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Home Shop Bestseller EVE THREE SHOT PREMIUM
エスエス製薬 イブ スリーショット プレミアム 60錠
エスエス製薬 イブ スリーショット プレミアム 30錠
エスエス製薬 イブ スリーショット プレミアム 60錠
エスエス製薬 イブ スリーショット プレミアム 30錠
SSPSKU: 4987300059814

EVE THREE SHOT PREMIUM

¥2,300 JPY /
Shipping calculated at checkout.
Designated Class 2 OTC Drug

selection 60 tablets
エスエス製薬 イブ スリーショット プレミアム 60錠
EVE THREE SHOT PREMIUM
¥2,300 JPY /
selection 60 tablets
 
 
Class 1 OTC drug Eligible for self-medication tax system No drowsiness-causing ingredients

イブ Three Shot
Premium

Firm, fast-acting pain relief. Gentle on the stomach※. Three strengths.
※Contains stomach lining protecting ingredients

🧬 Dual pain relief ingredients ⚡ Quick Action manufacturing method 🛡 Contains stomach-protecting ingredients 🚫 No drowsiness-causing ingredients

WORRIES Such concerns

🤕

Severe headache
Unable to concentrate

🌸

Menstrual pain
Too severe to move

💆

Due to shoulder stiffness pain
Unable to focus on important work

🦷

Toothache, sore throat, etc.
Troubled by various pains

MECHANISM How pain occurs and causes of dual block

Diagram of pain generation mechanism by prostaglandins and bradykinin and dual block

When prostaglandins are produced in the body, bradykinin causes pain.
Ibuprofen inhibits prostaglandin production, suppressing the source of pain in the peripheral area,
Acetaminophen eases pain transmission to the brain (central nervous system).
This dual block from two different pathways firmly addresses severe pain. (Image)

OVERVIEW Product overview

イブ スリーショットプレミアム is an antipyretic analgesic developed by SS Pharmaceutical. It contains the pain relief ingredients Ibuprofen 195mg and Acetaminophen 195mg (per adult dose), adopting a "dual pain relief ingredients※1" formula that approaches pain via two pathways: peripheral and central. The unique Quick Action manufacturing method allows magnesium oxide to speed up ibuprofen dissolution, achieving rapid pain relief onset. Furthermore, magnesium oxide also acts as a stomach lining protector, providing gentleness to the stomach. Additionally, since no drowsiness-causing ingredients are included, it can be taken without worry during work or outings. It is a Class 1 OTC drug that addresses a wide range of pains including headaches, menstrual pain, and shoulder stiffness pain.

FEATURES Four features

FEATURE 01

With dual pain relief ingredients
Double block of peripheral + central

Ibuprofen 195mg suppresses prostaglandin production in the peripheral area. Acetaminophen 195mg suppresses pain transmission in the central nervous system. These two different mechanisms strongly block pain.

Diagram of dual pain relief ingredients’ action (Acetaminophen, Ibuprofen, Magnesium oxide)
FEATURE 02

With Quick Action manufacturing method
Works quickly

Adopts the unique "Quick Action manufacturing method." Magnesium oxide speeds up the dissolution of ibuprofen, enabling rapid onset of pain relief.

Quick Action manufacturing method: Dissolution image diagram of magnesium oxide
FEATURE 03

Contains stomach-protecting ingredients +
No drowsiness-causing ingredients

Magnesium oxide protects the stomach lining, providing gentleness to the stomach. Additionally, since no drowsiness-causing ingredients are included, it can be taken safely during daytime activities.

Contains stomach-protecting ingredients; no drowsiness-causing ingredients Icon diagram
FEATURE 04

Effective for shoulder stiffness pain
Wide-ranging pain relief effect

Not only effective for headaches and menstrual pain, but also addresses various pain causes such as shoulder stiffness, joint pain, muscle pain, lower back pain, and toothache caused by prostaglandins. Supports all kinds of everyday pain situations.

Icon diagram effective for shoulder stiffness pain

INGREDIENTS Active ingredients (per 3 Tablets)

Ingredient name Amount Function
IbuprofenPain relief 195mg Suppresses the source of pain (prostaglandin production) in the peripheral area.
AcetaminophenPain relief 195mg Suppresses the transmission of pain in the central nervous system.
Magnesium oxideStomach protection 70mg Speeds the absorption of ibuprofen and also protects the stomach lining.
Anhydrous caffeineSupplement 65 mg Suppresses cerebral blood vessel dilation and enhances the analgesic effects of ibuprofen and acetaminophen.
Excipients: Anhydrous silica, cellulose, hydroxypropyl cellulose, hypromellose, crospovidone, macrogol, magnesium stearate, talc, titanium dioxide

EFFICACY Indications and Effects

Pain relief

Pain relief for headache, menstrual pain, stiff shoulders, toothache, sore throat, joint pain, muscle pain, neuralgia, lower back pain, pain after tooth extraction, bruises, ear pain, fracture pain, sprain pain, and trauma pain

Fever reduction

Chills (shivering due to fever) and fever reduction

DOSAGE Dosage and Administration

Limit to 2 doses per day, and take with water or lukewarm water, preferably not on an empty stomach.
Take at intervals of 6 hours or more.

