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Home Shop Nutritional Supplementation Heparize Plus II
ヘパリーゼ プラス Ⅱ
ヘパリーゼ プラス Ⅱ
ヘパリーゼ プラス Ⅱ
ヘパリーゼ プラス Ⅱ
ヘパリーゼ プラス Ⅱ
ヘパリーゼ プラス Ⅱ
ZERIASKU: 4987103049098

Heparize Plus II

¥363 JPY /
Shipping calculated at checkout.
Class 3 OTC Drug

selection 6 Tablet
ヘパリーゼ プラス Ⅱ
Heparize Plus II
¥363 JPY /
selection 6 Tablet
 
 
Class 3 OTC Drug Sugar-coated Tablet Zeria Pharmaceutical

Heparize Plus II

Contains liver hydrolysate. For nutrition supply during daily fatigue or digestive system discomfort.

✦ Contains 600mg liver hydrolysate ✦ Contains inositol ✦ Contains vitamin B2 and E ✦ OK before or after meals

For these people and situations

😓
For those who easily feel tired For nutrition supply when socializing or overtime work continues and you feel bodily fatigue.
🍽️
For those concerned about digestive system condition For nutrition supply when you have no appetite or feel your digestive system is not in good condition.
🏥
For those during and after illness or in recovery For nutrition supply when physical strength is reduced due to febrile wasting diseases or during and after illness.
🌸
For nutrition supply during pregnancy and breastfeeding Supports nutrition supply during periods when the body needs nourishment, such as pregnancy and breastfeeding.

Product Overview

Heparize Plus II is a Class 3 OTC Drug containing "liver hydrolysate," which is natural, high-quality liver broken down for easy digestion and absorption as its main ingredient. It activates liver metabolism and provides tonic effects. In addition to liver hydrolysate, it contains inositol to support metabolism, and vitamin B2 and vitamin E acetate ester essential for overall metabolism. This medicine supports nourishment and tonic effects for those with busy daily lives. It is designed as reddish-brown sugar-coated tablets for easy intake.

Product Features

01

Liver components in an easy-to-digest and absorb form

Liver hydrolysate

Natural, high-quality liver hydrolyzed by adding digestive enzymes and broken down into amino acids and peptides. Contains 18 types of amino acids and nucleic acid precursors, supporting metabolism.

02

Enhances metabolism

Inositol

Works together with liver hydrolysate to provide tonic effects. It is an ingredient that supports the maintenance of liver and digestive system functions.

03

Supports overall nutrition supply

Vitamin E acetate ester

Works as a fat-soluble vitamin to promote overall metabolism. The amount included has been increased compared to the previous product (New Heparize Plus).

04

Supports energy metabolism

Vitamin B2

A vitamin essential for carbohydrate, fat, and protein metabolism. Supports overall metabolism and helps with nutrition supply.

🫀 What is liver hydrolysate?

This is natural, high-quality liver hydrolyzed by adding digestive enzymes and broken down into amino acids and peptides. Since it is pre-digested in place of the human digestive system, it is in a form that is easy to digest and absorb.

🌿

Feature: Easy-to-digest and absorb form

Natural liver is hydrolyzed by adding digestive enzymes. By converting into amino acids and peptides, absorption into the body becomes smoother.

⚡

Action: 18 types of amino acids + nucleic acid precursors

Contains 18 types of amino acids including essential amino acids, and "nucleic acid precursors" necessary for cell regeneration, supporting metabolism.

😴 That fatigue might be caused by your liver or digestive system

"Even after resting, fatigue doesn't go away" or "You still feel sluggish when you wake up in the morning" — this might not just be muscle fatigue but could be caused by declining liver and digestive system function. When the liver and digestive system are tired, energy production decreases, leading to overall stamina depletion.

Diagram of the Relationship Between Liver, Digestive System, and Fatigue
🫀

Liver Fatigue

The liver plays two major roles: "metabolism" and "detoxification." When its function declines, it becomes harder to convert nutrients from food into energy, and the breakdown of harmful substances slows down, leading to fatigue and sluggishness in the body.

🫃

Fatigue of the digestive system

When the digestive and absorptive capacity of the stomach and intestines declines, food cannot be efficiently converted into nutrients. Continued nutritional deficiency reduces nutrients reaching the liver, leading to overall energy shortage and fatigue.

