● Features
Excedrin has products with different active ingredients. The antipyretic analgesic ingredients of this product are aspirin (acetylsalicylic acid) and acetaminophen. When consulting a doctor, dentist, pharmacist, or registered seller, please inform them of aspirin (acetylsalicylic acid) and acetaminophen.
For severe pain such as headache, stiff shoulders, and lower back pain!
(1) Three ingredients quickly exert excellent effects
　● Aspirin (acetylsalicylic acid)　● Acetaminophen　● Anhydrous caffeine
(2) Does not contain ingredients that cause drowsiness
(3) Non-pyrazolone type

【Designated Class 2 OTC Drug】

● Efficacy/Effects
Relief of pain such as headache, stiff shoulders, lower back pain, menstrual pain (period pain), toothache, pain after tooth extraction, muscle pain, bruises, fracture pain, sprain pain, sore throat, ear pain, joint pain, neuralgia, trauma pain, and antipyretic effect during chills and fever

＜Precautions related to Efficacy/Effects＞


● Dosage and Administration
Take preferably avoiding an empty stomach. Keep an interval of 6 hours or more between doses.
Take the following amount with water or lukewarm water.
［Age: Dose per time: Number of doses per day］
Adults (15 years and older): 2 tablets: up to 2 times
Under 15 years: Do not take


＜Precautions related to Dosage and Administration＞
(1) Strictly follow the dosage and administration instructions.
(2) How to take out the tablets: Press strongly on the convex part of the PTP sheet containing the tablets with your fingertip to break the aluminum foil on the back, take out the tablet and swallow it (swallowing it accidentally as is may cause unexpected accidents such as piercing the esophageal mucosa).

● Ingredients/Quantity
Per 2 tablets
Aspirin 500mg
Acetaminophen 300mg
Anhydrous caffeine 120mg

〔Additives〕
Corn starch, carmellose (CMC), cellulose, hydroxypropyl cellulose, magnesium stearate

＜Precautions related to Ingredients/Quantity＞
Pyrazolone-type ingredients are not included.

● Dosage Form
Tablets (oral tablets)

● Precautions for Use
■Do not do (Contraindications)
(If not followed, current symptoms may worsen or side effects/accidents may occur more easily)
1. Do not take if you fall under the following:
　(1) Have had allergic reactions to this product or its ingredients.
　(2) Have had asthma caused by this product or other antipyretic analgesics or cold medicines.
　(3) Children under 15 years old.
　(4) Pregnant women within 12 weeks before the expected delivery date.
2. Do not take any of the following medicines while taking this product:
　Other antipyretic analgesics, cold medicines, sedatives
3. Do not drink alcohol before or after taking this product.
4. Do not take continuously for a long time.
■Consult
1. Consult a doctor, dentist, pharmacist, or registered seller before taking if you fall under the following:
　(1) Receiving treatment from a doctor or dentist.
　(2) Pregnant or suspected to be pregnant.
　(3) Breastfeeding.
　(4) Elderly.
　(5) Have had allergic reactions to medicines.
　(6) Have been diagnosed with the following:
　　Heart disease, kidney disease, liver disease, stomach/duodenal ulcer
2. If the following symptoms appear after taking, they may be side effects, so stop taking immediately and consult a doctor, pharmacist, or registered seller with this document.
［Affected area: Symptoms］
Skin: Rash, redness, itching, bruising
Digestive system: Nausea, vomiting, loss of appetite, heartburn, stomach heaviness, gastrointestinal bleeding, abdominal pain, diarrhea, bloody stool
Nervous system: Dizziness
Others: Nosebleed, bleeding gums, bleeding that is hard to stop, bleeding, fever, sore throat, back pain, excessive lowering of body temperature
　Rarely, the following serious symptoms may occur. In such cases, seek medical attention immediately.
［Name of Symptom: Symptom］
Shock (Anaphylaxis): Immediately after taking, itching of the skin, hives, hoarseness, sneezing, itching of the throat, difficulty breathing, palpitations, clouding of consciousness, etc. appear.
Stevens-Johnson syndrome (skin mucous membrane eye syndrome): High fever, eye redness, eye discharge, lip erosion, sore throat, widespread rash and redness of the skin, small bumps (small pustules) on the reddened skin, general malaise, loss of appetite, etc. persist or rapidly worsen.
Toxic epidermal necrolysis: High fever, eye redness, eye discharge, lip erosion, sore throat, widespread rash and redness of the skin, small bumps (small pustules) on the reddened skin, general malaise, loss of appetite, etc. persist or rapidly worsen.
Acute generalized exanthematous pustulosis: High fever, eye redness, eye discharge, lip erosion, sore throat, widespread rash and redness of the skin, small bumps (small pustules) on the reddened skin, general malaise, loss of appetite, etc. persist or rapidly worsen.
Drug hypersensitivity syndrome: Widespread redness of the skin, systemic rash, fever, fatigue, swelling of lymph nodes (neck, armpits, groin, etc.) appear.
Liver dysfunction: Fever, itching, rash, jaundice (yellowing of skin and whites of eyes), dark urine, general fatigue, loss of appetite, etc. appear.
Kidney disorder: Fever, rash, decreased urine output, general swelling, general fatigue, joint pain, diarrhea, etc. appear.
Interstitial pneumonia: Shortness of breath or difficulty breathing when climbing stairs or exerting slightly, dry cough, fever, etc. appear suddenly or persist.
Asthma: Wheezing or whistling sounds when breathing, difficulty breathing, etc. appear.
Aplastic anemia: Bruising, nosebleeds, bleeding gums, fever, pale skin and mucous membranes, fatigue, palpitations, shortness of breath, dizziness, hematuria, etc. appear.
3. If symptoms do not improve after 5 to 6 doses, stop taking and consult a doctor, dentist, pharmacist, or registered seller with this document.

●Precautions for Storage and Handling
(1) Store in a cool, dry place away from direct sunlight.
(2) Keep out of reach of children.
(3) Do not transfer to other containers (may cause misuse or quality changes).
(4) Do not use products past the expiration date.
(5) To prevent deterioration, do not damage the aluminum foil on the back of tablets that you do not take.