Skip to content
  • ☰ Category
  • New product
  • Set product
  • Brand List
  • Blog
  • FAQ
  • Holiday Notice
MamiGo

Your cart is empty

Continue shopping
0Cart(¥0 JPY)
  • ☰ Category
    • 参天製薬 サンテ ヒアレインS 5ml x 2本 OTC Medicines and Quasi-drugs
    • Health Foods
    • ORIHIRO Purunto Konjac Jelly Pouch Apple + Grape 12 pieces Food
    • Sweets
    • デザインの異なる缶コーヒー4本 Beverages
    • 日用品 Daily necessities
    • 美容 Beauty
    • 비염
      Rhinitis
    • 위장약
      Gastrointestinal Medicine
    • 정장 / 변비약
      Intestinal Regulators & Laxatives
    • 피부외용약
      Topical skin medicine
    • 진통소염제
      Pain Relief and Anti-inflammatory Medicine
    • 目薬
      Eye Drops
    • 영양보급
      Nutritional Supplementation
    • 특수의약품
      Special OTC Medicines
    • 生活習慣病
      Lifestyle-related diseases
    • 医療用品
      Medical Supplies
    • 감기약
      Cold Medicine
    • エスエス製薬 エスエス ブロン錠 60錠
      Cough and Throat Medicine
    • 해열 진통제
      Antipyretic Analgesics
    • 건강관리식품
      Health Care Foods
    • 美容・ダイエットケア食品
      Beauty and Diet Care Foods
    • バランス栄養食品
      Balanced Nutritional Food
    • 特定保健用食品
      Specified Health Food Products
    • 栄養機能食品
      Nutritional Functional Foods
    • Functional Food with Health Claims
    • 조미료
      seasoning
    • 香辛料
      Spices
    • カレー・シチュー
      Curry / Stew
    • 간단 요리
      Easy Cooking
    • スープ
      Soup
    • 면류
      Noodles
    • 곡물류
      Grains
    • 분말류
      Powdered Products
    • 乾物類
      Dried Foods
    • 잼 / 스프레드
      Jam / Spread
    • 디저트
      Dessert
    • チョコレート
      Chocolate
    • ビスケット
      Biscuit
    • クッキー
      Cookie
    • スナック菓子
      Snack Confectionery
    • ケーキ
      Cake
    • パイ
      Pie
    • 和菓子
      Japanese Sweets
    • 米菓子
      Rice Snacks
    • 豆菓子
      Bean Snacks
    • こども菓子
      Children's Sweets
    • 飴
      Candy
    • グミ
      Gummy
    • 珍味
      Delicacies
    • 水
      Water
    • ソフトドリンク
      Soft drink
    • ノンアルコール
      Non-alcoholic
    • コーヒー
      Coffee
    • ラテ
      Latte
    • ココア
      Cocoa
    • 日本茶
      Japanese Tea
    • 紅茶
      black tea
    • 中国茶
      Chinese Tea
    • 健康茶
      Health Tea
    • 青汁
      Green Juice
    • その他の飲料
      Other Beverages
    • 家庭用医療用品
      Home Medical Supplies
    • 衛生用品
      Hygiene Products
    • 生活環境用品
      Living Environment Supplies
    • 洗剤
      Detergent
    • Kitchen Supplies
    • Cleaning Supplies
    • ベビー・マタニティ用品
      Baby & Maternity Products
    • 化粧品
      Cosmetics
    • バス用品
      Bath Products
    • ボディケア用品
      Body Care Products
    • ヘアケア用品
      Hair Care Products
    • オーラルケア用品
      Oral care products
    • エチケット用品
      Etiquette Supplies
  • New productNew
  • Set product
  • Brand List
  • Blog
  • FAQ
  • Holiday Notice
Home Smile 40 Premium THE ONE Cool
LION スマイル40 プレミアム THE ONE クール 15ml
LION スマイル40 プレミアム THE ONE シリーズ
LION スマイル40 プレミアム THE ONE クール 15ml
LION スマイル40 プレミアム THE ONE シリーズ
LionSKU: 4903301363286

Smile 40 Premium THE ONE Cool

¥1,618 JPY /
Tax included. Shipping calculated at checkout.
Class 2 OTC drugs

Product name : Smile 40 Premium THE ONE Cool
selection 15ml
LION スマイル40 プレミアム THE ONE クール 15ml
Smile 40 Premium THE ONE Cool
¥1,618 JPY /
selection 15ml
 
 
Class 2 OTC DrugGeneral-purpose eye dropsEye drops

Smile 40 Premium THE ONE Cool

Eye drops for eye fatigue, blurred vision, redness, and itching

Cooling sensation level: 4

For whom / when

✦
When bothered by eye fatigue or blurred vision Eye drops for eye fatigue. They can also be used for blurred vision (such as when there is a lot of eye discharge).
✦
When bothered by eye redness or itching Can be used for conjunctival redness. It is also indicated for itchy eyes.

Product overview

Eye drops for eye fatigue, blurred vision (such as when there is a lot of eye discharge), conjunctival redness, itchy eyes, and other symptoms. Vitamin A acts directly on the cornea and supports visual function. Sodium chondroitin sulfate keeps eyes moist and protects the cornea.