⚡ Main factors that burden internal organs in daily life
  • Low protein and nutritional deficiency: Energy sources for the liver are insufficient
  • Weak stomach and indigestion: Reduced nutrient absorption leads to a shortage of energy sources for the liver
  • High protein and high fat diet: The liver is burdened by processing excessive nutrients
  • Lack of exercise: Blood stagnates due to decreased detoxification and metabolism
  • Constipation: Increased detoxification burden from toxins (gas) produced in the intestines
  • Lack of sleep: The liver cannot rest and continues working, making it prone to fatigue

Active ingredients

Ingredient name Per daily dose (6 Tablets) Classification
Liver hydrolysate 600mg Tonic and metabolism
Inositol 100mg Metabolism support
Vitamin B2 (Riboflavin) 12mg Vitamin
Vitamin E acetate ester 10mg Vitamin

Efficacy and Effects

Tonic Nutritional supplementation for digestive disorders and nutritional deficiencies Nutritional supplementation during illness and recovery Nutritional supplementation during physical fatigue Nutritional supplementation during febrile wasting diseases Nutritional supplementation during pregnancy and lactation Weak constitution

Usage and Dosage

Age Amount per dose Number of times per day
Adults (15 years and older) 3 Tablets 2 times
Under 15 years old Do not take if
Can be taken before or after meals. Follow the prescribed usage and dosage.

🌱 Brand Story

1968

Zeria Pharmaceutical launched "Heparize Tablet" as a liver disorder treatment drug. Marked a new chapter in Japan's tonic market.

1979

Launched "New Heparize Tablet" containing tonic and liver hydrolysate. Full-scale expansion as a Class 3 OTC Drug.

1994

Launched "Heparize Oral Liquid" and "Heparize Drink." Expanded the lineup of easy-to-drink liquid medicines.

2015

Heparize Plus II launched. Newly formulated with inositol and increased amount of vitamin E acetate ester. Evolved to a more enriched ingredient design.

Current

The Heparize brand, with over 50 years of history, is based on the concept of "fatigue from the liver and digestive system." It continues to support the nutrition and tonic needs of busy modern people.

⚠️ Usage Precautions
  • If a rash appears on the skin after taking, it may be a side effect, so stop taking immediately and consult a doctor, pharmacist, or registered seller.
  • If symptoms do not improve after taking for a while, stop taking it and consult a doctor, pharmacist, or registered seller.
  • Follow the prescribed usage and dosage.
  • This product is a medicine. If you have any questions, please consult a pharmacist or registered seller.
📦 Storage Precautions
  • Store away from direct sunlight, high temperature, and humidity.
  • Keep out of reach of children.
  • Do not transfer to other containers (this may cause misuse or change the quality).

● Features
* Heparize Plus II is a pharmaceutical product that contains "liver hydrolysate," which is made by breaking down natural high-quality liver to make it easier to digest and absorb, as its main ingredient.
* It is effective for nutritional supplementation when you feel tired due to frequent socializing or overtime work, or when your gastrointestinal condition is not good.
* Liver hydrolysate and inositol enhance metabolism, while vitamins B2 and E work for nutritional supplementation.
* It is a reddish-brown sugar-coated tablet.

【Class 3 OTC Drug】

●Efficacy/Effects
Nutritional fortification, gastrointestinal disorders, nutritional disorders, during and after illness, physical fatigue, febrile wasting diseases, nutritional supplementation during pregnancy and lactation, and weak constitution.

<Precautions related to Efficacy/Effects>


●Dosage and Administration
Take the following single dose three times a day.
[Age: Single dose: Number of doses per day]
Adults (15 years and older): 3 Tablets: 2 times
Under 15 years: Do not take.

<Precautions related to Dosage and Administration>
(1) Follow the prescribed dosage and administration.
(2) It can be taken before or after meals.

●Ingredients/Quantity
Per 6 Tablets
Liver hydrolysate 600mg
Inositol 100mg
Vitamin B2 (Riboflavin) 12mg
Vitamin E acetate ester 10mg

〔Additives〕
D-mannitol, calcium silicate, carmellose calcium (CMC-Ca), magnesium stearate, gum arabic powder, crystalline cellulose, refined white sugar, hypromellose, pullulan, calcium sulfate, yellow iron oxide, iron oxide, red No. 3, blue No. 1, carnauba wax

<Precautions related to Ingredients/Quantity>
Urine may turn yellow after taking this medicine, but this is due to the vitamin B2 in the ingredients, so there is no need to worry.

●Dosage Form
Sugar-coated tablet (oral - tablet)

●Precautions for Use
■Consult
1. If the following symptoms appear after taking this medicine, they may be side effects. Stop taking it immediately and consult a doctor, pharmacist, or registered seller with this document.
[Affected area: Symptoms]
Skin: Rash
2. If symptoms do not improve even after taking it for a while, stop taking it and consult a doctor, pharmacist, or registered seller with this document.

●Precautions for Storage and Handling
(1) Store tightly closed in a cool, dry place away from direct sunlight.
(2) Do not store in high-temperature places. (This may cause cracks or discoloration of the tablets.)
(3) Keep out of reach of children.
(4) Do not transfer to other containers. (This may cause misuse or quality changes.)
(5) After discarding the packing material inside the bottle, be careful when handling as impact such as dropping may cause tablet damage (chipping of the sugar coating). Also, you may notice a characteristic smell of liver hydrolysate when opening.
(6) Since this medicine is a sugar-coated tablet, if moisture gets on the tablet, the sugar coating on the surface may partially dissolve, causing discoloration or unevenness. Do not handle with wet hands.
(6) Do not take the product after the expiration date.


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