About leg cramps
"'Leg cramps (calf cramps)' refer to a condition where the calf muscles suddenly spasm and contract, causing severe pain, commonly described as 'the calf muscle in the leg has cramped.'"

Effective for leg cramps and pain!
Comurecare Tablet Type
The herbal formula of Comurecare, "Shakuyaku-Kanzo-To," suppresses painful muscle contractions such as leg cramps, relieving pain and stiffness as a traditional herbal medicine.

What are the effects of "Shakuyaku-Kanzo-To"?
"Shakuyaku-Kanzo-To" normalizes the ion balance in muscles and improves leg cramps. By normalizing the ion balance in muscle tissue cells, it blocks excessive nerve transmission, suppresses excessive muscle contraction, and improves leg cramps. Additionally, "Shakuyaku-Kanzo-To" suppresses the production of pain-causing substances (prostaglandins) generated by leg cramps, effectively relieving the pain of leg cramps.

When to take Comurecare
If you feel discomfort in your legs after enjoying sports, work, or hobbies—such as your legs twitching—take Comurecare. The discomfort in your legs will quickly disappear.
For cramps and the like
Quickly penetrates muscle pain!
The anti-inflammatory analgesic ingredient felbinac penetrates the affected area to relieve muscle pain such as leg cramps, and the blood circulation promoting ingredient tocopherol acetate ester improves blood flow in the affected area where muscle contraction has caused stagnation.

- The anti-inflammatory analgesic ingredient felbinac penetrates the affected area and relieves muscle pain such as leg cramps (spasms).
- The blood circulation promoting ingredient tocopherol acetate ester improves blood flow in the affected area where circulation is stagnant.
- Contains l-menthol for a refreshing feeling.
| Poor muscle blood circulation |
Tocopherol acetate ▼ Promotes blood circulation
|
| Pain lasts a long time |
Felbinac ▼ Analgesic effect
|

Stop leg cramps right now.
Fast care without water!
A medicine that cures painful muscle cramps and spasms.
"Shakuyaku-Kanzo-To" firmly relieves muscle pain and stiffness. It is a grapefruit-flavored jelly medicine that can be taken immediately without water. The color and flavor of the jelly are derived from natural ingredients (herbal medicine).

● Features
● This medicine treats painful leg cramps (muscle spasms) and calf cramps.
● The Kampo formula "Shakuyaku-Kanzo-To" firmly relieves muscle pain and stiffness.
● It is a full-dose formula of Shakuyaku-Kanzo-To containing the maximum amount of crude drugs※ ※Within the Japanese Pharmacopoeia Shakuyaku-Kanzo-To extract.
● Recommended for use when legs cramp during exercise or sleep.
● A grapefruit-flavored jelly dosage form that can be taken immediately without water.
● The color and flavor of the jelly are derived from natural substances (crude drugs).
【Class 2 OTC Drug】
● Efficacy/Effects
Can be used regardless of physical strength, for the following conditions involving sudden muscle spasms accompanied by pain: calf cramps, muscle spasms, abdominal pain, lower back pain.
<Precautions related to Efficacy/Effects>
● Dosage and Administration
Take the following amount by dissolving the jelly in the mouth before or between meals.
[Age: Single dose: Number of doses per day]
Adults (15 years and older): 1 packet: 3 times a day
Under 15 years: Do not take
<Precautions related to Dosage and Administration>
Strictly adhere to the prescribed dosage and administration.
● This product is a single-dose packet, so do not split the dose.
● "Between meals" means the time between meals, approximately 2 to 3 hours after eating.
● Since this is a jelly dosage form, moisture may come out.
Be careful of contents spilling when opening and taking the medicine.
● Be careful not to cut your lips on the tear-off part.
● Ingredients/Quantity
In 3 packets (33g):
Shakuyaku-Kanzo-To extract 27g (Shakuyaku 6g, Kanzo 6g each)
〔Additives〕
Citric acid, sodium citrate, carrageenan, carob bean gum, white sugar, thaumatin, sucralose, parabens, sodium benzoate, propylene glycol, flavoring
<Precautions related to Ingredients/Quantity>
● Because this medicine uses natural substances (crude drugs), the color of the jelly may vary slightly.
● Dosage Form
Jelly (oral jelly)
● Precautions for Use
■Do not do (Contraindications)
(If not followed, current symptoms may worsen or side effects may occur more easily)
1. Do not take if diagnosed with heart disease.
2. Take only when symptoms are present; do not use continuously.
■Consult
1. Consult a doctor, pharmacist, or registered seller before taking if you:
(1) Are receiving medical treatment from a doctor
(2) Are pregnant or think you may be pregnant
(3) Are elderly
(4) Have the following symptoms: swelling
(5) Have been diagnosed with: high blood pressure, kidney disease
2. If the following symptoms appear after taking, they may be side effects; stop taking immediately and consult a doctor, pharmacist, or registered seller with this document.
Rarely, the following serious symptoms may occur.
In such cases, seek medical attention immediately.
[Name of Symptom: Symptom]
Interstitial pneumonia: Shortness of breath or difficulty breathing when climbing stairs or exerting yourself slightly, dry cough, fever, etc., which appear suddenly or persist.
Pseudoaldosteronism: Fatigue, numbness, tightness, or stiffness in hands and feet, accompanied by weakness and muscle pain, gradually worsening.
Myopathy: Fatigue, numbness, tightness, or stiffness in hands and feet, accompanied by weakness and muscle pain, gradually worsening.
Congestive heart failure: General fatigue, palpitations, shortness of breath, chest discomfort, chest pain, dizziness, fainting, etc.
Ventricular tachycardia: General fatigue, palpitations, shortness of breath, chest discomfort, chest pain, dizziness, fainting, etc.
Liver dysfunction: Fever, itching, rash, jaundice (yellowing of skin and whites of eyes), dark urine, general fatigue, loss of appetite, etc.
3. If symptoms do not improve after 5 to 6 doses, stop taking and consult a doctor, pharmacist, or registered seller with this document.
●Precautions for Storage and Handling
(1) Store in a cool, dry place away from direct sunlight.
(2) Keep out of reach of children.
(3) Do not transfer to another container (may cause misuse or change quality).