Skip to content
  • ☰ Category
  • New product
  • Set product
  • Brand List
  • Blog
  • FAQ
  • Holiday Notice
MamiGo
Popular searches
Pharmaceuticals and Quasi-drugs Health Foods Food Sweets Beverages Daily necessities Beauty Catalog Featured Brand Blog Business Days Information Frequently Asked Questions FAQ What is MamiGo? Contact Us

Your cart is empty

Continue shopping
0Cart(¥0 JPY)
  • ☰ Category
    • Santen Pharmaceutical Sante Hyalein S 5ml x 2 bottles OTC Medicines and Quasi-drugs
    • 日本生物化学 キトサン 菊 350錠 Health Foods
    • ORIHIRO Purunto Konjac Jelly Pouch Apple + Grape 12 pieces Food
    • Sweets
    • Beverages
    • 日用品 Daily necessities
    • 美容 Beauty
    • 비염
      Rhinitis
    • 위장약
      Gastrointestinal Medicine
    • 정장 / 변비약
      Intestinal Regulators & Laxatives
    • 피부외용약
      Topical skin medicine
    • 진통소염제
      Pain Relief and Anti-inflammatory Medicine
    • 目薬
      Eye Drops
    • 영양보급
      Nutritional Supplementation
    • 특수의약품
      Special OTC Medicines
    • 生活習慣病
      Lifestyle-related diseases
    • 医療用品
      Medical Supplies
    • 감기약
      Cold Medicine
    • エスエス製薬 エスエス ブロン錠 60錠
      Cough and Throat Medicine
    • 해열 진통제
      Antipyretic Analgesics
    • 건강관리식품
      Health Care Foods
    • 美容・ダイエットケア食品
      Beauty and Diet Care Foods
    • バランス栄養食品
      Balanced Nutritional Food
    • 特定保健用食品
      Specified Health Food Products
    • 栄養機能食品
      Nutritional Functional Foods
    • 日本生物化学 キトサン 菊 350錠
      Functional Food with Health Claims
    • 조미료
      seasoning
    • 香辛料
      Spices
    • カレー・シチュー
      Curry / Stew
    • 간단 요리
      Easy Cooking
    • スープ
      Soup
    • 면류
      Noodles
    • 곡물류
      Grains
    • 분말류
      Powdered Products
    • 乾物類
      Dried Foods
    • 잼 / 스프레드
      Jam / Spread
    • 디저트
      Dessert
    • チョコレート
      Chocolate
    • ビスケット
      Biscuit
    • クッキー
      Cookie
    • スナック菓子
      Snack Confectionery
    • ケーキ
      Cake
    • パイ
      Pie
    • 和菓子
      Japanese Sweets
    • 米菓子
      Rice Snacks
    • 豆菓子
      Bean Snacks
    • こども菓子
      Children's Sweets
    • 飴
      Candy
    • グミ
      Gummy
    • 珍味
      Delicacies
    • 水
      Water
    • ソフトドリンク
      Soft drink
    • ノンアルコール
      Non-alcoholic
    • コーヒー
      Coffee
    • ラテ
      Latte
    • ココア
      Cocoa
    • 日本茶
      Japanese Tea
    • 紅茶
      black tea
    • 中国茶
      Chinese Tea
    • 健康茶
      Health Tea
    • 青汁
      Green Juice
    • その他の飲料
      Other Beverages
    • 家庭用医療用品
      Home Medical Supplies
    • 衛生用品
      Hygiene Products
    • 生活環境用品
      Living Environment Supplies
    • 洗剤
      Detergent
    • Kitchen Supplies
    • Cleaning Supplies
    • ベビー・マタニティ用品
      Baby & Maternity Products
    • 化粧品
      Cosmetics
    • バス用品
      Bath Products
    • ボディケア用品
      Body Care Products
    • ヘアケア用品
      Hair Care Products
    • オーラルケア用品
      Oral care products
    • エチケット用品
      Etiquette Supplies
  • New productNew
  • Set product
  • Brand List
  • Blog
  • FAQ
  • Holiday Notice
Home Smile 40 Premium DX
LION スマイル 40 プレミアム DX 15ml
LION スマイル DX シリーズ
LION スマイル 40 プレミアム DX 15ml
LION スマイル DX シリーズ
LionSKU: 4903301290377

