Transino White C Premium
Transino White C Premium
¥2,976 JPY
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Transino® White C Premium
From inside the body. A higher-level medicine for spots and freckles.
For these people and situations
Product Overview
Transino White C Premium is an oral medicine (Class 3 OTC Drug) from the comprehensive spot care brand "Transino" by Daiichi Sankyo Healthcare, designed to reduce spots and freckles from inside the body. Since its release in 2023, it has been supported by those with deepening spot concerns and those seeking serious spot care.
Contains 2,000mg of vitamin C (adult daily dose), the maximum amount approved for vitamin C main ingredient formulations, and 240mg of L-Cysteine. Additionally, five vitamins (E, B2, B6, B3, calcium pantothenate) that keep skin healthy support spot treatment. Taking twice daily (morning and evening) works from inside the body in three steps to lighten spots.
Product Features
Contains the maximum amount of spot treatment ingredients
Vitamin C 2,000mgContains 2,000mg of vitamin C (adult daily dose), the maximum amount approved for vitamin C main ingredient formulations. This is twice the amount in the White C Clear of the same series. It works to decolorize already formed black melanin.
Contains the maximum amount of L-Cysteine
L-Cysteine 240mgL-Cysteine works with vitamin C to suppress melanin production, which causes spots and freckles. It also promotes skin metabolism and melanin discharge, helping to reduce spots, freckles, and pigmentation caused by sun exposure.
Supports care with five skin vitamins
Vitamins E, B2, B6, B3, and Calcium PantothenateFive types of vitamins—natural vitamin E (improves blood circulation), vitamins B2 and B6 (promote metabolism), nicotinamide (cell activation), and calcium pantothenate (supports vitamin C function)—help keep skin healthy and normalize turnover.
Twice daily type with less risk of forgetting daytime doses
3 Tablets each morning and eveningAdults (15 years and older) take 3 Tablets twice a day, morning and evening. This simple schedule reduces the risk of forgetting daytime doses and supports continuous care.
Cause of spots
Melanin is produced, causing spots
Ultraviolet rays stimulate melanocytes, causing excess melanin to accumulate in keratinocytes, resulting in spots.
*Image illustration
Mechanism for Spot Treatment
The mechanism by which the White C series works on spots is believed to involve the following.
1
L-Cysteine and vitamin C suppress melanin
Inside melanocytes, the amino acid tyrosine changes into melanin. Ultraviolet rays stimulate melanocytes to send signals, producing the enzyme tyrosinase, which activates tyrosine and promotes melanin formation. L-Cysteine blocks the production of tyrosinase and its activation of tyrosine.
*Image illustration
2
Vitamin C decolorizes melanin
Vitamin C has a direct reducing effect that lightens already formed melanin. It also reduces dopaquinone to its precursor dopa during melanin production in melanocytes and, like L-Cysteine, blocks tyrosinase from activating tyrosine.
*Image illustration
3
L-Cysteine, vitamins B₂ and B₆, nicotinamide (vitamin B₃), and vitamin E that improves blood circulation discharge melanin
Natural vitamin E improves blood circulation, and L-Cysteine, vitamins B₂ and B₆ promote turnover (skin metabolism), accelerating melanin discharge and maintaining normal skin function. Additionally, calcium pantothenate in White C Premium supports the action of vitamin C.
*Only Premium contains calcium pantothenate. Image illustration
Active Ingredients (per 6 Tablets)
| Ingredient Name | Content Amount | Classification |
|---|---|---|
| Ascorbic Acid (Vitamin C) | 2,000mg | Main Active Ingredient |
| L-Cysteine | 240mg | Ingredients for Spot Treatment |
| d-α-Tocopheryl Succinate (Natural Vitamin E) | 50mg | Skin Vitamins |
| Riboflavin (Vitamin B2) | 6mg | Skin Vitamins |
| Pyridoxine Hydrochloride (Vitamin B6) | 12mg | Skin Vitamins |
| Nicotinamide (Vitamin B3) | 60mg | Skin Vitamins |
| Calcium Pantothenate | 24mg | Skin Vitamins |
Additives: Corn starch, calcium lactate, lactose, carmellose, polyvinyl alcohol (partially saponified), magnesium stearate, hypromellose, titanium dioxide, talc, macrogol, carnauba wax
Efficacy & Effects
*However, if symptoms 1 and 3 above do not improve after about one month of use, consult a doctor, pharmacist, or dentist.
