Papinarin
For prolonged and recurring ear pain and itching. The only ear drop type OTC ear medicine approved in Japan.
For these people and situations
Product overview
Papinarin is a Liquid ear drop medicine (Class 2 OTC Drug) manufactured and sold by Harasawa Pharmaceutical Industry exclusively for ears. By applying directly inside the ear, it cares for symptoms such as ear pain, itching, tinnitus, ear discharge, external auditory canal inflammation, and otitis media through the dual action of analgesic and bactericidal ingredients.
An ear drop medicine approved as the only Class 2 OTC Drug in Japan with efficacy for external auditory canal inflammation (since July 10, 2007). The predecessor Papirogin was launched in 1949 and has been loved for over 70 years with an unchanged formula. Supports multiple usage methods such as ear drops, cotton wool, and cotton swabs according to symptoms and age.
Product features
Analgesic effect to care for ear pain
Ethyl aminobenzoate, procaine hydrochlorideTwo analgesic ingredients with surface and local anesthetic effects help relieve ear pain and tinnitus.
Bactericidal action against causative bacteria
Phenol, acrinol hydrate, homosulfamineContains three bactericidal and antibacterial ingredients that act against bacteria causing otitis externa and otitis media.
The only approved OTC ear drop for otitis externa in Japan
Effective for external auditory canal inflammation (otitis externa)The only ear drop medicine approved in Japan as a Class 2 OTC Drug with efficacy for external auditory canal inflammation (since July 10, 2007).
Over 70 years of proven results and unchanged formula
Launched in 1949 - Long sellerThe trusted formula has been loved for over 70 years without change since the predecessor "Papirogin" was launched in 1949.
Active ingredients
| Ingredient name | Content (per 100g) | Classification and function |
|---|---|---|
| Phenol | 2.00g | Bactericidal and antipruritic |
| Ethyl aminobenzoate | 0.30g | Analgesic and surface anesthetic |
| Procaine hydrochloride | 0.30g | Local anesthesia and analgesia |
| Acrinol hydrate | 0.10g | Bactericidal (Gram-positive and Gram-negative bacteria) |
| Homosulfamine | 0.10g | Antibacterial and purulent diseases |
Efficacy and effects
Dosage and administration
| Usage method | How to use per application | Frequency of use |
|---|---|---|
| ① Ear drops (for both adults and children) | Lie down with the ear facing up and apply 1 to 3 drops with a dropper. | 1 to 2 times a day |
| ② When using cotton wool | Roll a small amount of cotton wool to the size of a red bean, soak it in the medicine, and insert it at the entrance of the ear with tweezers. | 1 to 2 times a day |
| ③ When using for children | Soak a small amount of medicine on a cotton swab and lightly apply to the entrance of the ear. | 1 to 2 times a day |
❓ Frequently Asked Questions
Q Does it cause drowsiness?
A Papinarin does not contain ingredients that cause drowsiness.
Q Can I continue using it?
A If effective and no side effects appear, continuous use is possible. However, as a Class 2 OTC Drug, avoid using it indiscriminately for more than one month. Use only when symptoms are present.
Q How long does it take to see effects?
A Some people see effects in 5 to 6 days for ear pain, but it varies depending on constitution and symptoms. If symptoms do not improve after 5 to 6 days of use, stop using and consult a doctor, pharmacist, or registered seller.
Q Can it be used for children's ear symptoms?
A It can also be used for children's ear pain. Caregivers should lightly apply a small amount of the liquid medicine soaked on a cotton swab to the entrance of the ear.
Q Is Papinarin the only OTC medicine that can be used for external auditory canal inflammation (otitis externa)?
A Yes. Papinarin is the only Class 2 OTC Drug ear drop medicine with efficacy for external auditory canal inflammation (otitis externa).
🌱 Brand Story
Founded as "Harasawa Mercury Research Institute," the predecessor of Harasawa Pharmaceutical Industry. The journey of pharmaceutical development began in an era when refrigerators were still made of wood.
Launched the predecessor "Papirogin." Born as an ear drop medicine for people suffering from ear pain and itching.
Renamed and inherited as "Papinarin." The only Class 2 OTC Drug approved in Japan for the treatment of external auditory canal inflammation (otitis externa).
Loved by many for over 70 years with an unchanged formula since its launch. Manufactured and sold consistently by Harasawa Pharmaceutical Industry, headquartered in Minato-ku, Tokyo.
- Do not: Use continuously for a long time (even if effective, continuous use should be within one month).
- Do not: Use only for ear drops; do not use in eyes or nose.
- Please consult a doctor, pharmacist, or registered seller before use if you: are under medical treatment, have had allergic reactions to medicines, have a perforated eardrum, or have a purulent affected area.
- If symptoms such as "ear: purulent symptoms, swelling, irritation" or "skin: rash, redness, itching" appear after use, stop using immediately and consult a doctor, pharmacist, or registered seller.
- If symptoms do not improve after 5 to 6 days of use, discontinue use and consult a doctor, pharmacist, or registered seller.
- Store tightly closed in a cool, dry place away from direct sunlight.
- Keep out of reach of children.
- Do not transfer to another container (this may cause misuse or change the quality).
- Do not use the product past its expiration date.










































