Smile 40 Premium DX

¥1,205 JPY /
Shipping calculated at checkout.
Class 2 OTC drugs

Product name : Smile 40 Premium DX
selection 15ml
LION スマイル 40 プレミアム DX 15ml
Smile 40 Premium DX
¥1,205 JPY /
selection 15ml
 
 
Class 2 OTC Drug Eye drops Preservative-free Refreshing sensation level 4 (cool)

Smile 40 Premium DX

Eye drops with 10 active ingredients that treat eye fatigue and blurred vision caused by age and strain from the cornea

✦ Contains maximum amount of adsorptive Vitamin A ✦ 10 active ingredients ✦ Preservative-free ✦ Instill 3 to 6 times a day

For these people and situations

👁️
For those concerned about eye fatigue and blurred vision Care for age-related eye fatigue and eye fatigue or blurred vision caused by long hours of digital device use.
💻
For those who strain their eyes Supports recurring eye fatigue for those who strain their eyes with PCs, smartphones, reading, etc.
🏊
For prevention of eye diseases and hygiene care Also supports prevention of eye diseases and care for conjunctival hyperemia after swimming or when dust or sweat gets into the eyes.
👓
For hard contact lens wearers Can also be used to relieve discomfort while wearing hard contact lenses.

Product overview

Smile 40 Premium DX is a core product in Lion Corporation’s Smile DX series. It contains the maximum amount within standards (50,000 units) of “adsorptive Vitamin A (retinyl palmitate),” which supports visual function recovery by penetrating damaged corneal cells, retaining tears, and supporting corneal repair. Ten active ingredients including Vitamin E, B6, Taurine, and L-aspartic acid potassium salt provide multifaceted care for eye fatigue, inflammation, focus adjustment, redness, and itching.

No preservatives (such as benzalkonium chloride) are added; preservative effect is ensured by Lion’s unique technology (Manufacturing patent No. 5084967). Cool type with refreshing sensation level 4, characterized by a refreshing instillation feeling. Please consult a doctor, pharmacist, or registered seller if you have any questions.

Product features

01

Maximum amount of adsorptive Vitamin A included

Retinyl palmitate 50,000 units

Contains the maximum amount within standards of “adsorptive Vitamin A” that directly acts on the cornea, retains tears, and promotes corneal repair. Approaches the cause of recurring eye fatigue from the cornea (Manufacturing patent No. 5084967).

02

Multifaceted care with 10 active ingredients

Vitamin A, E, B6, Taurine, and others

Contains 10 active ingredients with effects including metabolism promotion, focus adjustment, corneal protection, anti-inflammatory and soothing, itch suppression, and redness relief. Cares for many symptoms related to eye fatigue with one bottle.

03

Preservative-free

Lion’s unique preservative effect technology

No preservatives such as benzalkonium chloride are added; Lion’s unique technology ensures preservative effect. Expiration date and storage method are the same as eye drops containing preservatives.

04

Cool type with refreshing sensation level 4

Contains l-menthol and d-borneol

Refreshing sensation level 4 for a cool feeling. Suitable for those seeking relief from eye fatigue and a refreshing sensation.

Active ingredients (per 100mL)

Ingredient name Content amount Action classification
Retinyl palmitate (Vitamin A) 50,000 units Corneal repair
d-α-Tocopherol acetate (natural Vitamin E) 0.045g Metabolism promotion
Pyridoxine hydrochloride (Vitamin B6) 0.01g Metabolism promotion
Chondroitin sulfate ester sodium 0.1g Corneal protection
Taurine 1g Metabolism promotion
L-aspartic acid potassium salt 0.8g Metabolism promotion
Neostigmine methyl sulfate 0.005g Focus adjustment
Chlorpheniramine maleate 0.03g Itch suppression
Epsilon-aminocaproic acid 1g Anti-inflammatory and soothing
Tetrahydrozoline hydrochloride 0.05g Redness relief
Additives: Boric acid, Trometamol, Edetate sodium, BHT, Polyoxyethylene hardened castor oil, Polysorbate 80, Propylene glycol, l-menthol, d-borneol, pH adjuster

Efficacy and effects

Eye fatigue Blurred vision (when there is a lot of eye discharge, etc.) Prevention of eye diseases (after swimming, when dust or sweat gets into the eyes, etc.) Conjunctival hyperemia Eye itching Blepharitis (eyelid inflammation) Keratitis caused by ultraviolet and other rays (snow blindness, etc.) Discomfort when wearing hard contact lenses

Dosage and administration

Amount per application Number of times to apply per day
1 to 3 drops 3 to 6 times
・Excessive use may cause abnormal glare or even lead to redness.
・When used by children, use under the guidance and supervision of a guardian.
・Do not let the tip of the container touch your eyes, eyelids, or eyelashes.
・Do not use while wearing soft contact lenses.
・Use only as eye drops.

