Designated Class 2 OTC Drug Plant-based laxative 🍫 Chocolate flavor Safe for first-time laxative users Made in Japan
Shin With One
Zeria Pharmaceutical Co., Ltd. / Plant-based laxative (granule Stick)
Containing three plant-derived ingredients (dietary fiber + two herbal medicines).
Gentle on the stomach yet abundant — a plant-based formula that promotes natural-like bowel movements,
Recommended even for first-time users of laxatives.
Gentle on the stomach yet abundant — a plant-based formula that promotes natural-like bowel movements,
Recommended even for first-time users of laxatives.
Chocolate-flavored smooth granules
Easy-to-carry Stick packaging
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Triple power of three plant-derived ingredients: "swelling and pushing out"
Shin With One contains three plant-derived ingredients: "swelling dietary fiber," "Sennoside, an herbal medicine that pushes out the large intestine," and "dried extract of Designated Class 2 OTC Drug Cascara Sagrada that supports intestinal function." It is gentle on the stomach and promotes abundant bowel movements.
💧 Swelling dietary fiber
Plantago Ovata Seed Husk Powder
Seed husk of Indian Plantain. Absorbs water and swells in the intestines, increasing stool bulk and promoting peristalsis. Also helps adsorb and eliminate intestinal toxins.⚡ Herbal medicine that pushes out stool
Sennoside
Herbal medicine derived from Senna. Does not act on the small intestine but selectively stimulates only the large intestine, promoting peristalsis. Activates weakened intestines to push stool out.🌱 Supports intestinal movement
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Cascara sagrada dry extract
Derived from the bark of Rhamnaceae plants native to North America. Supports the action of dietary fiber and Sennoside, regulating intestinal function.
(Image) Dietary fiber swells in the intestines, increasing stool bulk and supporting elimination
🍫 Chocolate-flavored smooth granules with adjustable dosage
Each granule swells in the intestines to increase stool bulk and support natural-like bowel movements. The smooth granule type allows dosage adjustment according to your bowel condition, and the Stick packaging makes it easy to take even when out. Chocolate flavor makes it easy to take, and it is safe for first-time laxative users to continue.
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Five features of Shin With One
01
Triple blend of three plant-derived ingredients
Achieves natural-like bowel movements with three ingredients: Plantago Ovata Seed Husk Powder (dietary fiber), Sennoside, and dried extract of Designated Class 2 OTC Drug Cascara Sagrada.
02
Gentle formula that is less likely to cause stomach pain
A plant-based formula with the concept of "natural-like bowel movements." It does not strongly stimulate the stomach and is less likely to cause dependency.
03
Safe for first-time laxative users
Based on gently acting plant-based ingredients, designed to be easy to use even for first-time users of laxatives.
04
Easy to take with chocolate flavor
Smooth granules with a chocolate flavor that are easy to continue daily. Packaged in Sticks for easy carrying and convenient intake even when out.
05
Suitable from age 3 with adjustable dosage
Suitable for ages 3 and up with age-specific dosages. Granule type adjustable in 1/4 packet units, allowing you to use it according to your bowel condition.
🔴 Various symptoms caused by constipation
When stool remains in the intestines for a long time, it ferments and harmful bacteria increase, producing harmful gases. These gases are absorbed through the intestinal wall and circulate in the body, causing rough skin and bad breath. Also, when hard stool is expelled, it can cause anal fissures or congestion of veins, leading to hemorrhoids. With Shin With One, promote soft bowel movements and improve constipation and related symptoms.
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Indications and Effects
Constipation Relief of rough skin Relief of acne Relief of heavy head Relief of hot flashes Improvement of loss of appetite Relief of abdominal bloating Abnormal intestinal fermentation Relief of hemorrhoids
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Ingredients and Content (Daily dose 3.6g, 3 packets)
| Ingredient Name | Content | Role and Action |
|---|---|---|
| Plantago Ovata Seed Husk Powder | 3,000 mg | Water-soluble dietary fiber. Swells in the intestines to increase stool bulk and promote peristalsis. |
| Sennoside (As Sennosides A and B, 32.58mg) |
83.53 mg | Herbal medicine derived from Senna. Selectively stimulates only the large intestine to promote peristalsis. |
| Cascara sagrada dry extract (Equivalent to 300mg of Designated Class 2 OTC Drug Cascara Sagrada) |
53.6 mg | Derived from the bark of Rhamnaceae plants. A supportive herbal medicine that aids intestinal function. |
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Usage and Dosage
| Age | Single dose | Timing of intake |
|---|---|---|
| Adults (15 years and older) | 3/4 to 1 packet | 1 to 3 times a day, after meals |
| 11 years old to under 15 years old | 1/2 to 2/3 packets | 1 to 3 times a day, after meals |
| 3 years old to under 11 years old | 1/4 to 1/3 packets | 1 to 3 times a day, after meals |
| Under 3 years old | Do not take if | |
💡 Dosage Advice: Take without chewing with a glass of water or lukewarm water (about 180mL).
