Class 2 OTC Drug Internal medicine for hemorrhoids ✅ Steroid-free 🌿 Contains 3 types of herbal extracts Granule (packet) type
Oral Boraginol® EP
Tento Pharmaceutical / Care from inside the body by taking — three herbal extracts improve blood circulation and address the root cause of hemorrhoids
Steroid-free For pain, bleeding, swelling, and itching Take after meals, twice a day Individual packaging, easy to carry
Product overview
Oral Boraginol® EP is an internal medicine for hemorrhoids containing three herbal extracts: peony bark extract, horse chestnut seed extract, and Lithospermum water extract, along with vitamin E acetate. It improves blood circulation disorders in the rectal and anal area worsened by straining during bowel movements or prolonged sitting, relieving symptoms such as pain, bleeding, swelling, and itching caused by hemorrhoids and anal fissures. The stick-type individual packet granules are portable in bags, making it easy to take at work or on the go. It contains no steroids, making it suitable for those who are reluctant to use external steroid medicines or need care while out.
Four features
Feature 1
💊 Care from the inside by taking orally
Supports fundamental improvement of blood circulation internally, which is hard to reach with external medicines. Improves blood flow in the rectal and anal area and relieves hemorrhoid symptoms caused by congestion.
Feature 2
🌿 3 types of herbal extracts
Extracts derived from peony bark, horse chestnut seed, and Lithospermum work respectively to improve blood flow, reduce inflammation, and protect mucous membranes. Made from plant-derived ingredients for peace of mind.
Feature 3
✅ Steroid-free
Because it contains no steroid ingredients, it is easy to take even for those concerned about steroids. It can be used as an alternative to the A series of external medicines.
Feature 4
🎒 Convenient individual packaging for carrying
Stick-type packets that can be carried in bags or pockets. Can be taken as is when out, at work, or traveling.
About the blended herbal medicines
Each herbal extract works on rectal and anal symptoms through different approaches.
🌸 Peony bark extract
Extracted from peony bark (root bark of peony)
300 mg / per 2 packets (equivalent to 1,200 mg peony bark)
Improves blood circulation and removes congestion. Also relieves pain and swelling associated with hemorrhoids through its anti-inflammatory effect. In traditional Eastern medicine, it has long been used as a "blood stasis remover."
🌰 Horse chestnut seed extract
Extracted from horse chestnut seeds
100 mg / per 2 packets (equivalent to 600 mg horse chestnut seeds)
A traditional herbal medicine used in Europe such as Germany and France for hemorrhoid treatment. It strengthens blood vessel walls and improves blood circulation to suppress inflammation. The active ingredient is "escin."
🟣 Lithospermum water extract
Water extract from Lithospermum root
300 mg / per 2 packets (equivalent to 900 mg Lithospermum root)
Helps repair the affected mucous membrane and suppress inflammation. A traditional herbal medicine used for skin and mucous membrane protection and regeneration, also effective for hemorrhoid symptoms with bleeding.
All ingredients (per 2 packets 2g / daily dose)
| Ingredient name | Content | Category | Main functions |
|---|---|---|---|
| Peony bark extract | 300 mg (Extracted from 1,200 mg of peony bark) |
Herbal extract | Improves blood circulation, anti-inflammatory, relieves congestion |
| Horse chestnut seed extract | 100 mg (Extracted from 600 mg of seeds) |
Herbal extract | Vascular strengthening, blood circulation improvement, anti-inflammatory |
| Lithospermum water extract | 300 mg (Extracted from 900 mg of Lithospermum root) |
Herbal extract | Mucous membrane repair, anti-inflammatory, and action on bleeding symptoms |
| Vitamin E acetate (tocopherol acetate) |
100 mg | Vitamin | Promotes peripheral blood circulation and helps improve congestion |
Additives: Aspartame (L-phenylalanine compound), lactose hydrate, light anhydrous silica, cinnamon powder, carmellose sodium (CMC-Na), licorice extract
⚠️ For people with phenylketonuria (PKU) Contains aspartame (L-phenylalanine compound) as an additive. People with phenylketonuria must consult a doctor or pharmacist before taking.
