Sante Medical Plus Guard EX

● Features
For stinging※1 and eye inflammation※2 caused by dryness, etc.
Contains the maximum concentration※5 of seven active ingredients※4 including corneal repair and protection components※3
Troublesome eye problems such as stinging※1 and unpleasant eye inflammation※2 may be caused in part by daily damage＊ to the cornea (surface of the eye) due to friction from contact lenses, ultraviolet rays, dryness, and other irritants.
Sante Medical Plus Guard EX contains the maximum concentration※5 of seven active ingredients including flavin adenine dinucleotide sodium (active vitamin B2) which promotes corneal repair, allantoin, panthenol which activates corneal tissue metabolism, and chondroitin sulfate ester sodium which moisturizes and protects the cornea, totaling 10 active ingredients. This eye drop repairs and protects corneal damage＊ and is effective for eye troubles such as eye inflammation※2 and prevention of eye diseases※6.
※1 Discomfort when wearing hard contact lenses
※2 Eye inflammation caused by ultraviolet rays and other light (such as snow blindness)
※3 Flavin adenine dinucleotide sodium (active vitamin B2), allantoin, chondroitin sulfate ester sodium
※4 Flavin adenine dinucleotide sodium (active vitamin B2), chondroitin sulfate ester sodium, neostigmine methyl sulfate, chlorpheniramine maleate, dipotassium glycyrrhizinate, panthenol, allantoin
※5 Maximum concentration according to the standards for approval of general ophthalmic drugs (the approval standards refer to the range of pharmaceuticals established by the Ministry of Health, Labour and Welfare to streamline approval procedures)
※6 After swimming, when dust or sweat gets into the eyes, etc.
＊ Condition where the cornea is inflamed (such as snow blindness) due to ultraviolet rays, etc.

【Class 2 OTC Drug】

●Efficacy/Effects
Eye inflammation caused by ultraviolet rays and other light (such as snow blindness), blepharitis (eyelid inflammation), prevention of eye diseases (such as after swimming, when dust or sweat gets into the eyes), eye fatigue, eye itching, blurred vision (such as when there is a lot of eye discharge), conjunctival hyperemia, discomfort when wearing hard contact lenses

＜Precautions related to Efficacy/Effects＞


●Dosage and Administration
Instill 1 to 3 drops per dose, 5 to 6 times a day.

＜Precautions related to Dosage and Administration＞
●Please observe the following precautions.
(1) Excessive use may cause abnormal glare or worsen redness.
(2) When used by children, use under the guidance and supervision of a guardian.
(3) Do not let the tip of the container touch the eyes, eyelids, or eyelashes (to prevent contamination or clouding of the solution due to eye discharge or bacteria). Do not use if the solution is cloudy.
(4) Do not use while wearing soft contact lenses.
(5) For ophthalmic use only.

●Ingredients/Quantity
Flavin adenine dinucleotide sodium 0.05%
Allantoin 0.3%
Chondroitin sulfate ester sodium 0.5%
Aminoethylsulfonic acid (taurine) 0.5%
Panthenol 0.1%
L-aspartic acid potassium 0.5%
Neostigmine methyl sulfate 0.005%
Chlorpheniramine maleate 0.03%
Dipotassium glycyrrhizinate 0.25%
Tetrahydrozoline hydrochloride 0.01%

〔Additives〕
Epsilon-aminocaproic acid, edetate sodium hydrate, chlorobutanol, geraniol, dextran, sodium hyaluronate, hydroxyethyl cellulose, benzalkonium chloride solution, polysorbate 80, d-borneol, l-menthol, isotonic agent, pH adjuster

＜Precautions related to Ingredients/Quantity＞
This product may sometimes cause a sweet taste in the mouth after instillation. This is due to dipotassium glycyrrhizinate, one of the ingredients, flowing into the mouth through the tear duct, and is not due to any abnormality in quality.

●Dosage Form
Eye drops (external use [ophthalmic and otorhinolaryngologic agent] - liquid)

●Precautions for Use
■Consult
1. Consult a doctor, pharmacist, or registered seller before use if you:
(1) Are receiving treatment from a doctor
(2) Have had allergic reactions to medicines, etc.
(3) Have any of the following symptoms:
Severe eye pain
(4) Have been diagnosed with:
Glaucoma
2. If the following symptoms appear after use, they may be side effects. Stop use immediately and consult a doctor, pharmacist, or registered seller with this document.
［Affected area: Symptoms］
Skin: rash, redness, itching
Eyes: redness, itching, swelling, stinging pain
3. Stop use and consult a doctor, pharmacist, or registered seller with this document if:
(1) Blurred vision does not improve
(2) Symptoms do not improve after 5 to 6 days of use

●Precautions for Storage and Handling
(1) Store tightly closed in a cool place away from direct sunlight. To maintain product quality, do not leave in places that become hot such as inside a car or near heating appliances. Do not use if the container is deformed or the solution leaks or deteriorates due to being left in a hot place.
(2) Keep out of reach of children.
(3) Do not transfer to other containers. (This may cause misuse or change in quality.)
(4) Do not share with others.
(5) Do not use products past the expiration date. Even within the expiration date, use as soon as possible after opening.
(6) Depending on storage conditions, crystals of ingredients may form yellow deposits around the eye dropper tip or inside the cap. In such cases, gently wipe with clean gauze before use.
(7) The yellow color of this product is due to flavin adenine dinucleotide sodium (active vitamin B2). If the solution spills during instillation and stains clothing, wash immediately with water.