Smile DX Series Comparison

Comparison items 【Smile 40
Premium DX】
Smile 40
MediClear DX
Smile The
Medical A DX
Smile The Medical
A DX Contact
Classification Class 2 OTC Drug Class 2 OTC Drug Class 3 OTC Drug Class 3 OTC Drug
Main target symptoms Eye fatigue, blurriness, redness, itching Itching, redness, blurriness Dryness, fatigue from overuse, blurriness Dryness, fatigue from overuse, blurriness
Vitamin A content 50,000 units (maximum amount) 10,000 units 50,000 units (maximum amount) 50,000 units (maximum amount)
Number of active ingredients 10 types 7 types 3 types 4 types
Anti-inflammatory ingredient Epsilon-aminocaproic acid Berberine chloride hydrate + dipotassium glycyrrhizinate (double herbal formulation) None None
Redness relief ingredient Tetrahydrozoline hydrochloride None None None
Itching suppression ingredient Chlorpheniramine maleate Chlorpheniramine maleate None None
Corneal protective ingredient Chondroitin sulfate ester sodium None None Chondroitin sulfate ester sodium
Cooling sensation Level 4 (Cool) Level 4 (Cool) Level 0 (Mild) Level 0 (Mild)
Use while wearing contacts Compatible with hard lenses only Compatible with hard lenses only Not compatible (naked eye and hard lenses only) Compatible with all contacts (except colored CL)
Preservative Additive-free Additive-free Additive-free Additive-free
For these users For those concerned about eye fatigue plus itching and redness For those particularly concerned about itching and redness For those concerned about dryness-related fatigue with naked eyes For those who want to use eye drops while wearing contacts

🌱 Brand Story

Lion Corporation's "Smile" is a long-trusted ophthalmic drug brand in Japan. We have established the "Corneal Research Institute" and continue unique research on the cornea, the key to eye health. The DX series is based on the concept of "healing from the cornea," achieving a unique formula (patented manufacturing and method) that enhances vitamin A penetration into the cornea. Additionally, Lion's unique technology provides high preservative effects without adding preservatives, pursuing a gentle formula for the eyes.

⚠️ Precautions for Use
  • Consult a doctor, pharmacist, or registered seller before use: Those receiving medical treatment. Those who have had allergic reactions to medicines. Those with severe eye pain. Those diagnosed with glaucoma.
  • If symptoms such as rash, redness, itching/redness, itching, swelling, or stinging pain appear after use, stop using immediately and consult a doctor, pharmacist, or registered seller.
  • If eye blurriness does not improve, or if symptoms do not improve after 5 to 6 days of use, discontinue use and consult a doctor, pharmacist, or registered seller.
  • Do not use while wearing soft contact lenses.
  • Excessive use may cause abnormal glare or even lead to redness.
  • Do not let the tip of the container touch your eyes, eyelids, or eyelashes (this may cause contamination or foreign matter intrusion). Do not use if the solution is cloudy.
📦 Storage Precautions
  • Avoid direct sunlight and store in a cool place as much as possible.
  • Keep out of reach of children.
  • Do not transfer to other containers (this may cause misuse or change the quality).
  • Do not use the product after the expiration date.
  • Please use as soon as possible after opening.

● Features
Eye fatigue due to age and overuse. Cures blurriness※1. ※1 When there is a lot of eye discharge, etc.
Cure recurring tired eyes from the root!
Retains tears and repairs the cornea
Contains adsorptive vitamin A to support visual function recovery
When tears decrease and the cornea is damaged, visual function declines. Eyes become easily fatigued.
Contains ingredients that cure the "painful" symptoms such as eye fatigue and inflammation
Metabolism promotion: Vitamin E, Vitamin B6, Taurine, L-aspartic acid potassium salt
Focus adjustment: Neostigmine methyl sulfate
Corneal protection: Chondroitin sulfate ester sodium
Inflammation calming: Epsilon-aminocaproic acid
Itch suppression: Chlorpheniramine maleate
Redness removal: Tetrahydrozoline hydrochloride
Manufacturing patent No. 5084967 Vitamin A-containing ophthalmic drug
Preservative-free
Smile's unique technology provides preservative effects.
Does not contain preservatives (such as benzalkonium chloride).
The expiration date and storage method can be used the same as eye drops containing preservatives.