Age Single dose amount Number of doses per day
Adults (15 years and older) 3 Tablets Up to 2 times
Under 15 years old × Do not take —
Precautions related to dosage and administration
  • Strictly follow the dosage and administration instructions.
  • Press the raised part of the PTP sheet containing the Tablets firmly with your fingertip to break the aluminum foil on the back, then take out and swallow. (Swallowing it as is by mistake may cause unexpected accidents such as piercing the esophageal mucosa.)

FAQ Frequently Asked Questions

If I use painkillers correctly, is the burden on the body significant?
Unless it does not suit your body, if you follow the dosage, usage, and precautions correctly, it generally does not cause a burden or tolerance on the body. However, using painkillers more than 10 days a month is generally considered overuse and may cause headaches (medication-overuse headaches), so caution is necessary. (From official website information)
I am worried about the burden on my stomach.
Ibuprofen Three Shot Premium contains magnesium oxide to protect the stomach lining. However, since antipyretic analgesics can cause gastrointestinal disorders, it is recommended to take it preferably not on an empty stomach. (From official website information)
Can I take it while working? Will it make me drowsy?
Ibuprofen Three Shot Premium contains no ingredients that cause drowsiness, so you can take it without worry when you feel pain during work or while out. (From official website information)

CAUTION Precautions for Use / Storage Precautions

⚠️ Things you must not do (Failure to follow may worsen current symptoms or increase risk of side effects or accidents)
  • Do not use other antipyretic analgesics, cold medicines, sedatives, or motion sickness medicines while taking this product
  • Do not give to children under 15 years old
  • Do not take if you have aspirin asthma (asthma attacks triggered by non-steroidal anti-inflammatory drugs)
  • Do not use if you have had allergic reactions caused by this product
  • Do not use if you have had allergic reactions to this product or other ibuprofen-containing products
  • Do not drink alcohol before or after taking
  • Do not use for long-term continuous use
🩺 Consult (People listed below should consult a pharmacist or registered seller before taking)
  • People receiving treatment from a doctor or dentist
  • Pregnant or possibly pregnant women, breastfeeding women
  • Elderly
  • People who have had allergic reactions to medications
  • People diagnosed with: heart disease, kidney disease, liver disease, stomach or duodenal ulcers, blood disorders
  • People using the following medications: other antipyretic analgesics, cold medicines, sedatives, anticoagulants (such as warfarin potassium), diabetes treatments, gout treatments, antibiotics (quinolone class)
🏠 Storage Precautions
  • Store in a cool, dry place away from direct sunlight.
  • Keep out of reach of children.
  • Do not transfer to other containers (this may cause misuse or change the quality).
  • Do not use products past their expiration date.
*1 Ibuprofen + Acetaminophen *2 Adult single dose (3 Tablets) *3 Prostaglandin production
The content on this page is based on official manufacturer information. For product details and the latest information, please be sure to check the package insert included with the product.

Features
Eve Three Shot Premium is a formulation designed to be effective against headaches, menstrual pain, and stiff shoulder pain.
Contains two pain relieving ingredients: ibuprofen and acetaminophen
●Uses proprietary Quick Action technology that enables rapid dissolution of ibuprofen
Contains magnesium oxide (a stomach mucosa protecting ingredient) to protect the stomach, and does not contain any ingredients that make you sleepy.

[Designated Category 2 OTC drug]

●Efficacy and effectiveness
Headache, menstrual pain (period pain), stiff shoulders, toothache, sore throat, joint pain, muscle pain, neuralgia, lower back pain, pain after tooth extraction, bruises, earache, fracture pain, pain associated with sprains, pain relief from trauma, chills (chilliness due to fever), and relief from fever

<Notes regarding efficacy and effectiveness>


Dosage and Administration
Take the following dose up to twice a day, preferably with water or lukewarm water and avoid taking it on an empty stomach. There should be at least 6 hours between doses.
[Age: Single serving]
Adults (15 years and older): 3 tablets
Under 15 years old: Do not take

<Caution regarding usage and dosage>
(1) Please strictly follow the usage and dosage instructions.
(2) How to remove the tablet: Press firmly with your fingertips against the raised part of the PTP sheet containing the tablet to break the aluminum foil on the back, remove the tablet and take it. (If swallowed by mistake, it may cause an unexpected accident, such as the tablet piercing the esophageal mucosa.)

