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Home Shop New product EVE THREE SHOT PREMIUM
エスエス製薬 イブ スリーショット プレミアム 60錠
エスエス製薬 イブ スリーショット プレミアム 30錠
エスエス製薬 イブ スリーショット プレミアム 60錠
エスエス製薬 イブ スリーショット プレミアム 30錠
SSPSKU: 4987300059814

EVE THREE SHOT PREMIUM

¥2,300 JPY /
Shipping calculated at checkout.
Designated Class 2 OTC Drug

selection 60 tablets
エスエス製薬 イブ スリーショット プレミアム 60錠
EVE THREE SHOT PREMIUM
¥2,300 JPY /
selection 60 tablets
 
 
Designated Class 2 OTC Drug Eligible for the Self-Medication Tax Deduction No drowsiness-causing ingredients

Eve Three Shot
Premium

Works effectively and quickly on pain. Gentle on the stomach※. Three strengths.
※Contains a stomach-lining-protecting ingredient

🧬 Dual pain-relieving ingredients ⚡ Quick Action formulation 🛡 Contains a stomach-protecting ingredient 🚫 No drowsiness-causing ingredients

WORRIES Common concerns

🤕

Due to a severe headache
Unable to concentrate

🌸

Menstrual pain
So severe you cannot move

💆

Due to shoulder stiffness pain
Unable to focus on important work

🦷

Toothache, sore throat, and more
Suffering from various types of pain

MECHANISM How pain occurs and the cause of the dual block

Illustration of the pain-generation mechanisms of prostaglandins and bradykinin and the dual block

and when prostaglandins are produced in the body, bradykinin causes pain.
Ibuprofen inhibits prostaglandin production to suppress the source of pain in peripheral tissues,
Acetaminophen eases the transmission of pain to the brain (central nervous system).
This dual block through two different pathways effectively addresses severe pain. (Illustration)

OVERVIEW Product overview

Eve Three Shot Premium is an antipyretic analgesic developed by SS Pharmaceutical. It contains the pain-relieving ingredients ibuprofen 195mg and acetaminophen 195mg (per adult dose), using a "dual pain-relieving ingredient※1" formulation that approaches pain through two pathways: peripheral and central. With its proprietary Quick Action formulation, magnesium oxide speeds up the dissolution of ibuprofen, enabling rapid pain relief to take effect. Magnesium oxide also works as a stomach-lining-protecting ingredient, helping to provide gentler effects on the stomach. In addition, because it contains no drowsiness-causing ingredients, you can take it without concern while working or out and about. It is a Class 1 OTC drug for a wide range of pain, including headaches, menstrual pain, and shoulder stiffness pain.

FEATURES Four features

FEATURE 01

With dual pain-relieving ingredients
Double block: peripheral + central

Ibuprofen 195mg suppresses prostaglandin production in peripheral tissues. Acetaminophen 195mg suppresses pain transmission in the central nervous system. The two different mechanisms of action powerfully block pain.

Illustration of the dual action of pain-relieving ingredients (acetaminophen, ibuprofen, magnesium oxide)
FEATURE 02

With the Quick Action formulation
Works fast

It uses the proprietary "Quick Action formulation." Magnesium oxide speeds up the dissolution of ibuprofen, enabling rapid pain relief to take effect.

Quick Action formulation: illustration of magnesium oxide's effect on dissolution
FEATURE 03

Contains a stomach-protecting ingredient +
No drowsiness-causing ingredients

Magnesium oxide protects the stomach lining for gentler effects on the stomach. In addition, because it contains no drowsiness-causing ingredients, you can take it with confidence during the day.

Contains a stomach-protecting ingredient and no drowsiness-causing ingredients - illustrated icon
FEATURE 04

Effective for shoulder stiffness pain
Wide-ranging pain relief

Not only headaches and menstrual pain, but also shoulder stiffness pain, joint pain, muscle pain, lower back pain, toothache, and more - it targets prostaglandins, the cause of various types of pain. It supports you through all kinds of everyday pain.

Effective for shoulder stiffness pain - illustrated icon

INGREDIENTS Active ingredients (per 3 tablets)

Ingredient name Amount Functions
IbuprofenPain relief 195mg Suppresses the production of the source of pain (prostaglandins) in the peripheral tissues.
AcetaminophenPain relief 195mg Suppresses the transmission of pain through the central nervous system.
Magnesium oxideStomach protection 70mg Speeds up the absorption of ibuprofen and protects the stomach lining.
Anhydrous caffeineAuxiliary 65 mg Suppresses the dilation of cerebral blood vessels and helps the analgesic effects of ibuprofen and acetaminophen.
Inactive ingredients: colloidal anhydrous silica, cellulose, hydroxypropyl cellulose, hypromellose, crospovidone, macrogol, magnesium stearate, talc, titanium dioxide

EFFICACY Indications

Pain relief

Relief of headaches, menstrual pain, shoulder stiffness pain, toothache, throat pain (sore throat), joint pain, muscle pain, neuralgia, lower back pain, pain after tooth extraction, bruising pain, earache, fracture pain, sprain-related pain, and pain from injuries

Fever reduction

Relief of chills (feeling cold due to fever) and fever

DOSAGE Directions and Dosage

Take the following dose up to twice daily, avoiding an empty stomach as much as possible, with water or lukewarm water.
Leave an interval of at least 6 hours between doses.