No preservatives are added. Do not use while wearing soft contact lenses.

Product features

01

Smile's proprietary technology

Smile uses its proprietary technology to provide a preservative effect.

02

Expiration date and storage

The product can be used and stored in the same way as eye drops containing preservatives, including with regard to expiration date and storage.

Conditions and precautions for use

*1 Caused by mild rubbing

*2 Standards refer to the scope of medicines established by the Ministry of Health, Labour and Welfare to streamline the approval process.

Read more about its features

One common cause of eye fatigue, blurred vision, redness, and itching

Contains vitamin A to repair corneal damage*1

Treat all these symptoms with just one bottle!

Contains 12 active ingredients, the most in Japan (within the standards*2)

Cause-focused approach × symptom-focused approach

*1 Caused by mild rubbing

*2 Standards refer to the scope of medicines established by the Ministry of Health, Labour and Welfare to streamline the approval process.

No preservatives added

Smile uses its proprietary technology to provide a preservative effect. No preservatives (such as benzalkonium chloride) are added. The product can be used and stored in the same way as eye drops containing preservatives, including with regard to expiration date and storage.

Cooling sensation level: 4

Active ingredients (per 100 mL)

Active ingredient Content Function
Retinol palmitate (vitamin A) 50,000 units A vitamin that acts directly on the cornea and supports visual function.
d-α-Tocopherol acetate (natural vitamin E) 0.045g A vitamin that promotes blood circulation and supplies nutrients to the eyes.
Pyridoxine hydrochloride (vitamin B6) 0.01g A vitamin that helps promote metabolism.
Sodium chondroitin sulfate 0.1g Keeps eyes moist and protects the cornea.
Taurine 1g Amino acids that help promote metabolism.
L-potassium aspartate 0.8g Amino acids that help the eyes take in oxygen.
Neostigmine methyl sulfate 0.005g Improves the eye's focusing function.
Chlorpheniramine maleate 0.03g Relieves discomfort such as itchy eyes.
Tetrahydrozoline hydrochloride 0.02g Relieves eye redness.
Epsilon-aminocaproic acid 1g Relieves eye inflammation.
Berberine chloride hydrate 0.015g An herbal medicine-derived ingredient with antibacterial and anti-inflammatory effects.
Dipotassium glycyrrhizinate 0.25g An herbal medicine-derived ingredient with anti-inflammatory effects.

Contains the following additives: boric acid, trometamol, sodium edetate, BHT, propylene glycol, povidone, hypromellose, polyoxyethylene polyoxypropylene glycol, l-menthol, d-borneol, and pH adjuster.

Indications

Eye strain Blurred vision (such as when there is a lot of eye discharge) Conjunctival redness Itchy eyes Blepharitis (sore eyelids) Prevention of eye disease (after swimming, or when dust or sweat gets in the eyes) Eye inflammation caused by ultraviolet rays or other light (such as snow blindness) Discomfort while wearing hard Contact lenses

Directions and Dosage

Instill 1–3 drops in the eye 3–6 times a day. (1)Excessive use may cause unusual sensitivity to light or, conversely, redness. (2)When giving this product to children, ensure it is used under the guidance and supervision of a parent or guardian. (3)Do not let the tip of the container touch the eye, eyelid, or eyelashes (this may cause contamination or foreign matter, such as eye discharge or dust, to get in). Do not use if the Liquid is cloudy. (4)Do not use while wearing soft Contact lenses. (5)For use as eye drops only.
⚠️ Precautions for Use

Consultation

  • 1. The following people should consult a doctor, pharmacist, or registered pharmacist before use.
  • (1)People receiving medical treatment.
  • (2)People who have had allergic symptoms caused by medicines or other substances.
  • (3)People with the following symptom: severe eye pain.
  • (4)People diagnosed with glaucoma.
  • 2. If any of the following symptoms occur after use, they may be side effects. Stop use immediately and consult a doctor, pharmacist, or registered pharmacist, bringing this document with you.
    Affected area Symptoms
    Skin Rash, redness, itching
    Eyes Redness, itching, swelling, stinging pain
  • 3. Stop use in the following cases and consult a doctor, pharmacist, or registered pharmacist, bringing this document with you.
  • (1)If blurred vision does not improve.
  • (2)If symptoms do not improve after 5–6 days of use.
  • Contains ingredients that increase viscosity. Vision may be temporarily blurred after use, so take care.
📦 Storage Precautions
  • (1)Store tightly closed in a cool place away from direct sunlight.
  • To maintain quality, do not leave the product in hot places (40°C or above), such as inside a car or near a heater.
  • (2)Keep out of reach of children.
  • (3)Do not transfer the product to another container (this may cause misuse or affect its quality).
  • (4)Do not share with others.
  • (5)Do not use the product after its expiration date (printed on the bottom of the outer box). Even before the expiration date, use it as soon as possible after opening.
  • (6)If you instill the drops while holding the container sideways, or depending on storage conditions, crystals of the ingredients may form on the tip or cap.
  • If this happens, gently wipe it off with clean gauze before use.
  • (7)The Liquid is yellow because it contains ingredients derived from crude drugs. It may stain clothing and other items, so take care to avoid spills.
  • (8)An oxygen absorber is included to maintain quality.
  • After opening the clear film, discard the oxygen absorber.
  • ◇To protect the natural environment, no carry bag is included.

