



Colac II | Taisho Pharmaceutical
A laxative with a two-ingredient formula of bisacodyl + DSS for those who want smooth bowel movements.
For these people and situations
Product Overview
“Colac II” is a “rich formula” type laxative in the Colac series manufactured and sold by Taisho Pharmaceutical. The active ingredient bisacodyl directly stimulates the large intestine to enhance peristalsis, and DSS (dioctyl sodium sulfosuccinate) penetrates water into hardened stool to soften it moderately, providing effective relief from constipation with a two-ingredient formula.
The dose per administration can be adjusted between 1 to 3 tablets (15 years and older) while monitoring bowel movements, with a recommended start at the minimum dose of 1 tablet. The bisacodyl content is higher than Colac (10 mg per 2 tablets) at 15 mg per 3 tablets, and with the addition of DSS, it offers a richer formula compared to Colac.
Product Features
Contains bisacodyl to directly stimulate the large intestine
Bisacodyl 15 mg (per 3 tablets)Bisacodyl directly stimulates peristalsis in the large intestine, activating it and enhancing reduced intestinal movement. The unique 5-layer coating ensures it reaches the large intestine without dissolving in the stomach and works effectively.
Contains DSS to soften hard stool
DSS 24 mg (per 3 tablets)DSS (Dioctyl Sodium Sulfosuccinate) penetrates water into hardened stool to soften it moderately. With a two-step approach of colon stimulation and stool softening, it creates an environment for smooth and easy bowel movements without strain.
Wide dosage range for self-adjustment
1 to 3 tablets per dose (15 years and older)You can adjust the dose between 1 to 3 tablets while monitoring bowel movements. Start with the minimum dose of 1 tablet initially and adjust gradually while checking effectiveness. Reduce dose or extend intervals once bowel movements improve.
Easy-to-swallow pink small tablets
5-Layer Coating, Small Tablet DesignDesigned as small pink tablets for easy swallowing. The active ingredients do not dissolve in the stomach but act firmly in the large intestine thanks to a special 5-layer coating. Take with water or lukewarm water without chewing.
Active Ingredients
| Ingredient Name | Content Amount (per 3 tablets) | Classification and Action |
|---|---|---|
| Bisacodyl | 15 mg | Stimulant Laxative Ingredient |
| Dioctyl Sodium Sulfosuccinate (DSS) | 24 mg | Stool Softening Ingredient |
[Additives] Lactose, Anhydrous Silica, Hydroxypropyl Cellulose, Magnesium Stearate, Gum Arabic, White Sugar, Talc, Titanium Dioxide, Methacrylic Acid Copolymer S, Methacrylic Acid Copolymer L, Castor Oil, Red No. 3, Macrogol, Carnauba Wax, Purified Beeswax
Indications and effects
Dosage and Administration
Take the following amount with water or lukewarm water before bedtime (or on an empty stomach). Start with the minimum dose initially and adjust gradually while monitoring bowel movements.
| Age | Dose per administration | Number of doses per day |
|---|---|---|
| Aged 15 and above | 1–3 Tablets | Once a day |
| 11–14 years old | 1–2 Tablets | Once a day |
| Under 11 years old | Do Not Take | |
・When giving to children, administer under the guidance and supervision of a guardian.
・Avoid taking within 1 hour after antacids (stomach medicine) or milk. (This medicine may dissolve in the stomach due to antacids or milk and not provide the expected effect.)
・Do not chew or crush the tablet; take it as is. (Damaging the special coating may reduce effectiveness.)
・Press the raised part of the PTP sheet firmly with your fingertip to break the aluminum foil on the back, then take out and take orally.