Indications and effects
Target: Hemorrhoids (piles), anal fissures, hemorrhoidal bleeding
Pain Bleeding Swelling Itching
* Unlike external medicines, it relieves hemorrhoid symptoms by improving overall blood circulation. It does not act directly on the affected area.
Dosage and administration
| Target age | How to take | Amount per dose | Number of times per day |
|---|---|---|---|
| 15 years and older (Adults) |
Take with water or hot water after meals | 1 packet | 2 times |
| Under 15 years old | Do not take | ||
💡 Points for taking
・Always take with water or hot water after meals (avoid taking on an empty stomach).
・Granules can be carried in Stick packaging and taken as is even when out.
・There are individual differences in how quickly effects appear. It is important to continue taking it.
・If symptoms do not improve after about one month of use, stop using and consult a doctor or pharmacist.
・Always take with water or hot water after meals (avoid taking on an empty stomach).
・Granules can be carried in Stick packaging and taken as is even when out.
・There are individual differences in how quickly effects appear. It is important to continue taking it.
・If symptoms do not improve after about one month of use, stop using and consult a doctor or pharmacist.
Timing of intake
After breakfast
Take 1 packet within about 30 minutes after a meal.
After dinner
Take 1 packet after dinner. Taking it before bedtime is also acceptable.
With water or hot water
Always take with water or hot water. Tea, juice, etc. are not allowed.
Even when out
Individually packaged for carrying in your bag. Can be taken as is at work or while traveling.
Boraginol® Series Comparison Table
| Comparison items | EP oral medicine (This product) |
M Ointment | M Suppository | A Suppository | A Suppository ointment | A Ointment |
|---|---|---|---|---|---|---|
| Drug classification | Class 2 OTC Drug | Class 2 OTC Drug | Class 2 OTC Drug | Designated Class 2 OTC Drug | Designated Class 2 OTC Drug | Designated Class 2 OTC Drug |
| Dosage form | Granules (oral) | Ointment (external) | Suppository (external) | Suppository (external) | Suppository ointment (2WAY) |
Ointment (external) |
| Mechanism of action | Whole body (oral) | Local (external) | Local (external) | Local (external) | Local (external) | Local (external) |
| Number of active ingredients | 4 types (herbal) | 4 types | 4 types | 4 types | 4 types | 6 types |
| Steroid | No ✅ | No ✅ | No ✅ | Yes ⚠️ 1mg/1.75g |
Yes ⚠️ 1mg/2g |
Yes ⚠️ 0.5mg/g |
| Lidocaine (Local anesthesia) |
No | 30mg/g | 60mg/1.75g | 60mg/1.75g | 60mg/2g | 30mg/g |
| Vitamin E | 100mg/2 packets ✅ | Included | Included | Included | 50mg/2g | Included |
| Herbal extract | 3 types ✅ (Button flower, Horse chestnut, Lithospermum) |
No | No | No | No | No |
| Sterilization and disinfection ingredients | No | No | No | No | No | Yes ✅ (IPMP) |
| Effect on bleeding | Yes ✅ (Whole body circulation improvement) |
No | No | Yes ✅ | Yes ✅ | Yes ✅ |
| Applicable area | Whole body (oral) | Outside and nearby | Inside (inside the anus) | Inside (inside the anus) | Internal insertion + External application |
Outside and nearby |
| Temperature control | Not required | Not required | Refrigeration recommended ⚠️ | Refrigeration recommended ⚠️ | Not required | Not required |
| Number of uses per day | 2 times (after meals) | 1 to 3 times | 1 to 2 times | 1 to 2 times | Insert 1 to 2 times Apply 1 to 3 times |
1 to 3 times |
| Long-term continuous use | Consult a doctor required | ⚠️ Not allowed About 10 days |
⚠️ Not allowed About 10 days |
⚠️ Not allowed About 10 days |
⚠️ Not allowed About 10 days |
⚠️ Not allowed About 10 days |
| Use during pregnancy | Consult a doctor required | Consult a doctor required | Consult a doctor required | Consult a doctor required | Consult a doctor required | Consult a doctor required |
| For these people | For those who dislike external medicines and want to care from the inside while carrying it | For those who want to apply care externally without using steroids | For those who want to act directly inside without using steroids | For those who want to address internal hemorrhoids with bleeding | For those with both internal and external symptoms and who prioritize portability | For those with severe itching and who also want sterilization and disinfection |
Frequently Asked Questions (Q&A)
Can EP oral medicine replace external medicines (Ointment, Suppository)?
