
Oral Boraginol® EP
For those who dislike external medicines — three herbal extracts improve blood circulation and approach hemorrhoid symptoms from inside the body
For these people and situations
Product overview
Oral Boraginol® EP is an internal medicine for hemorrhoids containing three herbal extracts: peony bark extract, horse chestnut seed extract, and Lithospermum water extract, along with vitamin E acetate. As the only oral medicine in the Boraginol® series, it works systemically to improve blood circulation and provide anti-inflammatory effects, unlike external medicines that act directly on the affected area.
Improves blood circulation disorders in the rectal and anal area worsened by straining during bowel movements or prolonged sitting, supporting relief of pain, bleeding, swelling, and itching caused by hemorrhoids and anal fissures. The stick-type individually packaged granules are easy to carry and can be taken at work, outside, or while traveling.
Product features
💊 Take orally to care for blood circulation from the inside
Approaches the root of blood circulation issues internally, which external medicines cannot easily reach. Supports hemorrhoid symptoms caused by congestion in the rectal and anal area. It does not act directly on the local area but helps relieve symptoms by improving systemic blood circulation.
🌿 Contains three herbal extracts from East and West
Peony bark Horse chestnut seed LithospermumPeony bark known as "Kuoketsu" in Oriental medicine, horse chestnut seed used in Europe for hemorrhoid treatment, and Lithospermum for mucous membrane repair. These three herbal extracts each work to improve blood flow, reduce inflammation, and protect mucous membranes.
✅ Steroid-free formulation
Formulated without steroid ingredients. While Boraginol® A series (Suppository, Ointment) contains steroids (hydrocortisone acetate), EP is steroid-free. An option for those concerned about steroids.
🎒 Convenient individually packaged for portability
Stick-type packets can be kept in bags or pockets. Unlike suppositories, no refrigeration is needed, so it can be taken during business trips, travel, or at work.
About the blended herbal extracts
Each herbal extract works on rectal and anal symptoms through different approaches.
🌸 Peony bark extract
Extracted from peony bark300 mg / per 2 packs
(Equivalent to 1,200 mg peony bark) Improves blood circulation and relieves congestion. Its anti-inflammatory effect eases pain and swelling associated with hemorrhoids. A traditional herbal medicine known as "Kuoketsu" in Oriental medicine.
🌰 Horse chestnut seed extract
Extracted from horse chestnut seeds100 mg / per 2 packs
(Equivalent to 600 mg seeds) A traditional herbal medicine used in Europe (Germany, France) for hemorrhoid treatment. Strengthens blood vessel walls and supports inflammation by improving blood circulation. Contains the active ingredient "escin."
🟣 Lithospermum water extract
Water extract from Lithospermum root300 mg / per 2 packs
(Equivalent to 900 mg Lithospermum root) Helps repair the affected mucous membrane and supports inflammation. A traditional herbal medicine used for skin and mucous membrane protection and regeneration, also effective for hemorrhoid symptoms with bleeding.
Active ingredients (per 2 packs 2g / daily dose)
| Ingredient name | Content amount | Classification | Main functions |
|---|---|---|---|
| Peony bark extract | 300 mg (Extracted from 1,200 mg of peony bark) |
Herbal extract | Blood circulation improvement, anti-inflammatory, congestion relief |
| Horse chestnut seed extract | 100 mg (Extracted from 600 mg of seeds) |
Herbal extract | Vascular strengthening, blood circulation improvement, anti-inflammatory |
| Lithospermum water extract | 300 mg (Extracted from 900 mg of Lithospermum root) |
Herbal extract | Mucous membrane repair, anti-inflammatory, and effect on bleeding symptoms |
| Vitamin E acetate (tocopherol acetate) |
100 mg | Vitamin | Promotes peripheral blood circulation and helps improve congestion |
Additives: Aspartame (L-phenylalanine compound), lactose hydrate, light anhydrous silica, cinnamon powder, carmellose sodium (CMC-Na), licorice extract
Contains aspartame (L-phenylalanine compound) as an additive. People with phenylketonuria must consult a doctor or pharmacist before taking.
Indications and effects
Target: Hemorrhoids (piles), anal fissures, hemorrhoidal bleeding
* Unlike external medicines, it alleviates hemorrhoid symptoms by improving systemic blood circulation. It does not act directly on the local area.
Dosage and administration
| Target age | How to take | Dose per time | Number of times per day |
|---|---|---|---|
| 15 years old and above (adult) | Take with water or hot water after meals | 1 pack | 2 times |
| Under 15 years old | Do not take if | ||
・Be sure to take with water or hot water after meals (avoid taking on an empty stomach).
・Granules can be carried in stick packaging and taken as is even when out.
・There are individual differences in how long it takes for effects to appear. Continued use is important.
・If symptoms do not improve after about one month of use, stop taking and consult a doctor or pharmacist.
