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For joint swelling and pain, edema, and other discomforts related to fluid circulation and cold sensitivity
Who it’s for / When to use
Product overview
Mizunine is a tablet form of the Kampo formula “Eppikajutsuto,” made from 7 crude drugs. It is a medicine used for symptoms such as edema and joint swelling or pain in people of moderate or greater physical strength who have cold sensitivity, edema, thirst, sweating, and sometimes reduced urine output. It is also a formula considered within the labeled indications when swelling that feels like fluid collecting around the knee, and the associated pain or difficulty moving, are a concern.
Product features
Kampo formula “Eppikajutsuto”
FormulaContains Eppikajutsuto extract composed of Ephedra, Gypsum, Atractylodes lancea rhizome, Processed aconite powder, Ginger, Glycyrrhiza, and Jujube. A traditional formula configuration for patterns involving cold sensitivity and edema.
For symptoms such as joint swelling and edema
Indication areaIndications include edema, joint swelling or pain, muscle pain, and other symptoms that often appear in connection with fluid stagnation or inflammation. When a swollen feeling as if fluid has collected in the knee is a concern, it is used within this range of indications.
Easy-to-take tablet form
Dosage formThe crude drug extract is finished as tablets to be taken with water or hot water. A dosage form designed with everyday continued use in mind.
Active ingredients & excipients
| Ingredient | Amount | Category |
|---|---|---|
| Eppikajutsuto extract | 2.6 g (per daily dose) | Active ingredient |
| (Constituent crude drugs) Ephedra, Gypsum, Atractylodes lancea rhizome, Processed aconite powder, Ginger, Glycyrrhiza, Jujube | — | Crude drug |
| Anhydrous silicic acid, Aluminum silicate, CMC-Ca, Lactose, Magnesium stearate | — | Excipient |
Indications
Dosage and administration
| Age | Dose per serving | Times per day |
|---|---|---|
| Adults (15 years and older) | 4 tablets per dose | 3 times daily, before meals or between meals |
| Under 15 years | Do not take | — |
❓ Frequently asked questions
QCan people under 15 years of age take this?
ADo not give to anyone under 15 years of age.
QIs there anything to keep in mind about dosage and administration?
AFollow the prescribed dosage and administration.
QIn what cases should I consult someone before taking this?
AThis product is a Kampo formulation containing Ephedra (a crude drug that includes ephedrine alkaloids) and processed aconite powder. It may not be suitable depending on concomitant medicines or constitution, so read the package insert carefully and consult a physician, pharmacist, or registered seller before use. Pregnant women or those who may be pregnant, those who are breastfeeding, and those with chronic conditions, under medical care, or taking other medicines should consult before use.
QWhat if rash, itching, or stomach discomfort appears after taking this?
AIf symptoms such as rash/redness, itching, or stomach discomfort appear after taking this product, stop use and consult a physician, pharmacist, or registered seller.
QWhat should I do if my symptoms do not improve?
AIf symptoms do not improve, do not continue use indefinitely; consult a professional.
QCan I use this if it does not match the “sho” (pattern) in the indications?
ADo not use if it does not match the “sho” (conditions such as physical strength, cold sensitivity, and edema) corresponding to the indications.
QAre there any storage precautions?
AStore in a cool place with low humidity, away from direct sunlight. Keep out of reach of children. Do not transfer to another container. Do not use products past their expiration date.
- Do not give to anyone under 15 years of age.
- Follow the prescribed dosage and administration.
- This product is a Kampo formulation containing Ephedra (a crude drug that includes ephedrine alkaloids) and processed aconite powder. It may not be suitable depending on concomitant medicines or constitution, so read the package insert carefully and consult a physician, pharmacist, or registered seller before use.
- Pregnant women or those who may be pregnant, those who are breastfeeding, and those with chronic conditions, under medical care, or taking other medicines should consult before use.
- Do not use if it does not match the “sho” (conditions such as physical strength, cold sensitivity, and edema) corresponding to the indications.
- If symptoms such as rash/redness, itching, or stomach discomfort appear after taking this product, stop use and consult a physician, pharmacist, or registered seller.
- If symptoms do not improve, do not continue use indefinitely; consult a professional.
- Store in a cool place with low humidity, away from direct sunlight.
- Keep out of reach of children.
- Do not transfer to another container.
- Do not use products past their expiration date.

















































