Age Dose per use Number of doses per day
Adults (15 years and older) 3 Tablets Up to 2 times
Under 15 years of age × Do not take —
Precautions Related to Directions and Dosage
  • Strictly follow the directions and dosage.
  • Press the raised part of the PTP sheet containing the Tablets firmly with your fingertip to break the aluminum foil on the back, then remove and take the Tablet. (Accidentally swallowing it whole may cause unexpected accidents, such as it becoming lodged in the esophageal lining.)

FAQ Frequently Asked Questions

If analgesics are used correctly, do they place a significant strain on the body?
Except when the medicine does not suit you, if you use it correctly according to the directions, dosage, and precautions for use, it generally causes little strain on the body and does not usually lead to tolerance. However, using analgesics for 10 or more days per month is generally considered overuse and may cause headaches such as medication-overuse headaches, so caution is needed. (Based on information published on the official website.)
I am concerned about the strain on my stomach.
EVE Three Shot Premium contains magnesium oxide, which protects the stomach lining. However, some antipyretic analgesic ingredients can cause gastrointestinal problems, so we recommend taking it while avoiding an empty stomach as much as possible. (Based on information published on the official website.)
Can I take it while working? Will it make me drowsy?
EVE Three Shot Premium contains no ingredients that cause drowsiness, so you can take it without concern when you feel pain at work or while out. (Based on information published on the official website.)

CAUTION Precautions for Use / Storage Precautions

⚠️ Do not do this (failure to follow these instructions may worsen current symptoms or make side effects and accidents more likely)
  • While taking this medicine, do not use other antipyretic analgesics, cold medicines, sedatives, or motion sickness medicines.
  • Do not take if under 15 years of age.
  • Do not take this medicine if you have aspirin-induced asthma (asthma attacks triggered by nonsteroidal anti-inflammatory analgesics or similar medicines).
  • Do not use this medicine if you have experienced allergic symptoms caused by this medicine.
  • Do not use this medicine if you have experienced allergic symptoms after taking this medicine or other ibuprofen-containing products.
  • Do not drink alcohol before or after taking this medicine.
  • Do not use for an extended period.
🩺 Consult a healthcare professional (the following people should consult a pharmacist or registered salesperson before taking this medicine)
  • People receiving treatment from a doctor or dentist
  • Pregnant people or those who may be pregnant, and people who are breastfeeding
  • Elderly
  • People who have experienced allergic symptoms caused by medicines or other products
  • People diagnosed with any of the following: heart disease, kidney disease, liver disease, gastric or duodenal ulcers, blood disorders
  • People using the following medicines: other antipyretic analgesics, cold medicines, sedatives, anticoagulants (such as warfarin potassium), diabetes medicines, gout medicines, antibacterial medicines (new quinolones)
🏠 Storage Precautions
  • Store in a cool, low-humidity place away from direct sunlight.
  • Keep out of reach of children.
  • Do not transfer the product to another container (this may lead to misuse or changes in quality).
  • Do not use the product after its expiration date.
*1 Ibuprofen + acetaminophen *2 Per adult dose (3 Tablets) *3 Refers to the production of prostaglandins
The contents of this page are based on official manufacturer information. For product details and the latest information, be sure to check the package insert included with the product.

Features
Eve Three Shot Premium is a formulation designed to be effective against headaches, menstrual pain, and stiff shoulder pain.
Contains two pain relieving ingredients: ibuprofen and acetaminophen
●Uses proprietary Quick Action technology that enables rapid dissolution of ibuprofen
Contains magnesium oxide (a stomach mucosa protecting ingredient) to protect the stomach, and does not contain any ingredients that make you sleepy.

[Designated Category 2 OTC drug]

●Efficacy and effectiveness
Headache, menstrual pain (period pain), stiff shoulders, toothache, sore throat, joint pain, muscle pain, neuralgia, lower back pain, pain after tooth extraction, bruises, earache, fracture pain, pain associated with sprains, pain relief from trauma, chills (chilliness due to fever), and relief from fever

<Notes regarding efficacy and effectiveness>


Dosage and Administration
Take the following dose up to twice a day, preferably with water or lukewarm water and avoid taking it on an empty stomach. There should be at least 6 hours between doses.
[Age: Single serving]
Adults (15 years and older): 3 tablets
Under 15 years old: Do not take

<Caution regarding usage and dosage>
(1) Please strictly follow the usage and dosage instructions.
(2) How to remove the tablet: Press firmly with your fingertips against the raised part of the PTP sheet containing the tablet to break the aluminum foil on the back, remove the tablet and take it. (If swallowed by mistake, it may cause an unexpected accident, such as the tablet piercing the esophageal mucosa.)

