Class 2 OTC DrugEye Drops
Smile 40 Premium DX
Eye drops focused on supporting the cornea for eye fatigue and blur due to age or eye strain
✦ With adsorptive vitamin A✦ 10 active ingredients✦ Preservative-free✦ Cooling level 4 (Cool)
For people like this · Situations like these
👁️
For those concerned about eye fatigue and blur
Used for symptoms of eye fatigue and blur due to age-related tired eyes or prolonged use of digital devices.
💻
For those who strain their eyes
Used when repeated eye fatigue is a concern from straining the eyes with PCs, smartphones, reading, and similar activities.
🏊
For eye disease prevention and cleanliness care
Used for eye disease prevention after swimming or when dust or sweat gets in the eyes, and for care of conjunctival hyperemia.
👓
For hard contact lens wearers
Can also be used to help with discomfort while wearing hard contact lenses.
Product Overview
Smile 40 Premium DX is an eye drop in Lion Corporation’s Smile DX series. It contains 10 active ingredients, including adsorptive vitamin A (retinol palmitate), as well as vitamins E and B6, taurine, and potassium L-aspartate, and addresses symptoms indicated in the official indications, such as eye fatigue, blur, hyperemia, and itching. It contains no preservatives (such as benzalkonium chloride) and uses Lion’s proprietary technology to provide preservative effect. It is a cool type at cooling level 4, characterized by a refreshing application feel. If you have any questions, please consult a physician, pharmacist, or registered seller.
Product Features
01
Contains adsorptive vitamin A
Vitamin A
Formulated with retinol palmitate (vitamin A). Features an adsorptive vitamin A formulation intended to act on the cornea, help retain tears, and help condition the cornea (manufacturing patent No. 5084967).
02
Addresses multiple concerns with 10 active ingredients
10 ingredients
Contains active ingredients related to metabolism, focus adjustment, corneal protection, inflammation, itching, and hyperemia—including vitamins A, E, and B6, taurine, neostigmine methylsulfate, chlorpheniramine maleate, and tetrahydrozoline hydrochloride—in a single formula that addresses multiple symptoms associated with eye fatigue.
03
Preservative-free
Proprietary technology
Contains no preservatives such as benzalkonium chloride; preservative effect is ensured with Lion’s proprietary technology. Handle expiration dates and basic storage the same way as for eye drops that contain preservatives.
✦
Cool type at cooling level 4
Contains l-menthol and d-borneol. A cool type suited for those who want a refreshing application feel.
✦
Also for discomfort while wearing hard contact lenses
Indications include discomfort while wearing hard contact lenses (do not use while wearing soft contact lenses).
Active Ingredients (per 100 mL)
Indications
Eye fatigue
Blurred vision (e.g., when there is much eye discharge)
Prevention of eye disease (e.g., after swimming, when dust or sweat gets in the eyes)
Conjunctival hyperemia
Itchy eyes
Blepharitis (sore eyelids)
Ophthalmia due to ultraviolet or other light (e.g., snow blindness)
Discomfort while wearing hard contact lenses
Dosage and Administration
| Age |
Dose per use |
Times per day |
| Adults (and those following the directions for use) |
1–3 drops per use |
Instill 3–6 times daily |
Excessive use may cause abnormal glare or, conversely, lead to hyperemia. When used by children, use under the guidance and supervision of a guardian. Do not let the tip of the container touch the eye, eyelid, or eyelashes. Do not use while wearing soft contact lenses. Use only for instillation in the eyes.
⚠️ Precautions for Use
- Excessive use may cause abnormal glare or, conversely, lead to hyperemia.
- When used by children, use under the guidance and supervision of a guardian.
- Do not let the tip of the container touch the eye, eyelid, or eyelashes (may cause injury or contamination).
- Do not use while wearing soft contact lenses.
- Use only for instillation in the eyes.
- Before use, carefully read the package insert and confirm contraindications, matters to consult about, and storage precautions.
- If symptoms do not improve or worsen, discontinue use and consult a physician, pharmacist, or registered seller.
📦 Storage Precautions
- Store away from direct sunlight in a place that is as cool as possible.
- Store out of reach of children.
- Do not transfer to other containers.
- Do not use products past their expiration date.
- Although preservative-free, handle expiration dates and basic storage the same way as for eye drops that contain preservatives.
● Features
Eye fatigue due to age and overuse. Cures blurriness※1. ※1 When there is a lot of eye discharge, etc.