Always start with the minimum amount for the first time, and gradually increase or decrease the dose while monitoring bowel movements.
If a child is taking this, always do so under the guidance and supervision of a guardian.
Always start with the minimum amount for the first time, and gradually increase or decrease the dose while monitoring bowel movements.
If a child is taking this, always do so under the guidance and supervision of a guardian.
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Dosage Steps
1
Take out the Stick
Open the Stick packaging and check the amount according to age and condition. Start with the minimum amount (3/4 packet for adults) for the first time.
2
Take with a full glass (about 180mL) of water
Take without chewing with water or lukewarm water. Since dietary fiber absorbs water and swells, sufficient water intake is key to effectiveness.
3
Take after meals (1 to 3 times a day)
Take after meals. Dosage can be adjusted from 1 to 3 times a day depending on bowel condition.
4
Optimize dosage while checking bowel movements
Adjust the amount little by little while monitoring your daily bowel condition to find the optimal amount for you.
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With One Series Comparison and selection
New With One ★This product
For first-time laxative users
🍫 Chocolate flavor
Dietary fiber + sennosides +
Cascara sagrada dry extract
Cascara sagrada dry extract
New With One α
Also for skin roughness caused by constipation
🍑 Peach flavor
Dietary fiber + sennosides +
Sanqilai extract (skin care)
Sanqilai extract (skin care)
With One L
For constipation with abdominal bloating
🥛 Yogurt flavor
Dietary fiber + sennosides +
Spores-containing lactic acid bacteria that reach the intestines
Spores-containing lactic acid bacteria that reach the intestines
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Frequently Asked Questions
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What are the differences from other With One series products?New With One is a "basic" formula containing Cascara sagrada dry extract, ideal for first-time users of laxatives. For those concerned about skin roughness due to constipation, "New With One α (Peach Flavor)" is recommended, and for those concerned about abdominal bloating, "With One L (Yogurt Flavor)" is recommended.
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What is Cascara sagrada?An herbal ingredient extracted from the bark of the North American Rhamnaceae plant (Cascara sagrada). Combined with dietary fiber and sennosides, it supports intestinal function and promotes gentle bowel movements.
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Why is it necessary to drink plenty of water?The main ingredient, Plantago ovata seed husk powder, is a dietary fiber that absorbs water and swells. Taking it with a full glass (about 180mL) of water allows it to swell properly in the intestines and be effective. Insufficient water intake may cause it to swell in the esophagus or stomach.
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From what age can it be used?Can be taken from age 3 and up. When children take it, always do so under the guidance and supervision of a guardian. Do not give to children under 3 years old.
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Will it cause dependence?Because it is a gentle formula based on plant ingredients, it is less likely to cause dependence compared to strong stimulant laxatives. However, if used for a long time, please consult a pharmacist or registered seller.
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Precautions for Use and Storage
⚠ Important Precautions for Use
- This is a Designated Class 2 OTC Drug. Please consult a pharmacist or registered seller before use.
- Do not give to infants under 3 years old.
- Always take with a full glass (about 180mL) of water or lukewarm water. Taking it without enough liquid is dangerous.
- If you are breastfeeding, either do not take this medicine or avoid breastfeeding while taking it.
- If you are pregnant or may be pregnant, consult a doctor or pharmacist before use.
- If symptoms do not improve or worsen, stop taking the medicine and consult a doctor or pharmacist.
- Store in a cool, dry place away from direct sunlight and out of reach of children.
- Do not take products past their expiration date.
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With One Brand Story
The plant-based laxative "With One" is a brand born with the concept of addressing women's true feelings and concerns for natural-like bowel movements.
- 1955 Founded as Zeria Yakusou Research Institute in Chuo-ku, Tokyo.
- 1970 Changed company name to Zeria Pharmaceutical Co., Ltd.
- November 1987 Launched the plant-based laxative "With One" — Japan's first full-fledged plant-based laxative.
- 2000 Listed on the First Section of the Tokyo Stock Exchange (now Prime Market).
- January 2012 Released the improved formula version "New With One." Added Cascara sagrada dry extract to further enhance support.
- Since 2012 Sequentially launched "New With One α (Peach Flavor)" and "With One L (Yogurt Flavor)," developing into a series that can be selected according to your concerns.
- ~Present Continues to be supported by a wide range of generations as a leading brand of Japanese plant-based laxatives.
⚕ This medicine should be used after consulting a pharmacist or registered seller and carefully reading the "Precautions for Use."