【Class 2 OTC Drug】

●Efficacy/Effects
Eye fatigue, eye blurriness (such as when there is a lot of eye discharge), prevention of eye diseases (after swimming, when dust or sweat gets into the eyes, etc.), conjunctival congestion, eye itching, blepharitis (eyelid inflammation), eye inflammation caused by ultraviolet rays and other light (such as snow blindness), discomfort when wearing hard contact lenses

<Precautions related to Efficacy/Effects>


●Dosage and Administration
Instill 1 to 3 drops, 3 to 6 times a day.

<Precautions related to Dosage and Administration>
(1) Excessive use may cause abnormal glare or even lead to congestion.
(2) When used for children, use under the guidance and supervision of a guardian.
(3) Do not let the tip of the container touch the eyes, eyelids, or eyelashes (to prevent contamination or foreign matter mixing such as eye discharge or dust). Also, do not use if the solution is cloudy.
(4) Do not use while wearing soft contact lenses.
(5) For ophthalmic use only.

●Ingredients/Quantity
Per 100 mL
Retinol palmitate 50,000 units
d-α-Tocopherol acetate 0.045 g
Pyridoxine hydrochloride 0.01 g
Chondroitin sulfate ester sodium 0.1 g
Aminoethylsulfonic acid (Taurine) 1 g
L-aspartic acid potassium salt 0.8 g
Neostigmine methyl sulfate 0.005 g
Chlorpheniramine maleate 0.03 g
Tetrahydrozoline hydrochloride 0.01 g
Epsilon-aminocaproic acid 1 g

〔Additives〕
Boric acid, Trometamol, Edetate sodium, Dibutylhydroxytoluene (BHT), Polyoxyethylene hardened castor oil, Polysorbate 80, Propylene glycol, l-menthol, d-borneol, pH adjuster

<Precautions related to Ingredients/Quantity>


●Dosage Form
Eye drops (external use [ophthalmic and otorhinolaryngologic agent] - liquid)

●Precautions for Use
■Consult
1. Consult a doctor, pharmacist, or registered seller before use if you:
(1) Are receiving medical treatment from a doctor.
(2) Have had allergic reactions to medicines.
(3) Have the following symptoms: severe eye pain
(4) Have been diagnosed with glaucoma.
2. If the following symptoms appear after use, they may be side effects. Stop use immediately and consult a doctor, pharmacist, or registered seller with this document.
[Affected area: Symptoms]
Skin: rash, redness, itching
Eyes: congestion, itching, swelling, stinging pain
3. Stop use and consult a doctor, pharmacist, or registered seller with this document if:
(1) Eye blurriness does not improve.
(2) Symptoms do not improve after 5 to 6 days of use.

●Precautions for Storage and Handling
(1) Store tightly closed in a cool place away from direct sunlight.
To maintain quality, do not leave in high-temperature places (above 40°C) such as inside a car or near heating equipment.
(2) Keep out of reach of children.
(3) Do not transfer to other containers (may cause misuse or quality changes).
(4) Do not share with others.
(5) Do not use products past the expiration date (written on the bottom of the outer box). Even within the expiration date, use as soon as possible after opening.
(6) When instilling with the container sideways or depending on storage conditions, crystals of ingredients may adhere to the tip or cap of the container.
In such cases, gently wipe off with clean gauze before use.
(7) Contains an oxygen absorber to maintain quality.
Discard the oxygen absorber after opening the transparent film.
◇In consideration of the natural environment, no carrying bag is included.


My Account
Order Tracking
MamiGo
Shopping
  • Category List
  • Brand List
  • New product
  • Set product
Terms and Policies
  • Terms of Use
  • Notation based on the Act on Specified Commercial Transactions
  • Personal Information Handling Policy
  • Shop Information
Receive event information

We will notify you of the latest news, gifts, discount events, and more before anyone else.

American Express
Apple Pay
Google Pay
JCB
Mastercard
Shop Pay
Visa

© 2026 MamiGo, All rights reserved.