-card__title\"\u003eFatigue of the digestive system\u003c\/h3\u003e\n      \u003cp class=\"pd-card__text\"\u003eWhen the digestive and absorptive capacity of the stomach and intestines declines, food cannot be efficiently converted into nutrients. Continued nutritional deficiency reduces nutrients reaching the liver, leading to overall energy shortage and fatigue.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/div\u003e\n\n  \u003cdiv class=\"pd-note pd-note--warning\" style=\"margin-top:16px;\"\u003e\n    \u003cdiv class=\"pd-note__title\"\u003e⚡ Main factors that burden internal organs in daily life\u003c\/div\u003e\n    \u003cul class=\"pd-note__list\"\u003e\n      \u003cli\u003e\n\u003cstrong\u003eLow protein and nutritional deficiency\u003c\/strong\u003e: Energy sources for the liver are insufficient\u003c\/li\u003e\n      \u003cli\u003e\n\u003cstrong\u003eWeak stomach and indigestion\u003c\/strong\u003e: Reduced nutrient absorption leads to a shortage of energy sources for the liver\u003c\/li\u003e\n      \u003cli\u003e\n\u003cstrong\u003eHigh protein and high fat diet\u003c\/strong\u003e: The liver is burdened by processing excessive nutrients\u003c\/li\u003e\n      \u003cli\u003e\n\u003cstrong\u003eLack of exercise\u003c\/strong\u003e: Blood stagnates due to decreased detoxification and metabolism\u003c\/li\u003e\n      \u003cli\u003e\n\u003cstrong\u003eConstipation\u003c\/strong\u003e: Increased detoxification burden from toxins (gas) produced in the intestines\u003c\/li\u003e\n      \u003cli\u003e\n\u003cstrong\u003eLack of sleep\u003c\/strong\u003e: The liver cannot rest and continues working, making it prone to fatigue\u003c\/li\u003e\n    \u003c\/ul\u003e\n  \u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pd-section\"\u003e\n  \u003ch2 class=\"pd-section__title\"\u003eActive ingredients\u003c\/h2\u003e\n  \u003cdiv class=\"pd-table-wrap\"\u003e\n    \u003ctable class=\"pd-table pd-table--scroll pd-table--ingredients\"\u003e\n      \u003cthead\u003e\n        \u003ctr\u003e\n\u003cth\u003eIngredient name\u003c\/th\u003e\n\u003cth\u003ePer daily dose (6 Tablets)\u003c\/th\u003e\n\u003cth\u003eClassification\u003c\/th\u003e\n\u003c\/tr\u003e\n      \u003c\/thead\u003e\n      \u003ctbody\u003e\n        \u003ctr\u003e\n          \u003ctd\u003eLiver hydrolysate\u003c\/td\u003e\n          \u003ctd\u003e600mg\u003c\/td\u003e\n          \u003ctd\u003e\u003cspan class=\"pd-pill pd-pill--category\"\u003eTonic and metabolism\u003c\/span\u003e\u003c\/td\u003e\n        \u003c\/tr\u003e\n        \u003ctr\u003e\n          \u003ctd\u003eInositol\u003c\/td\u003e\n          \u003ctd\u003e100mg\u003c\/td\u003e\n          \u003ctd\u003e\u003cspan class=\"pd-pill pd-pill--category\"\u003eMetabolism support\u003c\/span\u003e\u003c\/td\u003e\n        \u003c\/tr\u003e\n        \u003ctr\u003e\n          \u003ctd\u003eVitamin B2 (Riboflavin)\u003c\/td\u003e\n          \u003ctd\u003e12mg\u003c\/td\u003e\n          \u003ctd\u003e\u003cspan class=\"pd-pill pd-pill--category\"\u003eVitamin\u003c\/span\u003e\u003c\/td\u003e\n        \u003c\/tr\u003e\n        \u003ctr\u003e\n          \u003ctd\u003eVitamin E acetate ester\u003c\/td\u003e\n          \u003ctd\u003e10mg\u003c\/td\u003e\n          \u003ctd\u003e\u003cspan class=\"pd-pill pd-pill--category\"\u003eVitamin\u003c\/span\u003e\u003c\/td\u003e\n        \u003c\/tr\u003e\n      \u003c\/tbody\u003e\n    \u003c\/table\u003e\n  \u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pd-section\"\u003e\n  \u003ch2 class=\"pd-section__title\"\u003eEfficacy and Effects\u003c\/h2\u003e\n  \u003cdiv class=\"pd-tags\"\u003e\n    \u003cspan class=\"pd-tag pd-tag--efficacy\"\u003eTonic\u003c\/span\u003e\n    \u003cspan class=\"pd-tag pd-tag--efficacy\"\u003eNutritional supplementation for digestive disorders and nutritional deficiencies\u003c\/span\u003e\n    \u003cspan class=\"pd-tag pd-tag--efficacy\"\u003eNutritional supplementation during illness and recovery\u003c\/span\u003e\n    \u003cspan class=\"pd-tag pd-tag--efficacy\"\u003eNutritional supplementation during physical fatigue\u003c\/span\u003e\n    \u003cspan class=\"pd-tag pd-tag--efficacy\"\u003eNutritional supplementation during febrile wasting diseases\u003c\/span\u003e\n    \u003cspan class=\"pd-tag pd-tag--efficacy\"\u003eNutritional supplementation during pregnancy and lactation\u003c\/span\u003e\n    \u003cspan class=\"pd-tag pd-tag--efficacy\"\u003eWeak constitution\u003c\/span\u003e\n  \u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pd-section\"\u003e\n  \u003ch2 class=\"pd-section__title\"\u003eUsage and Dosage\u003c\/h2\u003e\n  \u003cdiv class=\"pd-table-wrap\"\u003e\n    \u003ctable class=\"pd-table pd-table--dosage\"\u003e\n      \u003cthead\u003e\n        \u003ctr\u003e\n\u003cth\u003eAge\u003c\/th\u003e\n\u003cth\u003eAmount per dose\u003c\/th\u003e\n\u003cth\u003eNumber of times per day\u003c\/th\u003e\n\u003c\/tr\u003e\n      \u003c\/thead\u003e\n      \u003ctbody\u003e\n        \u003ctr\u003e\n          \u003ctd\u003eAdults (15 years and older)\u003c\/td\u003e\n          \u003ctd\u003e3 Tablets\u003c\/td\u003e\n          \u003ctd\u003e2 times\u003c\/td\u003e\n        \u003c\/tr\u003e\n        \u003ctr\u003e\n          \u003ctd\u003eUnder 15 years old\u003c\/td\u003e\n          \u003ctd colspan=\"2\"\u003eDo not take if\u003c\/td\u003e\n        \u003c\/tr\u003e\n      \u003c\/tbody\u003e\n    \u003c\/table\u003e\n  \u003c\/div\u003e\n  \u003cdiv class=\"pd-dosage-note\"\u003eCan be taken before or after meals. Follow the prescribed usage and dosage.\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pd-section\"\u003e\n  \u003ch2 class=\"pd-section__title\"\u003e🌱 Brand Story\u003c\/h2\u003e\n  \u003cdiv class=\"pd-timeline\"\u003e\n    \u003cdiv class=\"pd-timeline__item\"\u003e\n      \u003cdiv class=\"pd-timeline__year\"\u003e1968\u003c\/div\u003e\n      \u003cp class=\"pd-timeline__text\"\u003eZeria Pharmaceutical launched \"Heparize Tablet\" as a liver disorder treatment drug. Marked a new chapter in Japan's tonic market.\u003c\/p\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"pd-timeline__item\"\u003e\n      \u003cdiv class=\"pd-timeline__year\"\u003e1979\u003c\/div\u003e\n      \u003cp class=\"pd-timeline__text\"\u003eLaunched \"New Heparize Tablet\" containing tonic and liver hydrolysate. Full-scale expansion as a Class 3 OTC Drug.\u003c\/p\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"pd-timeline__item\"\u003e\n      \u003cdiv class=\"pd-timeline__year\"\u003e1994\u003c\/div\u003e\n      \u003cp class=\"pd-timeline__text\"\u003eLaunched \"Heparize Oral Liquid\" and \"Heparize Drink.\" Expanded the lineup of easy-to-drink liquid medicines.\u003c\/p\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"pd-timeline__item\"\u003e\n      \u003cdiv class=\"pd-timeline__year\"\u003e2015\u003c\/div\u003e\n      \u003cp class=\"pd-timeline__text\"\u003eHeparize Plus II launched. Newly formulated with inositol and increased amount of vitamin E acetate ester. Evolved to a more enriched ingredient design.\u003c\/p\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"pd-timeline__item\"\u003e\n      \u003cdiv class=\"pd-timeline__year\"\u003eCurrent\u003c\/div\u003e\n      \u003cp class=\"pd-timeline__text\"\u003eThe Heparize brand, with over 50 years of history, is based on the concept of \"fatigue from the liver and digestive system.\" It continues to support the nutrition and tonic needs of busy modern people.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pd-note pd-note--warning\"\u003e\n  \u003cdiv class=\"pd-note__title\"\u003e⚠️ Usage Precautions\u003c\/div\u003e\n  \u003cul class=\"pd-note__list\"\u003e\n    \u003cli\u003eIf a rash appears on the skin after taking, it may be a side effect, so stop taking immediately and consult a doctor, pharmacist, or registered seller.\u003c\/li\u003e\n    \u003cli\u003eIf symptoms do not improve after taking for a while, stop taking it and consult a doctor, pharmacist, or registered seller.\u003c\/li\u003e\n    \u003cli\u003eFollow the prescribed usage and dosage.\u003c\/li\u003e\n    \u003cli\u003eThis product is a medicine. If you have any questions, please consult a pharmacist or registered seller.\u003c\/li\u003e\n  \u003c\/ul\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pd-note pd-note--storage\"\u003e\n  \u003cdiv class=\"pd-note__title\"\u003e📦 Storage Precautions\u003c\/div\u003e\n  \u003cul class=\"pd-note__list\"\u003e\n    \u003cli\u003eStore away from direct sunlight, high temperature, and humidity.\u003c\/li\u003e\n    \u003cli\u003eKeep out of reach of children.\u003c\/li\u003e\n    \u003cli\u003eDo not transfer to other containers (this may cause misuse or change the quality).\u003c\/li\u003e\n  \u003c\/ul\u003e\n\u003c\/div\u003e\n\n\u003c\/div\u003e\u003c!-- \/.pd-wrap --\u003e","brand":"ZERIA","offers":[{"title":"6 Tablet","offer_id":52091804713276,"sku":"4987103049098","price":330.0,"currency_code":"JPY","in_stock":true},{"title":"60 Tablet","offer_id":52091804746044,"sku":"4987103049104","price":1980.0,"currency_code":"JPY","in_stock":true},{"title":"180 Tablet","offer_id":52091804778812,"sku":"4987103049111","price":4950.0,"currency_code":"JPY","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/9803\/0652\/files\/4987103049098.jpg?v=1756707614","url":"https:\/\/mamigo.jp\/en-ph\/products\/heparize-plus2","provider":"MamiGo","version":"1.0","type":"link"}