EP is an oral medicine aimed at improving overall blood circulation and reducing inflammation, and its mechanism differs from the immediate pain relief of external medicines through local anesthesia (lidocaine). External medicines are expected to act faster if symptoms are severe. Sometimes they are used in combination with external medicines, but always consult a pharmacist or registered seller beforehand.
Can EP be used even in situations where external medicines are difficult to use?
Yes. EP is convenient for carrying in individual packets in environments where it is difficult to use external medicines, such as during business trips or travel. However, since it is less fast-acting than external medicines, if symptoms are severe, it is recommended to use external medicines in combination after returning home.
Can I use the M series or A series topical medicines together with EP?
Topical medicines (local action) and oral medicines (systemic action) act on different sites. Generally, they can be used together, but if you are taking other medications or are pregnant or breastfeeding, be sure to check with a pharmacist or doctor beforehand.
Can people with phenylketonuria take this medicine?
Contains aspartame (L-phenylalanine compound) as an additive. People with phenylketonuria must consult a doctor or pharmacist before use.
How long does it take for the effect to appear?
Oral medicines differ from topical medicines in that their effects gradually appear through improved blood circulation. Although individual differences exist, continuous use for several days to weeks is generally required. If no improvement is seen after about one month of use, stop use and consult a doctor or pharmacist.
Brand story
Tendo Pharmaceutical — Hemorrhoid specialist for over 75 years, offering the "oral" option
Tendo Pharmaceutical Co., Ltd. (Toyonaka City, Osaka Prefecture) is a hemorrhoid specialist manufacturer founded in 1948. We have added Boraginol® EP oral medicine as a new option for "care from the inside" to the Boraginol® series, which has a long track record as a topical medicine.
Botanpi (Paeonia root bark) is a traditional herbal medicine used in Eastern medicine for promoting blood circulation, European horse chestnut seeds have been used in Europe for hemorrhoid treatment, and Shikon (purple root) is a traditional herbal medicine for mucous membrane repair and anti-inflammation. This is the only oral medicine in the Boraginol® series that combines Eastern and Western traditional medicine.
Precautions for use
🚫 Do not take if you fall under the following categories
- People who have had allergic reactions to this medicine or its ingredients
- Children under 15 years old
⚠️ Consult a doctor, pharmacist, or registered seller before use
- People receiving medical treatment from a doctor
- Pregnant or suspected pregnant women, breastfeeding women
- People who have had allergic reactions to medicines or other substances
- People with phenylketonuria (contains aspartame as an additive)
⚠️ If any of the following symptoms appear after taking, stop use and consult a doctor or pharmacist
- Skin: rash, redness, itching
- Digestive system: nausea, vomiting, abdominal pain, diarrhea
- Other: dizziness
- If symptoms do not improve after about one month of use
🚫 Other precautions
- Strictly follow the dosage and administration instructions
- Always take with water or warm water after meals
- This medicine is intended to relieve symptoms of hemorrhoids such as external hemorrhoids, anal fissures, and bleeding hemorrhoids, and is not a treatment drug.
Storage and handling precautions
Avoid direct sunlight, high temperature, and humidity
Store in a cool, dry place. No temperature control is needed, and it is easy to carry.
Keep out of reach of children
To prevent accidental ingestion or misuse, keep out of reach of children.
Do not transfer to other containers
To prevent misuse and quality deterioration, store in the original packaging.
Observe the expiration date
Do not use products past their expiration date.
Consultation before purchase
💬 Please consult a pharmacist or registered seller This product is a Class 2 OTC Drug. Before purchase or use, please inform the pharmacist or registered seller of your symptoms, medical history, current medications, pregnancy status, and whether you have phenylketonuria. We will support you in choosing the most suitable product.
* The information on this page is not intended as medical advice. If symptoms are severe or do not improve over a long period, please consult a medical institution promptly. The content is based on the product packaging and accompanying documents, but product specifications may change. For the latest information, please check the attached documents or contact the manufacturer (Tendo Pharmaceutical Co., Ltd.).
Package insert