Boraginol® series comparison
| Comparison items | EP Oral medicine [This product] |
M Ointment | M Suppository | A Suppository | A Suppository ointment | A Ointment |
|---|---|---|---|---|---|---|
| Drug classification | Class 2 OTC drug | Class 2 OTC drug | Class 2 OTC drug | Designated Class 2 OTC drug | Designated Class 2 OTC drug | Designated Class 2 OTC drug |
| Dosage form | Granules (oral) | Ointment (topical) | Suppository (topical) | Suppository (topical) | Suppository ointment (2WAY) | Ointment (topical) |
| Action pathway | Systemic (oral) | Local (topical) | Local (topical) | Local (topical) | Local (topical) | Local (topical) |
| Steroid | No ✅ | No ✅ | No ✅ | Yes ⚠️ | Yes ⚠️ | Yes ⚠️ |
| Lidocaine (local anesthetic) | No | 30mg/g | 60mg/1.75g | 60mg/1.75g | 60mg/2g | 30mg/g |
| Herbal extract | 3 types ✅ (Botampi, Horse Chestnut, Shikon) |
No | No | No | No | No |
| Sterilizing and disinfecting ingredients | No | No | No | No | No | Yes ✅ (IPMP) |
| Efficacy for bleeding | Yes ✅ (Systemic circulation improvement) |
No | No | Yes ✅ | Yes ✅ | Yes ✅ |
| Temperature control | Not required ✅ | Not required ✅ | Refrigeration recommended ⚠️ | Refrigeration recommended ⚠️ | Not required ✅ | Not required ✅ |
| Number of uses per day | 2 times (after meals) | 1 to 3 times | 1 to 2 times | 1 to 2 times | Insert 1 to 2 times Apply 1 to 3 times |
1 to 3 times |
| For these people | For those who dislike topical medicines and want to care from the inside with portability | For those who want to apply care externally without steroids | For those who want to act directly inside without steroids | For those who want to address internal hemorrhoids with bleeding | For those who want to address both internal and external symptoms and prioritize portability | For those with severe itching and who want sterilization and disinfection |
❓ Frequently Asked Questions
Q Can EP oral medicine replace topical medicines (ointment, suppository)?
A EP is an oral medicine aimed at improving systemic blood circulation and reducing inflammation, which differs from the immediate pain relief by local anesthetic (lidocaine) in topical medicines. For severe symptoms, topical medicines are expected to have a quicker effect. Sometimes they are used together, but always consult a pharmacist or registered seller beforehand.
Q Can EP be used in situations where topical medicines are difficult to use?
A EP is convenient for carrying in individual packaging in situations where topical medicines are hard to use, such as business trips or travel. However, its immediate effect differs from topical medicines. If symptoms are severe, consult a pharmacist or registered seller about using topical medicines after returning home.
Q Can I use the M series or A series topical medicines together with EP?
A Topical medicines (local action) and oral medicines (systemic action) act on different sites. If you are taking other medicines or are pregnant or breastfeeding, be sure to check with a pharmacist or doctor beforehand.
Q Can people with phenylketonuria take this medicine?
A Contains aspartame (L-phenylalanine compound) as an additive. People with phenylketonuria must consult a doctor or pharmacist before taking.
Q How long does it take for the effect to appear?
A Oral medicine helps gradually relieve symptoms by improving blood circulation. Individual results may vary, but if no improvement is seen after about one month of use, stop taking it and consult a doctor or pharmacist.
🌱 Brand Story
Founded by Tendo Pharmaceutical Co., Ltd. (Toyonaka City, Osaka Prefecture). Began as a hemorrhoid specialist manufacturer.
The Boraginol® series offers ointment and suppository types. It has built a long-standing track record as a topical medicine for hemorrhoids.
Added oral Boraginol® EP as a new selection for "care from the inside by taking it." It is the only oral medicine in the series combining traditional Eastern medicine ingredients Botampi and Shikon with the European traditional herbal seed of Horse Chestnut.
As a hemorrhoid specialist manufacturer with over 75 years of history, we continue to support symptom relief for various patients through both topical and oral medicines.
- People who have had allergic reactions to this medicine or its ingredients
- Children under 15 years old
- People receiving medical treatment
- Pregnant or possibly pregnant women, and breastfeeding women
- People who have had allergic reactions to medicines or other substances
- People with phenylketonuria (contains aspartame as an additive)
- Skin: rash, redness, itching
- Digestive system: nausea, vomiting, abdominal pain, diarrhea
- Others: dizziness
- If symptoms do not improve after about one month of use,
- Strictly follow the dosage and administration instructions.
- Be sure to take it with water or hot water after meals.
- This medicine is intended to relieve symptoms of hemorrhoids, anal fissures, and hemorrhoidal bleeding.
- Store in a cool, dry place away from direct sunlight, high temperature, and humidity.
- Keep out of reach of children.
- Do not transfer to other containers (this may cause misuse or deterioration of quality).
- Do not use products past their expiration date.














































