Dosage and Administration
Take the following amount with water or hot water.
| Age | Dose per intake | Number of doses per day |
|---|---|---|
| Adults (15 years and older) | 3 Tablets | 2 times (morning and evening) |
| Aged 7 to under 15 | 1 Tablet | 2 times (morning and evening) |
| Under 7 years old | Do not take | |
・When giving to children aged 7 and older, administer under the supervision and guidance of a guardian.
🌱 Brand Story
The Daiichi Sankyo Group focused on the effectiveness of tranexamic acid, which they developed, for melasma (a type of spot). They launched "Transino," Japan's first OTC medicine approved for melasma treatment, providing a new option for spot care.
Launched the spot and freckle treatment medicine "Transino White C Clear." The Transino brand now includes oral medicines for spot and freckle treatment.
Launched "Transino White C Premium," pursuing a more reliable effect. It contains the maximum approved amount of spot treatment ingredients and is offered as a higher-grade medicine for spots and freckles.
As a comprehensive "spot care brand" offering oral medicine and medicated skincare series, it supports spot concerns from both inside and outside the body. The total shipment of the White C series has exceeded 10 million bottles (combined total of 2 products from January 2018 to February 2025), gaining support from many people.
❓ Frequently Asked Questions
QIs it okay to take this medicine for more than one month to reduce spots?
AIf there is no improvement after taking it for more than one month, it is recommended to consult a doctor, pharmacist, or dentist. If you feel the effect, you may continue taking it, but consult a doctor, pharmacist, or registered seller if you have any concerns.
QWhen is the best time to take this medicine?
ATake twice a day, morning and evening. You can take it before or after meals, but if you have a sensitive stomach, it is recommended to take it after meals. Taking it at fixed times helps prevent forgetting.
QCan I take this medicine during pregnancy or breastfeeding?
AIf you are pregnant or breastfeeding, please consult a doctor, pharmacist, or registered seller before use. This product can also be used as a Vitamin C supplement, but it is recommended to confirm safety before use.
QDoes taking this medicine cause urine to turn yellow?
ADue to the riboflavin (Vitamin B2) included, urine may turn yellow. This is caused by the ingredient and is not a concern. Also, this medicine may affect urine and stool test results, so please inform your doctor before any medical tests.
QCan this be sent overseas by air mail?
AThis product is not classified as an aviation hazardous material under the Aviation Law. However, please check the regulations of the destination country or region before use.
- Before taking this medicine, consult a doctor, pharmacist, or registered seller if you are under medical treatment or have had allergic reactions to medicines.
- If you experience any of the following symptoms after taking this medicine, stop use and consult a doctor, pharmacist, or registered seller: skin (rash, redness, itching), digestive system (nausea, vomiting, stomach discomfort, abdominal pain).
- Diarrhea or constipation may occur after taking this medicine. If symptoms persist, stop taking it and consult.
- If symptoms do not improve after about one month of use, stop taking the medicine and consult a doctor, dentist, pharmacist, or registered seller.
- After taking this medicine, your period may come earlier than expected or bleeding may increase slightly. Please consult if bleeding continues for a long time.
- Taking this medicine may affect urine and stool test results. If you are undergoing medical tests, inform your doctor that you are taking a preparation containing Vitamin C.
- Riboflavin (Vitamin B2) may cause your urine to turn yellow.
- Follow the prescribed dosage and do not take if under 7 years old.
- If you have any questions, please consult a doctor, pharmacist, or registered seller.
- Store tightly sealed in a cool, dry place away from direct sunlight.
- Keep out of reach of children.
- Do not transfer to another container. (This may cause misuse or affect quality)
- If the container cap is not closed properly, there is a risk of deterioration due to moisture and other factors. Always make sure to close the cap tightly after each use.