Because Hirumairudo is a pharmaceutical product
Contains 0.3% heparinoid substance
Dry skin treatment medicine
Hirumairudo

Oil-in-water cream that spreads well and can be applied both locally and over wide areas

What is the active ingredient “heparinoid substance”?
Heparinoid substances are moisturizing ingredients used for many years as treatment for dry skin. They are components similar to “heparin,” a type of sugar produced in the human liver, characterized by high hydrophilicity and water retention. They have three effects: “moisturizing,” “promoting blood circulation,” and “anti-inflammatory,” and can be used on the whole body from children to the elderly. They penetrate into the stratum corneum inside the skin, exert moisturizing effects, and effectively improve dryness, inflammation, and rough skin.
Mechanism of penetrating inside the skin and retaining moisture
Heparinoid substances have the function of attracting and retaining moisture. Unlike petrolatum, which covers the skin surface to prevent moisture evaporation, heparinoid substances penetrate into the stratum corneum inside the skin and act on skin cells there.

The stratum corneum originally functions as a “barrier” that retains moisture inside the skin and protects the skin from external stimuli, but it is easily damaged or peeled off due to causes like ultraviolet rays and dryness, resulting in loss of skin moisture. Therefore, by using heparinoid substances, it improves the moisture retention function of the stratum corneum and promotes the restoration of normal barrier function. This allows moisture to be retained inside the skin.
Recommended usage method for Hirumairudo
| Use on clean bare skin |
After bathing or washing your face, apply an appropriate amount to clean bare skin and rub it directly onto the affected area, or spread it on gauze and apply it like a patch. Use cream for localized areas such as around the mouth, cheeks, or fingers. For wide areas like elbows, knees, thighs, or back, lotion is recommended. |
| When you feel symptoms caused by dryness |
When your hands are rough, doing dishes is tough. If you feel dryness or stinging even a little, use it early before the symptoms worsen. The recommended frequency is once to several times a day. |
● Features
■ Moisturizing cream type
Contains heparin-like substances
For treatment of dry skin on face, hands, and feet
・Easy-to-use one-touch cap adopted
・Steroid-free
・Colorant-free
【Class 2 OTC Drug】
● Efficacy/Effects
Roughness of fingers, keratosis of elbows, knees, heels, and ankles, cracks and chapping of hands and feet, xeroderma, dry skin in children, chilblains (excluding erosion), skin nodules and tightness after wounds and burns (excluding face), swelling after bruises and sprains, muscle pain, joint pain
<Precautions related to Efficacy/Effects>
● Dosage and Administration
Apply an appropriate amount to the affected area 1 to several times a day by rubbing it in or spreading it on gauze and applying.
<Precautions related to Dosage and Administration>
(1) Strictly follow the dosage and administration instructions.
(2) When used for children, use under the guidance and supervision of a guardian.
(3) Be careful not to get it in the eyes. If it gets into the eyes, immediately rinse with water or lukewarm water. If symptoms are severe, consult an ophthalmologist.
(4) For external use only.
● Ingredients/Quantity
Per 100g
Heparin-like substance 0.3g
〔Additives〕
Bleached beeswax, paraffin, microcrystalline wax, white petrolatum, edetate disodium hydrate, dibutylhydroxytoluene (BHT), glycerin, light liquid paraffin, squalane, glycerin fatty acid ester, polyoxyethylene cetyl ether, propylparaben, methylparaben
<Precautions related to Ingredients/Quantity>
● Dosage Form
Cream (external - topical agent)
● Precautions for Use
■Do not do (Contraindications)
(If not followed, current symptoms may worsen or side effects may occur more easily)
1. Do not use if you are:
(1) A person with hemorrhagic blood disorders (hemophilia, thrombocytopenia, purpura, etc.).
(2) A person expected to have serious consequences even with slight bleeding. (May have blood coagulation inhibitory effects and promote bleeding.)
2. Do not use on the following areas:
Eyes and surrounding areas, mucous membranes (oral cavity, nasal cavity, vagina, etc.).
■Consult
1. Consult a doctor, pharmacist, or registered seller before use if you:
(1) Are receiving medical treatment.
(2) Have had allergic reactions to medicines.
(3) Have severe moistening or erosion.
2. If the following symptoms appear after use, they may be side effects; stop use immediately and consult a doctor, pharmacist, or registered seller with this outer box.
[Affected area: Symptoms]
Skin: rash, redness, itching, swelling, purpura
3. If symptoms do not improve after 5 to 6 days of use, stop use and consult a doctor, pharmacist, or registered seller with this outer box.
●Precautions for Storage and Handling
(1) Store tightly closed in a cool, dry place away from direct sunlight.
(2) Keep out of reach of children.
(3) Do not transfer to another container. (This may cause misuse or change the quality.)
(4) Do not use products past the expiration date.