● Ingredients and quantities
In 2 tablets
Ibuprofen 195mg
Acetaminophen 195mg
Magnesium oxide 70mg
Caffeine anhydrous 65mg

[Additives]
Silica anhydride, cellulose, hydroxypropyl cellulose, hypromellose, crospovidone, macrogol, magnesium stearate, talc, titanium oxide

<Notes regarding ingredients and quantities>


Dosage form
Film-coated tablets (oral tablets)

●Precautions for use
■Things you shouldn't do
(Failure to follow these instructions may worsen current symptoms or increase the risk of side effects or accidents.)
1. The following people should not take this medicine:
(1) People who have experienced allergic symptoms due to this drug or its ingredients.
(2) People who have experienced asthma after taking this drug or other antipyretics, analgesics, or cold medicines.
(3) Children under 15 years of age.
(4) Pregnant women who are due to give birth within 12 weeks.
2. Do not take any of the following medicines while taking this drug:
Other antipyretics, analgesics, cold medicines, and sedatives
3. Do not drive or operate machinery after taking this medicine.
4. Do not use for long periods of time
■Things to consult about
1. The following people should consult with a doctor, dentist, pharmacist, or registered distributor before taking this medicine.
(1) A person receiving treatment from a doctor or dentist.
(2) Pregnant women or those thought to be pregnant.
(3) People who are breastfeeding.
(4) Elderly people.
(5) People who have experienced allergic symptoms due to medication, etc.
(6) People who have been diagnosed with the following: heart disease, kidney disease, liver disease, systemic lupus erythematosus, mixed connective tissue disease.
(7) People who have had the following diseases: gastric or duodenal ulcer, ulcerative colitis, Crohn's disease
2. If the following symptoms occur after taking this medicine, these may be side effects, so stop taking the medicine immediately and consult a doctor, dentist, pharmacist, or registered distributor with this leaflet.
[Affected area: Symptoms]
Skin: rash, redness, itching, bruising
Digestive system: nausea, vomiting, loss of appetite, stomach discomfort, stomach pain, stomatitis, heartburn, heavy stomach, gastrointestinal bleeding, abdominal pain, diarrhea, bloody stool
Neuropsychiatric: Dizziness
Circulatory system: palpitations
Respiratory: Shortness of breath
Other: Blurred vision, ringing in the ears, swelling, nosebleeds, bleeding gums, bleeding that is difficult to stop, bleeding, back pain, excessive drop in body temperature, general fatigue
In rare cases, the following serious symptoms may occur. If this occurs, consult a doctor immediately.
[Name of symptom: Symptom]
Shock (anaphylaxis): Immediately after taking the medicine, symptoms may include itchy skin, hives, hoarseness, sneezing, itchy throat, shortness of breath, palpitations, and confusion.
Stevens-Johnson syndrome: High fever, bloodshot eyes, eye discharge, sores on the lips, sore throat, widespread skin rash and redness, etc. may persist or suddenly worsen.
Toxic epidermal necrolysis, acute generalized exanthematous pustulosis: High fever, bloodshot eyes, eye discharge, sores on the lips, sore throat, widespread rash and redness on the skin, etc. may persist or suddenly worsen.
Drug hypersensitivity syndrome: Symptoms include widespread redness of the skin, generalized rash, fever, fatigue, and swelling of the lymph nodes (neck, armpits, groin, etc.).
Liver dysfunction: Symptoms include fever, itching, rash, jaundice (yellowing of the skin or whites of the eyes), brown urine, general fatigue, and loss of appetite.
Kidney damage: Symptoms include fever, rash, decreased urine output, generalized swelling, general fatigue, joint pain (pain in the joints), and diarrhea.
Aseptic meningitis: Symptoms include a severe headache accompanied by stiffness in the neck, fever, nausea, vomiting, etc. (These symptoms have been reported frequently, especially in people receiving treatment for systemic lupus erythematosus or mixed connective tissue disease.)
Myocardial infarction: squeezing chest pain, shortness of breath, cold sweat.
Cerebrovascular disorder: Symptoms such as sudden decrease or loss of consciousness, difficulty moving one side of the limbs, headache, vomiting, dizziness, difficulty speaking, and difficulty speaking may suddenly appear.
Interstitial pneumonia: When climbing stairs or exerting yourself slightly, you may experience shortness of breath, difficulty breathing, dry cough, fever, etc. These symptoms may appear suddenly or persist.
Asthma: Symptoms include wheezing, shortness of breath, etc.
Aplastic anemia: Symptoms include bruising, nosebleeds, bleeding gums, fever, pale skin and mucous membranes, fatigue, palpitations, shortness of breath, feeling unwell and dizzy, and blood in the urine.
Agranulocytosis: Sudden high fever, chills, sore throat, etc.
3. The following symptoms may occur after taking this medicine. If these symptoms persist or worsen, discontinue use and consult a doctor, pharmacist, or registered distributor with this leaflet.
Constipation, drowsiness
4. If symptoms do not improve after taking the medicine 3 to 4 times, stop taking the medicine and consult a doctor, dentist, pharmacist, or registered distributor with this leaflet.

Storage and handling precautions
(1) Store in a cool, dry place away from direct sunlight.
(2) Keep out of reach of children.
(3) Do not transfer to other containers. (This may cause misuse or change the quality.)
(4) Do not take the medicine if it has passed its expiration date.


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