● Features
One of the common causes of eye fatigue, blurriness, redness, and itching
Contains vitamin A that repairs corneal damage※1
Treats all these symptoms with just one bottle!
Contains the largest number of 12 types of active ingredients domestically (within standards※2)
Cause approach × symptom approach
※1 Mild abrasion
※2 Standards refer to the range of pharmaceuticals established by the Ministry of Health, Labour and Welfare to streamline approval procedures
■Preservative-free
Our unique Smile technology provides preservative effects. No preservatives (such as benzalkonium chloride) are included. The expiration date and storage method can be used the same as eye drops containing preservatives.

【Class 2 OTC Drug】

●Efficacy/Effects
Eye fatigue, blurred vision (such as when there is a lot of eye discharge), conjunctival redness, eye itching, blepharitis (eyelid inflammation), prevention of eye diseases (such as after swimming, when dust or sweat gets into the eyes), eye inflammation caused by ultraviolet and other rays (such as snow blindness), discomfort when wearing hard contact lenses

<Precautions related to Efficacy/Effects>


●Dosage and Administration
Instill 1 to 3 drops, 3 to 6 times a day.

<Precautions related to Dosage and Administration>
(1) Excessive use may cause abnormal glare or paradoxically cause redness.
(2) When used for children, use under the guidance and supervision of a guardian.
(3) Do not let the tip of the container touch the eyes, eyelids, or eyelashes (to prevent contamination or foreign matter such as eye discharge or dust). Do not use if the solution is cloudy.
(4) Do not use while wearing soft contact lenses.
(5) For ophthalmic use only.

●Ingredients/Quantity
Per 100mL
Retinol palmitate 50,000 units
d-α-Tocopherol acetate 0.045g
Pyridoxine hydrochloride 0.01g
Sodium chondroitin sulfate ester 0.1g
Aminoethylsulfonic acid (taurine) 1g
L-aspartic acid potassium salt 0.8g
Neostigmine methyl sulfate 0.005g
Chlorpheniramine maleate 0.03g
Tetrahydrozoline hydrochloride 0.02g
Epsilon-aminocaproic acid 1g
Berberine chloride hydrate 0.015g
Dipotassium glycyrrhizinate 0.25g

〔Additives〕
Boric acid, trometamol, edetate sodium, dibutylhydroxytoluene (BHT), propylene glycol, povidone, hypromellose (hydroxypropyl methylcellulose), polyoxyethylene polyoxypropylene glycol, l-menthol, d-borneol, pH adjuster

<Precautions related to Ingredients/Quantity>


●Dosage Form
Eye drops (external use [ophthalmic and otorhinolaryngologic solution] - liquid)

●Precautions for Use
■Consult
1. Consult a doctor, pharmacist, or registered seller before use if you:
(1) Are receiving medical treatment.
(2) Have had allergic reactions to medicines.
(3) Have the following symptoms: severe eye pain
(4) Have been diagnosed with glaucoma
2. If the following symptoms appear after use, they may be side effects. Stop use immediately and consult a doctor, pharmacist, or registered seller with this document.
[Affected area: Symptoms]
Skin: rash, redness, itching
Eyes: redness, itching, swelling, stinging pain
3. Stop use and consult a doctor, pharmacist, or registered seller with this document if:
(1) Blurred vision does not improve.
(2) Symptoms do not improve after 5 to 6 days of use.
■Other precautions
Contains high-viscosity ingredients. Temporary blurriness may occur after use, so please be careful.

●Precautions for Storage and Handling
(1) Store tightly closed in a cool place away from direct sunlight.
To maintain quality, do not leave in high-temperature places (above 40°C) such as inside a car or near heating equipment.
(2) Keep out of reach of children.
(3) Do not transfer to other containers (may cause misuse or quality changes).
(4) Do not share with others.
(5) Do not use products past the expiration date (printed on the bottom of the outer box). Even within the expiration date, use as soon as possible after opening.
(6) When instilling with the container horizontal or depending on storage conditions, crystals of ingredients may adhere to the tip or cap of the container.
In such cases, gently wipe off with clean gauze before use.
(7) The liquid is yellow due to herbal ingredients. Be careful not to stain clothing or other items.
(8) Contains an oxygen absorber to maintain quality.
Discard the oxygen absorber after opening the transparent film.
◇In consideration of the natural environment, no carrying bag is included.


My Account
Order Tracking
MamiGo
Shopping
  • Category List
  • Brand List
  • New product
  • Set product
Terms and Policies
  • Terms of Use
  • Notation based on the Act on Specified Commercial Transactions
  • Personal Information Handling Policy
  • Shop Information
Receive event information

We will notify you of the latest news, gifts, discount events, and more before anyone else.

American Express
Apple Pay
Google Pay
JCB
Mastercard
Shop Pay
Visa

© 2026 MamiGo, All rights reserved.