About leg cramps
"Leg cramps (komura gaeri)" refer to a condition where the calf muscles suddenly spasm and contract, causing severe pain; this is commonly described as "the calf muscle has cramped."

Effective for leg cramps and pain!
Comurecare Tablet Type
The herbal formula of Comurecare, "Shakuyaku-Kanzo-To," suppresses painful muscle contractions such as leg cramps, relieving pain and stiffness as a traditional herbal medicine.

What are the effects of "Shakuyaku-Kanzo-To"?
"Shakuyaku-Kanzo-To" normalizes the ion balance in muscles and improves leg cramps. By normalizing the ion balance in muscle tissue cells, it blocks excessive nerve transmission, suppresses excessive muscle contraction, and improves leg cramps. Additionally, "Shakuyaku-Kanzo-To" suppresses the production of pain-causing substances (prostaglandins) generated by leg cramps, effectively relieving the pain of leg cramps.

When to take Comurecare
If you feel discomfort in your legs after enjoying sports, work, or hobbies—such as your legs twitching—take Comurecare. The discomfort in your legs will quickly disappear.
For cramps and the like
Quickly penetrates muscle pain!
The anti-inflammatory analgesic ingredient felbinac penetrates the affected area to relieve muscle pain such as leg cramps, and the blood circulation promoting ingredient tocopherol acetate ester improves blood flow in the affected area where muscle contraction has caused stagnation.

- The anti-inflammatory analgesic ingredient felbinac penetrates the affected area and relieves muscle pain such as leg cramps (spasms).
- The blood circulation promoting ingredient tocopherol acetate ester improves blood flow in the affected area where circulation is stagnant.
- Contains l-menthol for a refreshing feeling.
| Poor muscle blood circulation |
Tocopherol acetate ▼ Promotes blood circulation
|
| Pain lasts a long time |
Felbinac ▼ Analgesic effect
|

Stop leg cramps right now.
Fast care without water!
A medicine that cures painful muscle cramps and spasms.
"Shakuyaku-Kanzo-To" firmly relieves muscle pain and stiffness. It is a grapefruit-flavored jelly medicine that can be taken immediately without water. The color and flavor of the jelly are derived from natural ingredients (herbal medicine).

● Features
Leg cramps, calf cramps, muscle spasms
Extracted from the maximum amount of crude drugs※1
Full dosage formulation※2
※1 Within the Japanese Pharmacopoeia Shakuyaku-Kanzo-to extract
※2 Full dosage formulation: Contains the entire amount (maximum amount) of extract extracted from the 12g formulation of Japanese Pharmacopoeia Shakuyaku-Kanzo-to
【Class 2 OTC Drug】
●Efficacy/Effects
Can be used regardless of physical strength, for the following symptoms accompanied by sudden muscle spasms and pain: calf cramps, muscle spasms, abdominal pain, lower back pain
<Precautions related to Efficacy/Effects>
●Dosage and Administration
Adults (15 years and older) 4 tablets per dose, children 7 years and older but under 15 years 2 tablets per dose, take 3 times a day before or between meals with water or hot water (Do not administer to children under 7 years)
<Precautions related to Dosage and Administration>
(1) Strictly adhere to the prescribed dosage and administration
(2) When administering to children, do so under the guidance and supervision of a guardian
● "Between meals" means "between meals" and refers to about 2 to 3 hours after eating
●Ingredients/Quantity
Per 12 tablets
Shakuyaku-Kanzo-to extract 2400mg (6g each of Peony root and Licorice)
〔Additives〕
Carboxymethyl cellulose calcium (CMC-Ca), silicon dioxide, magnesium stearate, talc, cellulose
<Precautions related to Ingredients/Quantity>
● Because this medicine uses natural products (crude drugs), the color of the tablets may vary slightly
●Dosage Form
Tablets (oral tablets)
●Precautions for Use
■Do not do (Contraindications)
(If not followed, current symptoms may worsen or side effects may occur more easily)
1. Do not take if diagnosed with the following: heart disease
2. Limit use to when symptoms are present; do not use continuously
■Consult
1. The following people should consult a doctor, pharmacist, or registered seller before taking:
(1) Those receiving medical treatment from a doctor
(2) Pregnant women or those who may be pregnant
(3) Elderly people
(4) Those with the following symptoms: swelling
(5) Those diagnosed with the following: hypertension, kidney disease
2. If the following symptoms appear after taking, they may be side effects; stop taking immediately and consult a doctor, pharmacist, or registered seller with this box.
Rarely, the following serious symptoms may occur. In such cases, seek medical attention immediately.
[Name of Symptom: Symptom]
Interstitial pneumonia: Shortness of breath or difficulty breathing when climbing stairs or exerting oneself slightly, dry cough, fever, etc., which appear suddenly or persist
Pseudoaldosteronism: Fatigue, numbness, stiffness or rigidity of hands and feet, accompanied by weakness and muscle pain, gradually worsening
Myopathy: Fatigue, numbness, stiffness or rigidity of hands and feet, accompanied by weakness and muscle pain, gradually worsening
Congestive heart failure: General fatigue, palpitations, shortness of breath, chest discomfort, chest pain, dizziness, fainting, etc.
Ventricular tachycardia: General fatigue, palpitations, shortness of breath, chest discomfort, chest pain, dizziness, fainting, etc.
Liver dysfunction: Fever, itching, rash, jaundice (yellowing of skin and whites of eyes), dark urine, general fatigue, loss of appetite, etc.
3. If symptoms do not improve after 5 to 6 doses, stop taking and consult a doctor, pharmacist, or registered seller with this box
●Precautions for Storage and Handling
(1) Store in a cool place with little humidity, away from direct sunlight
(2) Keep out of reach of children
(3) Do not transfer to other containers (may cause misuse or change quality)
(4) Do not handle this medicine with wet hands
(5) If dividing one packet for administration, fold the opening of the bag back at least twice to store the remaining medicine. Also, consume or discard the stored remaining medicine within the same day