
Mitake Hyakuso Pills
A bitter stomachic medicine inheriting the wisdom of Phellodendron (Ki-hada) continuing from the Jomon period

For these people and situations
For weakened stomach and intestines
Overeating, overdrinking, and the complexity of lifestyle habits can cause stress, mental fatigue, and anxiety, leading to gastrointestinal discomfort, dysfunction, and decline. When you feel stomach irregularities, it is important to normalize and protect stomach function.
Mitake Hyakuso Pills are a bitter stomachic medicine made from stomachic herbal medicines that act on the gastrointestinal tract to enhance its function and improve weak stomach, indigestion, loss of appetite, heartburn, and overdrinking. The small round tablets are about 4mm in diameter and can be used with age-appropriate dosages from 3 years old to adults.
Product Features
100% natural herbal bitter stomachic medicine
Five herbal medicines, no synthetic chemical ingredientsComposed only of five herbal medicines: Phellodendron extract as the main ingredient, Magnolia Bark, Geranium, Atractylodes, and Senburi, making it a natural stomach medicine without synthetic chemical ingredients.
Historical reliability continuing from the Jomon period
Wisdom of ancestors × modern pharmaceutical standardsPhellodendron (Ki-hada) has been found in Jomon period ruins and was used as a staple medicine by mountain ascetics in the early modern period. This formulation balances tradition with modern pharmaceutical standards.
Comprehensive action on the stomach and intestines covering a wide range of symptoms
Covers 11 symptomsFeatures a broad coverage for gastrointestinal troubles including overeating, overdrinking, heartburn, indigestion, loss of appetite, hangover nausea, and vomiting.
Usable from 3 years old, versatile for the whole family
Five age-specific dosages from 3 years to adultDosages are finely set by age, allowing the whole family from toddlers (3 years and older) to adults to use it. Small round tablets about 4mm in diameter, with five dosage levels from toddlers aged 3 to under 5 years (5 tablets per dose) to adults (20 tablets per dose). *Not for children under 3 years.
About the blended herbal medicines

Phellodendron Bark (Oubaku): A herbal medicine made from the dried bark of the deciduous tall tree of the Rutaceae family, Ki-hada. The inside is bright yellow, and the bitter component berberine promotes the secretion of gastric and digestive juices. It has a long history with records of use dating back to the Jomon period.
Magnolia Bark (Koboku): Regulates gastrointestinal movement and relieves abdominal fullness and nausea. Geranium: A representative Japanese herbal medicine with intestinal regulation effects. Atractylodes (Byakujutsu): Stomachic and diuretic effects. Senburi: A Japanese specialty bitter stomachic herb that promotes digestive juice secretion.
Ingredients and Amounts
Ingredients in 60 tablets (daily adult dose)
| Ingredient Name | Amount | Classification |
|---|---|---|
| Phellodendron Bark Extract (Equivalent raw drug amount 2,240mg) |
1,600mg | Bitter Stomachic - Main Ingredient |
| JP Magnolia Bark Powder | 700mg | Stomachic and Intestinal Regulation |
| JP Geranium Powder | 500mg | Intestinal Regulation |
| JP Atractylodes Powder | 500mg | Stomachic and Diuretic |
| JP Senburi Powder | 35mg | Bitter Stomachic |
Additives: Medicinal charcoal, hydroxypropyl cellulose, polyoxyethylene (105) polyoxypropylene (5) glycol. Since this product uses herbal medicines, the color and taste of the pills may vary slightly depending on the product, but the indications and effects remain unchanged.
Indications and Effects
Dosage and Administration
Take 3 times a day, after meals with water or warm water.
| Age | Amount per dose | Times per day |
|---|---|---|
| Adults (15 years and older) | 20 pills | 3 times |
| 11 years old to under 15 years old | 15 pills | 3 times |
| 8 years old to under 11 years old | 10 pills | 3 times |
| 5 years old to under 8 years old | 6 pills | 3 times |
| 3 years old to under 5 years old | 5 pills | 3 times |
| Under 3 years old | Do not take | |
🌱 Brand Story
Records confirm that Obaku (Amur cork tree) was already used in Jomon period ruins. Our ancestors knew the power of the bark of this Amur cork tree since ancient times.
Obaku became widely known as a common medicine for mountain ascetics. It began to be used as a protective medicine for worshippers visiting Mount Ontake (Ontake-ko) and spread nationwide under the name "Hyakuso." The "Hyakuso Origin Monument" conveys this history to the present.
Established as a representative household medicine of Shinshu under the name "Ontake Hyakuso Gan." It has been passed down from parents to children as a common household medicine and is widely loved as a Japanese gastrointestinal medicine.
Nagano Pharmaceutical Co., Ltd. has evolved the formula to meet modern pharmaceutical standards while utilizing the wisdom of predecessors, manufacturing and selling it as a Class 2 OTC Drug. As a gastrointestinal medicine that blends tradition and modern science, it continues to be loved by customers both in Japan and abroad.
❓ Frequently Asked Questions
QShould I take it before or after meals?
ATake with water or warm water after meals. It is specified to be taken after meals, not before or between meals.
QFrom what age can it be taken?
AIt can be taken from age 3. The number of pills is specified according to age (please check the usage and dosage for details). Even for children over 3 years old, be careful to prevent the medicine from getting stuck in the throat and administer under the guidance and supervision of a guardian.
QIs it okay if the color or taste of the pills is different?
ASince this product uses herbal medicine (medicinal roots, bark, etc.), the color and taste of the pills may vary slightly depending on the product, but the efficacy and effects remain the same.
QHow long should I take this?
AIf symptoms do not improve after about one month of use, stop taking the product and consult a doctor, pharmacist, or registered seller with the package insert.
- People who should consult a doctor, pharmacist, or registered seller before use: Those receiving medical treatment from a doctor.
- If symptoms do not improve: If symptoms do not improve after about one month of use, stop taking the product and consult a doctor, pharmacist, or registered seller with the package insert.
- Strictly follow the prescribed usage and dosage.
- When giving to children, administer under the guidance and supervision of a guardian.
- Do not give to infants under 3 years old.
- This product is a Class 2 OTC Drug. If you have any questions, please consult a pharmacist or registered seller.
- Store tightly closed in a cool, dry place away from direct sunlight.
- Keep out of reach of children.
- Do not transfer to other containers (this may cause misuse or change the quality).
- Do not take products past their expiration date.












































