Cure recurring tired eyes from the root!
Retains tears and repairs the cornea
Contains adsorptive vitamin A to support visual function recovery
When tears decrease and the cornea is damaged, visual function declines. Eyes become easily fatigued.
Contains ingredients that cure the "painful" symptoms such as eye fatigue and inflammation
Metabolism promotion: Vitamin E, Vitamin B6, Taurine, L-aspartic acid potassium salt
Focus adjustment: Neostigmine methyl sulfate
Corneal protection: Chondroitin sulfate ester sodium
Inflammation calming: Epsilon-aminocaproic acid
Itch suppression: Chlorpheniramine maleate
Redness removal: Tetrahydrozoline hydrochloride
Manufacturing patent No. 5084967 Vitamin A-containing ophthalmic drug
Preservative-free
Smile's unique technology provides preservative effects.
Does not contain preservatives (such as benzalkonium chloride).
The expiration date and storage method can be used the same as eye drops containing preservatives.
【Class 2 OTC Drug】
●Efficacy/Effects
Eye fatigue, eye blurriness (such as when there is a lot of eye discharge), prevention of eye diseases (after swimming, when dust or sweat gets into the eyes, etc.), conjunctival congestion, eye itching, blepharitis (eyelid inflammation), eye inflammation caused by ultraviolet rays and other light (such as snow blindness), discomfort when wearing hard contact lenses
＜Precautions related to Efficacy/Effects＞
●Dosage and Administration
Instill 1 to 3 drops, 3 to 6 times a day.
＜Precautions related to Dosage and Administration＞
(1) Excessive use may cause abnormal glare or even lead to congestion.
(2) When used for children, use under the guidance and supervision of a guardian.
(3) Do not let the tip of the container touch the eyes, eyelids, or eyelashes (to prevent contamination or foreign matter mixing such as eye discharge or dust). Also, do not use if the solution is cloudy.
(4) Do not use while wearing soft contact lenses.
(5) For ophthalmic use only.
●Ingredients/Quantity
Per 100 mL
Retinol palmitate 50,000 units
d-α-Tocopherol acetate 0.045 g
Pyridoxine hydrochloride 0.01 g
Chondroitin sulfate ester sodium 0.1 g
Aminoethylsulfonic acid (Taurine) 1 g
L-aspartic acid potassium salt 0.8 g
Neostigmine methyl sulfate 0.005 g
Chlorpheniramine maleate 0.03 g
Tetrahydrozoline hydrochloride 0.01 g
Epsilon-aminocaproic acid 1 g
〔Additives〕
Boric acid, Trometamol, Edetate sodium, Dibutylhydroxytoluene (BHT), Polyoxyethylene hardened castor oil, Polysorbate 80, Propylene glycol, l-menthol, d-borneol, pH adjuster
＜Precautions related to Ingredients/Quantity＞
●Dosage Form
Eye drops (external use [ophthalmic and otorhinolaryngologic agent] - liquid)
●Precautions for Use
■Consult
1. Consult a doctor, pharmacist, or registered seller before use if you:
(1) Are receiving medical treatment from a doctor.
(2) Have had allergic reactions to medicines.
(3) Have the following symptoms: severe eye pain
(4) Have been diagnosed with glaucoma.
2. If the following symptoms appear after use, they may be side effects. Stop use immediately and consult a doctor, pharmacist, or registered seller with this document.
［Affected area: Symptoms］
Skin: rash, redness, itching
Eyes: congestion, itching, swelling, stinging pain
3. Stop use and consult a doctor, pharmacist, or registered seller with this document if:
(1) Eye blurriness does not improve.
(2) Symptoms do not improve after 5 to 6 days of use.
●Precautions for Storage and Handling
(1) Store tightly closed in a cool place away from direct sunlight.
To maintain quality, do not leave in high-temperature places (above 40°C) such as inside a car or near heating equipment.
(2) Keep out of reach of children.
(3) Do not transfer to other containers (may cause misuse or quality changes).
(4) Do not share with others.
(5) Do not use products past the expiration date (written on the bottom of the outer box). Even within the expiration date, use as soon as possible after opening.
(6) When instilling with the container sideways or depending on storage conditions, crystals of ingredients may adhere to the tip or cap of the container.
In such cases, gently wipe off with clean gauze before use.
(7) Contains an oxygen absorber to maintain quality.
Discard the oxygen absorber after opening the transparent film.
◇In consideration of the natural environment, no carrying bag is included.