Comparison with Colac Series
| Comparison Items | [Colac II] | Colac | Colac Mg | Colac Suppository Type |
|---|---|---|---|---|
| Drug Classification | Class 2 OTC Drug | Class 2 OTC Drug | Class 3 OTC Drug | Class 3 OTC Drug |
| Dosage Form | Tablet (Oral Administration) | Tablet (Oral Administration) | Tablet (Oral Administration) | Suppository (Rectal Insertion) |
| Active Ingredients | Bisacodyl + DSS (Two Ingredients) | Bisacodyl (Single Ingredient) | Magnesium Oxide (Single Ingredient) | Sodium Bicarbonate + Anhydrous Monobasic Sodium Phosphate (Carbon Dioxide Generation) |
| Mechanism of Action | Two-step action: stimulation of the large intestine (bisacodyl) + moisture penetration into stools (DSS) | Directly stimulates the large intestine to promote peristalsis (stimulant, single ingredient) | Draws moisture into the intestines to soften stools (non-irritant) | Generates carbon dioxide in the rectum to promote intestinal movement (local action) |
| Indications and effects | Relief of constipation and associated symptoms (head heaviness, skin troubles, abdominal bloating, etc.) | Chronic and habitual constipation | Relief of constipation and associated symptoms (head heaviness, skin troubles, abdominal bloating, etc.) | Constipation |
| Stimulation to the abdomen | May cause abdominal pain | May cause abdominal pain | Less likely to cause abdominal pain | Less likely to cause abdominal pain (local rectal action) |
| Dosage adjustment | Adjustable (1–3 Tablets / 15 years and older) | Fixed (2 Tablets) | Adjustable (varies by age) | Fixed quantity (1 Tablet) |
| Onset of effect | 6–11 hours after use (individual differences apply) | 6–11 hours after use (individual differences apply) | Take before bedtime for next morning effect (individual differences apply) | About 10–30 minutes after use (fast-acting) |
| Target age | Aged 11 and above | Aged 15 and above | Aged 5 and above | Aged 12 and above |
| For these people | For those wanting strong effects with two ingredients, adjustable dosage, and smooth bowel movements | For those wanting strong effects for chronic or habitual constipation | For those seeking constipation medicine that is less likely to cause abdominal pain or concerned about hard stools | For those seeking fast-acting effects or who dislike oral medicine |
*This comparison is based on official information of each product. Effects may vary individually. Please check the package inserts of each product before use.
❓ Frequently Asked Questions
QWhat is the difference between Colac and Colac II?
AColac is a constipation medicine with bisacodyl as the single ingredient, effective for chronic and habitual constipation. Colac II is a two-ingredient formula adding DSS (dioctyl sodium sulfosuccinate) to bisacodyl, making it a richer formula compared to Colac. DSS softens stools by drawing moisture into them, making bowel movements smoother.
QHow many Tablets should I start with if taking for the first time?
AStart with the minimum dose of one Tablet. Adjust the dose gradually while monitoring bowel movements and condition to find the amount that suits you.
QIs it okay to use for a long time?
ABisacodyl, the main ingredient of Colac II, may cause the body to become accustomed to the active ingredient with continued use, reducing effectiveness. It is important to avoid long-term use. If symptoms do not improve after one week, stop use and consult a doctor, pharmacist, or registered seller.
QCan it be used during breastfeeding?
AColac II can be used during breastfeeding, but if the infant shows unusual symptoms such as soft stools or diarrhea, stop use and consult a doctor. Also, if constipation persists long-term despite use, visit a medical institution and be sure to inform the doctor that you are breastfeeding.
🌱 Brand Story
The "Colac" brand is a leading constipation medicine series in Japan developed by Taisho Pharmaceutical Co., Ltd. "Colac II" was developed for those seeking stronger effects, based on Colac with the single ingredient bisacodyl, adding the stool softening ingredient DSS in a two-ingredient formula. The series includes Colac, Colac II, Colac Mg, and Colac suppository types, allowing selection according to symptoms, preferences, and lifestyle, supporting many people's bowel habits.
- Do not do: Do not take other laxatives while using this product. Also, do not take in large amounts.
- Consult a doctor, pharmacist, or registered seller before use: Those receiving medical treatment / pregnant or possibly pregnant women / those with severe abdominal pain, nausea, or vomiting
- If severe abdominal pain, nausea, or vomiting occurs after taking, stop immediately and consult a doctor, pharmacist, or registered seller.
- If diarrhea symptoms persist or worsen, stop taking the product and consult a doctor, pharmacist, or registered seller.
- If symptoms do not improve after one week of use, stop taking the product and consult a doctor, pharmacist, or registered seller.
- Store in a cool, dry place away from direct sunlight.
- Keep out of reach of children.
- Do not transfer to another container (risk of misuse and quality changes).
- Do not take the product after the expiration date.
















































