● Ingredients and quantities
In 2 tablets
Ibuprofen 195mg
Acetaminophen 195mg
Magnesium oxide 70mg
Caffeine anhydrous 65mg

[Additives]
Silica anhydride, cellulose, hydroxypropyl cellulose, hypromellose, crospovidone, macrogol, magnesium stearate, talc, titanium oxide

<Notes regarding ingredients and quantities>


Dosage form
Film-coated tablets (oral tablets)

●Precautions for use
■Things you shouldn't do
(Failure to follow these instructions may worsen current symptoms or increase the risk of side effects or accidents.)
1. The following people should not take this medicine:
(1) People who have experienced allergic symptoms due to this drug or its ingredients.
(2) People who have experienced asthma after taking this drug or other antipyretics, analgesics, or cold medicines.
(3) Children under 15 years of age.
(4) Pregnant women who are due to give birth within 12 weeks.
2. Do not take any of the following medicines while taking this drug:
Other antipyretics, analgesics, cold medicines, and sedatives
3. Do not drive or operate machinery after taking this medicine.
4. Do not use for long periods of time
■Things to consult about
1. The following people should consult with a doctor, dentist, pharmacist, or registered distributor before taking this medicine.
(1) A person receiving treatment from a doctor or dentist.
(2) Pregnant women or those thought to be pregnant.
(3) People who are breastfeeding.
(4) Elderly people.
(5) People who have experienced allergic symptoms due to medication, etc.
(6) People who have been diagnosed with the following: heart disease, kidney disease, liver disease, systemic lupus erythematosus, mixed connective tissue disease.
(7) People who have had the following diseases: gastric or duodenal ulcer, ulcerative colitis, Crohn's disease
2. If the following symptoms occur after taking this medicine, these may be side effects, so stop taking the medicine immediately and consult a doctor, dentist, pharmacist, or registered distributor with this leaflet.
[Affected area: Symptoms]
Skin: rash, redness, itching, bruising
Digestive system: nausea, vomiting, loss of appetite, stomach discomfort, stomach pain, stomatitis, heartburn, heavy stomach, gastrointestinal bleeding, abdominal pain, diarrhea, bloody stool
Neuropsychiatric: Dizziness
Circulatory system: palpitations
Respiratory: Shortness of breath
Other: Blurred vision, ringing in the ears, swelling, nosebleeds, bleeding gums, bleeding that is difficult to stop, bleeding, back pain, excessive drop in body temperature, general fatigue
In rare cases, the following serious symptoms may occur. If this occurs, consult a doctor immediately.
[Name of symptom: Symptom]
Shock (anaphylaxis): Immediately after taking the medicine, symptoms may include itchy skin, hives, hoarseness, sneezing, itchy throat, shortness of breath, palpitations, and confusion.
Stevens-Johnson syndrome: High fever, bloodshot eyes, eye discharge, sores on the lips, sore throat, widespread skin rash and redness, etc. may persist or suddenly worsen.
Toxic epidermal necrolysis, acute generalized exanthematous pustulosis: High fever, bloodshot eyes, eye discharge, sores on the lips, sore throat, widespread rash and redness on the skin, etc. may persist or suddenly worsen.
Drug hypersensitivity syndrome: Symptoms include widespread redness of the skin, generalized rash, fever, fatigue, and swelling of the lymph nodes (neck, armpits, groin, etc.).
Liver dysfunction: Symptoms include fever, itching, rash, jaundice (yellowing of the skin or whites of the eyes), brown urine, general fatigue, and loss of appetite.
Kidney damage: Symptoms include fever, rash, decreased urine output, generalized swelling, general fatigue, joint pain (pain in the joints), and diarrhea.
Aseptic meningitis: Symptoms include a severe headache accompanied by stiffness in the neck, fever, nausea, vomiting, etc. (These symptoms have been reported frequently, especially in people receiving treatment for systemic lupus erythematosus or mixed connective tissue disease.)
Myocardial infarction: squeezing chest pain, shortness of breath, cold sweat.
Cerebrovascular disorder: Symptoms such as sudden decrease or loss of consciousness, difficulty moving one side of the limbs, headache, vomiting, dizziness, difficulty speaking, and difficulty speaking may suddenly appear.
Interstitial pneumonia: When climbing stairs or exerting yourself slightly, you may experience shortness of breath, difficulty breathing, dry cough, fever, etc. These symptoms may appear suddenly or persist.
Asthma: Symptoms include wheezing, shortness of breath, etc.
Aplastic anemia: Symptoms include bruising, nosebleeds, bleeding gums, fever, pale skin and mucous membranes, fatigue, palpitations, shortness of breath, feeling unwell and dizzy, and blood in the urine.
Agranulocytosis: Sudden high fever, chills, sore throat, etc.
3. The following symptoms may occur after taking this medicine. If these symptoms persist or worsen, discontinue use and consult a doctor, pharmacist, or registered distributor with this leaflet.
Constipation, drowsiness
4. If symptoms do not improve after taking the medicine 3 to 4 times, stop taking the medicine and consult a doctor, dentist, pharmacist, or registered distributor with this leaflet.

Storage and handling precautions
(1) Store in a cool, dry place away from direct sunlight.
(2) Keep out of reach of children.
(3) Do not transfer to other containers. (This may cause misuse or change the quality.)
(4) Do not take the medicine if it has passed its expiration date.


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